Researchers have managed to successfully culture stem cells from children with
a specific neurological disease in the lab
«We need region - specific and function - specific neuronal types for
specific neurological diseases.»
BIIB054 was originally developed by biotech company Neurimmune, using a platform they call Reverse Translational Medicine (RTM ®), which derives therapeutic antibody candidates from libraries of de-identified B - cells isolated from ostensibly healthy older adults (those free of
specific neurological diseases of aging).
Not exact matches
Using the same methodology we employed for Parkinson's, our plan is to study other
neurological disorders to determine whether there are
disease -
specific factors which explain any observed differences in the type of biomedical research most likely to receive a high Altmetric Attention Score.»
Copy number variants in NRXN1 have been implicated in other
neurological disorders including epilepsy and autism, but this is the first time that scientists have linked copy number variants in CNTN6 to a
specific disease.
«This new detailed view will be invaluable as we try to develop drugs that might work on
specific subunits and therefore help fight or cure some of these
neurological diseases and conditions,» Gouaux said.
A new genetic discovery in the field of Huntington's
disease (HD) could mean a more effective way in determining severity of this
neurological disease when using
specific treatments.
«To the extent that psychiatric or
neurological disease is localized to a
specific part of the brain, we should now be considering the potentially specialized type of astrocytes regulating nerve connections in that region and their contributions to
disease,» he said.
His research is based on the concept that normal brain aging and the pathogeneses of sporadic
neurological diseases are not a consequence of a few single or «
disease -
specific «factors alone, rather they are driven by holistic events that include one's individual genetic and epigenetic condition, progression of aging, and lifestyle.
He has developed novel cellular models of
neurological diseases (schizophrenia, MS, autism, Alzheimer's, Parkinson's) using human induced pluripotent stem cells (iPSCs) derived from donor patients and differentiated to
specific neuronal cell types.
Rapidly evolving approaches to the comprehensive profiling of patients» risk factors, such as whole - genome sequencing, will play an increasingly important role in overcoming
neurological disease, in much the same way as these approaches are already used to match up certain cancer patients with
specific drugs they stand to benefit from the most.
A recent study14 in Frontiers in Molecular Neuroscience notes that iron - restricted diets «affect brain ferritin levels, dopamine metabolism and cellular prion proteins in a region -
specific manner» — effects that highlight the importance of adequate iron for general brain health and for the prevention of
neurological diseases.
I also study the immunological and
neurological mechanisms involved in nutrition, herbal medicine, acupuncture, and mind - body therapies, with
specific interest in the gut - brain axis in Parkinson's
disease.
Neurology Nurse Clinical Management Services, Baltimore, MD 2008 — Present • Assess assigned patients to determine their
specific neurological problems and
diseases.
Of studies involving patients with a pre-existing diagnosis, 44 % were
specific to cardiovascular
disease (CVD), 36 % to cancer, 9 % to renal
disease, and the remaining 11 % had a variety of conditions including
neurological disease.