Sentences with phrase «specific neutralizing»

Assays for virus - specific neutralizing antibodies were performed on serial 2-fold diluted samples of each serum using 2 % FBS - DMEM as the diluent in 96 - well tissue culture plates (Falcon 3072); the final volume of the serially diluted samples in each well was 60 µl after addition of 120 TCID50 of SARS - CoV in 60 µl into each well.

A purified inactivated virus vaccine derived from a Puerto Rican strain was shown to induce ZIKV - specific neutralizing Abs and protect from virus challenge in mice and NHP models (115), and DNA vaccines encoding the prM / E genes of ZIKV elicited strong binding and neutralizing Abs in rhesus monkeys (116, 117).

A clinically ill family member, despite having no contact with the CNPRC, also tested positive, and screening of a set of 81 random adult blood donors from the Western United States detected TMAdV - specific neutralizing antibodies in 2 individuals (2/81, or 2.5 %).

The study, published in Scientific Reports, demonstrated that animals injected with synthetic DNA engineered to encode a specific neutralizing antibody against the dengue virus were capable of producing the exact antibodies necessary to protect against disease, without the need for standard antigen - based vaccination.

The research team plucked seven MERS - specific neutralizing antibodies from the library after using samples of the virus to screen for them.

Not exact matches

Those of us who are not personally favored with such specific revelations must stand outside of them altogether and, for the present at least, decide that, since they corroborate incompatible theological doctrines, they neutralize one another and leave no fixed result.

(91) Yes — However, the use of cleaners not listed in tables 7.3 or 7.4 (PSL) is permitted under specific conditions laid out in 8.2.3 (32.310): 1) the efficacy of the alternative cleaning substance is documented; 2) the cleaning materials used are effectively removed from the product contact surfaces, by an acceptable removal event (see 3.59 «removal event» definition) and that process documented; 4) the disposal of the effluent has been neutralized to minimize the environmental impact.

Broadly neutralizing antibodies specific to HIV have a few quirky features, one of which is the presence of a long stretch of amino acids that sticks out from the antibody surface.

A neutralizing antibody is one that not only recognizes a specific virus but also prevents it from infecting host cells, so eventually the infection is «cleared» from the individual.

In the so - called humoral response, B - cells begin to secrete specific antibody proteins, which latch onto and neutralize pathogens in tissue or blood.

Monoclonal antibodies, which bind to and neutralize specific pathogens and toxins, have emerged as one of the most promising treatments for Ebola patients.

TAL effectors are produced in nature by certain bacteria that infect plants and are able to bind to specific sequences in the plant DNA, thereby neutralizing the plant's defense mechanisms.

Experiments in tissue culture using neutralizing antibodies and CD155 receptor — specific antibodies and neurovirulence tests inCD155 transgenic mice confirmed that the synthetic virus had biochemical and pathogenic characteristics of poliovirus.

Researchers at the Childhood Obesity Research Center at USC are looking at how maternal food intake affects fructose levels in breast milk as well as how specific elements in breast milk can alter a baby's developing gut bacteria, which neutralizes toxic byproducts of digestion.

Then the pIgR system carries the IgA antibody inside the cyst, where it neutralizes a specific receptor.

Johannes Scheid, a student in Nussenzweig's lab, isolated it several years ago from an HIV - infected patient whose immune system had an exceptional ability to neutralize HIV in the blood by preventing the virus from infecting and destroying a specific type of immune cells, called CD4 cells, in patients.

The decreased levels of neutralizing Abs to TMAdV in the researcher (1 ∶ 32) and a family member (1 ∶ 8) relative to those in infected titi monkeys (up to > 1 ∶ 512) are consistent with a recent study showing much higher levels of neutralizing antibodies in chimpanzees than in humans with adenovirus infections, possibly due to more robust adenovirus - specific T - cell responses in humans than in monkeys [45].

Based on these observations, we postulate that the plasmablasts producing these broadly neutralizing antibodies were predominantly derived from activated memory B cells specific for epitopes conserved in several influenza strains.

It is possible, for example, to examine the effects of a recombinant bacterial toxin on infection, but it is more difficult to examine the role of specific virulence factors in neutralizing specific elements of the immune system, such as phagocytes.

In this context, the Lingwood laboratory studies B cell antibody responses to both HIV and influenza with the goal of 1) understanding how antigenic sites of vulnerability are initially perceived by specific germline B cell receptor (BCR) sequences and 2) how that recognition process can direct antibody affinity maturation toward production of broadly neutralizing anti-viral responses.

The broadly neutralizing antibody 10 - 1074 targets a specific structure on the surface of the HIV virus.

Johannes Scheid, awarded for hos essay in the category Translational Medicine: «HIV Specific B cell Response in Patients with Broadly Neutralizing Serum Activity»

These proteins bind to specific antigen proteins on the surface of foreign bodies such as bacteria and viruses in order to neutralize or disarm them.

Following positive initial results from Phase I safety trials evaluating direct administration of VRC01, an HIV - specific antibody that is able to neutralize a broad variety of HIV strains, the National Institute of Allergy and Infectious Diseases (NIAID) is preparing for a series of further studies to see if this broadly neutralizing antibody is effective in preventing transmission of HIV from mothers to their infants, as well as among high - risk adults.

This assay is not specific for POWV, and neutralizing antibody was confirmed in only two of the birds in a single study [43].

Curcumin, the main active ingredient in turmeric has proven anti-inflammatory and antoxidant effects — it can target multiple steps in the inflammatory pathway at the molecular level and it can neutralize free radicals due to its specific chemical structure.

And while that will certainly help, you can also simply neutralize the inflammation in your body with specific fruits and vegetables.

Glutathione is reduced by these toxic free radicals, neutralizing them, and then this glutathione is normally recycled and becomes oxidized by a specific enzyme, so that it can then fulfill it's purpose once again.

I will stop here with specific comparisons that I did with the Nexus and say that I certainly hope the next version of the Fire will neutralize these hardware advantages.

CAV - 2 specific serum neutralizing antibody responses were observed in all vaccinated dogs, indicating effective immunization.

Monoclonal antibodies (mAbs) are developed in a laboratory from a single cell line and, when administered to patients, target and neutralize specific antigens.

In cross-examining the accused (if he or she testifies), the Crown can cross-examine not only on general reputation, but on specific acts of bad character or misconduct that are similar in nature to the offences charged, in order to neutralize the evidence of good character.204 The trial judge retains the discretion to disallow such cross-examination where it would result in undue prejudice.205 If the accused made a statement to police that has been ruled voluntary, and there is an admission therein which is contrary to the evidence led by the accused in relation to his or her good character, the Crown should consider cross-examining the accused on that prior inconsistent statement.

The easiest change to make is to go through your existing resume word - by - word and «neutralize» any language that is industry specific.