The goal of this project is to identify
the specific nucleotide sequences and / or single nucleotide polymorphisms that are correlated with expression of virulence and disease via comparative genomic analysis between B. pseudomallei strains as well as between various bacteriophages harbored within B. pseudomallei.
Both the modification and the restriction enzymes become activated on a short
specific nucleotide sequence, the recognition sequence, which is the substrate for methylation.
Not exact matches
The
specific sequence of
nucleotides determines the various kinds of life that appear in evolution.
Microspheres are then able to use proteinoids as templates to make polynucleotides, which are themselves nonrandom because
specific three -
nucleotide sequences bind preferentially to
specific amino acids.
Every tissue in an organism contains a variety of messenger RNA molecules, single - stranded
nucleotide sequences bearing instructions for the making of
specific proteins.
DNA is made of four substances — the
nucleotide bases adenine, guanine, thymine, and cytosine — that will combine only in
specific configurations and
sequences.
Extensive research has already examined the function of microRNAs, a category of small evolutionarily conserved noncoding RNAs about 22 to 24
nucleotides in length that target protein - coding genes in a
sequence -
specific manner.
During development, chromosomes are subject to chemical changes that don't affect the
nucleotide sequence but can turn genes on or off; the best known example is methylation, in which a methyl group is attached to
specific DNA regions.
To make the match more
specific, Cas9 requires an additional
sequence flanking the targeted 20
nucleotides: N - G - G, in which «N» can be any
nucleotide.
In the presence of a donor DNA molecule with homology to the target region, the CRISPR system can also be used to introduce
specific nucleotide modifications into a
sequence of interest.
In this study, we have developed a new sensitive and
specific one step rRT - PCR for detection of ZIKV in serum and cell culture supernatants using a Taqman probe containing locked
nucleotides, in the NS5 region of ZIKV genome using
sequences of ZIKV strains circulating in Africa and Asia.
Silence's
specific siRNA molecules exhibit unique structural features which, irrespective of their individual
nucleotide sequence, bar third parties from commercialising this type of molecule.
A single DNA
sequence is formed from a chain of four
nucleotide bases and if some individuals in a population do not carry the same
nucleotide at a
specific position in the
sequence, the variation is classified as an SNP.
Studying a
specific type of genetic variation in the DNA
sequences of wolves and domestic dogs - called Single
Nucleotide Polymorphisms (SNPs)- the scientists identified the transfer of dog gene variants into wolf genomes.
In DNA, each protein is encoded by a gene (a
specific sequence of DNA
nucleotides that specify how a single protein is to be made).
Therefore, each tRNA has a
specific three -
nucleotide sequence called an anti-codon that matches up with the appropriate mRNA codon, like a lock and key.