Both methods have advantages and disadvantages, but the optimum method would be to be able to quantify the connection between the smell that the human nose experiences and the actual, measured amount of
specific odorants in the air.
This achievement will enable quick and easy exhaustive analysis of ORs responding to
specific odorants, which previously required a great deal of time and effort.
Using the Single - Cell Automatic Analysis and Isolation System developed in 2013, this group isolated single OSNs responding to
specific odorants in a time - lapse single - cell - array cytometric manner and identified the OR gene through single cell polymerase chain reaction (PCR).
«New method for exhaustively isolating olfactory receptors responding to
specific odorants: Step toward the elucidation of a mechanism for recognizing odorants in mammals.»
Not exact matches
In addition, each foodstuff has its own odor code comprised of a core group of between just 3 and 40 of the 230 key
odorants — in
specific concentrations.
Each odor - detecting neuron (referred to as olfactory sensory neuron from here on), chooses a single
odorant receptor gene from a fairly large number of options that are split into class I (fish - like) and class II (terrestrial -
specific)
odorant receptors.
A.
Odorant -
specific pleasantness ratings for native Ethiopians (blue), native Israelis (brown), and eNose (pink).
Important advances have included the discovery of the first evidence that the odour response is governed by neurons, of the intracellular signalling pathways between
odorant receptors and sensory neurons, and of
specific neurons, receptors and neurotransmitters involved in behaviour adaption following experience.
However, we show that olfactory stimulation with particular
odorants results in modulation of dozens of OSN subtypes in a subtle but reproducible,
specific and time - dependent manner.