«Glandular» supplements are derived from
specific organs and tissues in the body, such as adrenal or thyroid glands, and are particularly helpful at providing the nutritional constituents that these organ systems need to function properly.
Freeze - dried concentrates of
specific organs and tissues are used to treat degenerative conditions.
Different types of tumors show a preference for
specific organs and tissues; circulating breast cancer cells, for example, are likely to take root in bones, lungs, and the brain.
Understanding exactly how stem cells form into
specific organs and tissues is the holy grail of regenerative medicine.
Not exact matches
The TEER measurement is used to quantify the flow of ions between electrodes
and across the
tissue -
tissue interface made of an
organ - specific epithelium and endothelium that is a core component of many of the Institute's human Organ C
organ -
specific epithelium
and endothelium that is a core component of many of the Institute's human
Organ C
Organ Chips.
This work provides a proof of principle for a new approach in the study
and treatment of cancer: the aberrant expression in a
tissue or
organ of genes
specific to other
tissues could become a new tool for establishing a prognosis
and personalizing therapeutic care.
«Once we had discovered 120 new variants, we started testing them
and, lo
and behold, some were significantly better in terms of gene transfer efficiency to
specific tissues and organs,» Wilson says.
Key proteins, produced
and regulated by these important genes, activated a cascade of diverse,
tissue -
specific signals that led to regenerative
organ growth.
Recent experiments, for instance, suggest that when an
organ lacks LGR -5-positive cells, differentiated cells may be able to «dedifferentiate»
and repair
tissues — a radical change from the one - way street toward
specific identities that stem cells were thought to travel.
These «nanoswimmers» cross the blood — brain barrier highly efficiently,
and could lead to the development of drug delivery systems that navigate through
tissues and organs to target
specific sites precisely.
A series of headline - grabbing results in the late 1990s
and early this decade suggested that
specific adult stem cells such as those from the blood seemed able to exceed expectations
and transform themselves into other
organs and tissues.
Contrast agents, injected into the patient during an MRI procedure
and designed to be quickly cleared from the body by the kidneys afterwards, are needed to make fine details of
organ structures, blood vessels,
and other
specific tissues clearly visible in the images.
From these three cell populations different functional
tissue cells arise, such as skin cells, muscle cells,
and specific organ cells.
«Linking the navigation capability with these new results would allow therapeutics to be delivered directly to a
specific site of the brain, potentially improving significantly the efficacy of the treatment while avoiding systemic circulation of toxic agents that affect healthy
tissues and organs,» Carret added.
The Salk researchers stopped the cells from differentiating further, but each germ layer was theoretically capable of giving rise to
specific tissues and organs.
The atlas now also includes RNA transcript data for 27 of these
organ -
specific tissues using next generation sequencing, providing a
tissue distribution map of both protein
and gene expression.
«This data allows classification of all human protein - coding genes into those coding for house - hold functions (present in all cells)
and those that are
tissue -
specific genes with highly specialized expression in particular
organs and tissues, such as kidney, liver, brain, heart, pancreas.
«We are truly excited about the RNA transcript data
and the map of gene expression that we now have for 27 different
organ -
specific tissues», says Professor Mathias Uhlén, Program Director of the Human Protein Atlas.
We can obtain iPS cells from an individual's skin or blood
and program them into different
tissue types to create patient -
specific Organ - Chips.
Following the delineation of some of the basic principles behind bud formation, the researchers then whether they could extend this strategy beyond the liver,
and create other
organ buds using
tissue specific cell types.
Moreover,
tissues,
organs and organ systems team up to perform
specific tasks such as the body's first line of defense against bacteria or viruses.
Ideally, the researchers found that the best targets were genes or proteins primarily expressed in one
specific tissue, so the drug treats the disease at its core, without interfering with other, healthy
tissues or
organs,
and thus causes fewer side - effects.
Therefore the group studies with sophisticated imaging technology in vitro
and ex vivo: i) the molecular mechanism driving the migration of HIV through the intestinal epithelial barrier; ii) the cellular targets in the mucosa, in
specific macrophages
and DCs, to identify the possible pathways to invade the
tissue and disseminate to other
organs; iii) the involvement of DCs
and their functional properties in mediating adaptive immune responses at mucosal level;
and iv) the role of antibodies with different effector functions in changing the pathways of the virus.
In other words, peptides are
tissue -
specific and have beneficial effects on the
organs which they were extracted from.
Endogenous (produced inside the body) HGH puts its actions into effect by «molecularly» joining straight to particular receptors on
specific muscle
tissues which includes muscles, connective
tissue (tendons, ligaments, bone,
and fat), as well as just about every major
organ.
Autoimmune diseases are characterized by
tissue damage
and loss of function due to an immune response that is directed against
specific organs.
They drip, if you will, into the bloodstream where they travel to the distant
tissues and organs, where they then bind to the
tissues»
and organs»
specific cell sites called receptors.
HCG can be found in every
tissue of the body, including both male
and female
specific organs.
Eventually, studies done using dye showed that enzymes, hormones, peptides
and proteins in fact are absorbed intact
and are able to target
specific tissues and organs.
The current uproar was ignited when an antiabortion activist, posing as a biomedical research company representative, captured on video — which he then edited in the most misleading way possible — discussions by Planned Parenthood physicians of the procedures they use (when recovering
specific fetal
organ tissues)
and the cost ($ 30 to $ 100 to reimburse for costs).