Sentences with phrase «specific resistance genes»

With the premise that accumulation of putative resistance - conferring SNPs, potentially in combination with specific resistance genes, precedes full resistance, we retrogressively surveyed the hotspot loci and quantified the number of SNPs and / or genes, which if accumulated would confer full resistance to an otherwise susceptible strain.

Professor Bruce Fitt, professor of plant pathology at the University of Hertfordshire, added: «This new understanding of plant defense through ETD suggests different operations of specific resistance genes which will help us to be more successful in breeding new strains of crops for resistance.

We identified some specific resistance genes that code for receptor - like proteis (RLPs) and described how they operated against the pathogens.

Not exact matches

It will also allow for easier identification of genes that contribute to the bacteria's spread from patient to patient, and more meaningful scientific experiments to understand the bug's resistance to antibiotics or identify new antimicrobial compounds that target specific genes necessary for maintaining these persistent infections.

Analysing the samples, the team — involving experts from Newcastle University, the University of Strathclyde and Aarhus University — were able to measure the relative abundance of specific β - lactam antibiotic resistant genes, which can confer resistance to a class of antibiotics that are of considerable medical importance.

«By comparing the two timelines, we saw the appearance of each specific gene in the soil samples was consistent with the evolution of similar types of resistance in medicine.

His current specific interest is the elucidation of novel mechanisms of drug resistance through the discovery / identification of novel gene function (s) and phenotypes using RNAi - mediated gene silencing or cDNA overexpression.

Hendrik is preparing the publication of the most complete woolly mammoth genome yet, and Harvard geneticist George Church's team is already working to introduce specific DNA variants — genes for hair, tusks, subcutaneous fat and cold resistance — into cultured cells from Asian elephants (right).

In 2009, researchers at Dow AgroSciences in Indianapolis, Indiana, and Sangamo BioSciences in Richmond, California, announced that they had used enzymes called zinc - finger nucleases to insert a gene for herbicide resistance at a specific site in the maize genome (V. K. Shukla et al..

Using biopsies of the patients» tumors collected before the start of treatment and at the time patients developed resistance, the researchers performed large - scale genomic analyses to search for mutations specific to the cancer cells in all of each patient's 20,000 genes.

«If we could understand better how these proteins with these additional «integrated» domains were formed during recent evolution, then there is a good chance that we could engineer genes with specific domains to provide resistance to new types of pathogen attack,» says Paul Bailey, lead author of the study who performed the phylogenetic analysis.

The Yale - led study performed whole exome sequencing ¬ — a technique for sequencing all the expressed genes in a genome ¬ — on TNBC tumors to identify mutations in specific genes or pathways that may indicate response or resistance to the standard of care, which is anthracycline / taxane (ACT) chemotherapy.

«Even though the specific molecular changes that are found in PCB - resistant tomcod and killifish are different, in both species AHR2 seems to be one of the genes — possibly the major gene — that is responsible for the resistance,» Hahn said.

Monitoring parasite populations for a specific genetic background — in this case, a fixed set of four well - defined mutations in the fd, arps10, mdr2, and crt genes — could allow researchers to assess the likelihood of new resistance - causing mutations emerging in different locations, helping to target high - risk regions even before resistant parasites take hold.

These genes typically encode immune receptors that recognize specific protein components of the fungal pathogen to trigger resistance.

Therefore, strategies for understanding mechanisms of resistance and determining how to therapeutically target specific gene fusion partners are also being explored.

For the rice plant to effectively combat blast, scientists at IRRI are combining into the same rice type different race - specific genes and genes conferring quantitative resistance.

Even if a specific defense gene enables the plant to detect and stop an infection, the pathogen can evolve a new strategy to overcome the plant's resistance.

Primers specific for the hygromycin resistance gene were used alongside control primers to sites in the Hex promoter region.

There are two general types of resistance genes found in wheat: Race - specific genes confer a high - level of resistance to specific strains of leaf rust but can be easily overcome by genetic mutation in pathogen populations, while slow rusting (APR) resistance provides partial resistance to a broad spectrum of races, but is typically effective only at the adult stage of plant growth.

The researchers also determined that amplification of a specific chromosome, and a particular gene called MAPK14 on that chromosome, may be a predictor of sensitivity to treatment, while deletions of other genes predicted resistance.

The phrase «multidrug resistance mutation 1 (MDR1)» refers to a specific mutation that can occur at a gene known as the MDR1 gene, also known as the ABCB1 gene.