As I travel throughout India and the United States to research yoga therapy, I notice that even masters who write books and articles recommending
specific sequences for particular conditions often don't use these sequences when they work with students.
Not exact matches
Says Roberts: «He quickly figured out that if Illumina was successful, it would need more than the world's supply of oligonucleotides» — the short snippets of nucleic acid that are designed to pair up with
specific genetic
sequences, and which are critical
for DNA or RNA analysis.
«We will be sending samples
for genome
sequencing to establish the
specific strain of listeria,» the company said in a statement adding that the level detected was well within the range of government standards
for the presence of listeria.
In order to save their lives, the astronauts aboard Apollo 13,
for example, had to manually shut down and restart the command module in a
specific sequence, and gain access to and activate the lunar module to supply themselves with oxygen — incredibly difficult tasks
for anyone but a trained astronaut.
Unlike genotyping, which just looks
for specific parts of DNA and pieces them together, next - generation
sequencing looks at only the protein - encoding parts of your genome, called the exome.
Most of the messages I send
for clients are not «one - off» messages, they are a structured, timed
sequence of messages leading to a
specific outcome.
There is no evidence
for a benefit to introducing complementary foods in any
specific sequence or at any
specific rate.
It consists of a pair of molecular scissors
for cutting a DNA strand, and a guide part that binds to a
specific DNA
sequence.
An international team led by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a new technique
for identifying gene enhancers —
sequences of DNA that act to amplify the expression of a
specific gene — in the genomes of humans and other mammals.
Called SIF - seq,
for site -
specific integration fluorescence - activated cell sorting followed by
sequencing, this new technique complements existing genomic tools, such as ChIP - seq (chromatin immunoprecipitation followed by
sequencing), and offers some additional benefits.
Every tissue in an organism contains a variety of messenger RNA molecules, single - stranded nucleotide
sequences bearing instructions
for the making of
specific proteins.
In order to find the best protein or peptide
sequence for a
specific function, they must simulate thousands of designs and search
for the most effective option.
Fascinated by the anatomy of horses and other animals in motion since his teens, Horváth knew that most four - legged mammals (except primates) walk using a
specific footfall
sequence — left hind, left fore, right hind, right fore —
for maximum stability.
Therefore, before publication, large data sets (including microarray data, protein or DNA
sequences, atomic coordinates or electron microscopy maps
for molecular and macromolecular structures, and climate data) must be deposited in an approved database and an accession number or a
specific access address must be included in the published paper.
It's among these
sequences that Han hopes to find useful diagnostic signatures
for specific diseases.
Sosa and I pulled on latex gloves and carefully pipetted liquids into tubes to make our guide RNA from scratch — we first synthesized DNA strands with a
specific sequence we wanted, used that as a template
for the RNA, then destroyed the DNA and isolated the guide RNA from our test tube mixture.
«You can tailor their
sequences in such a way that you can tune them
for specific functions,» de la Fuente says.
Apart from using a host of cutting - edge molecular techniques such as Next Generation
Sequencing or NGS, the researchers also had to develop
specific bioinformatic tools
for analysing large amounts of genomic data.
In the paper, the scientists show that combining the drug - resistance profile of a bacteria with its whole - genome DNA
sequence allowed them to build up a series of drug - resistance «DNA photofits»
for resistance to
specific drugs.
«
For the first time, we developed a
sequence -
specific and clinically feasible method to activate expression of the paternal Ube3a allele,» said the authors in the report.
The development shows that
for the first time, it is feasible
for researchers to identify the individual causes of lupus in patients by using DNA
sequencing, allowing doctors to target
specific treatments to individual patients.
In recent years, several
sequencing - based assays have been developed, but their clinical applicability and utility
for patients with
specific mutations still needs to be shown.
Conventional genetic screening looks
for specific mutated
sequences of DNA, but the Dutch test simply searches
for proteins which are shorter than those produced by healthy genes.
Most available tests
for the virus rely on a technology called reverse - transcriptase polymerase chain reaction (RT - PCR), which detects genetic
sequences specific to Ebola in blood, serum and other bodily fluids.
Over the longer term, the identification of the coffee tree genome
sequence opens up new possibilities
for varietal improvement, knowledge of the
specific functions of the genes (in particular those
specific to coffee trees), the possibility of transferring results to other species, and refining diagnostic tools
for the function of the plant.
Given that most transport systems are exquisitely substrate
specific, how are diverse protein
sequences recognized
for translocation?
Large scale
sequencing approach and genome wide analysis can be applied on different economic crops
for better understanding their evolutionary process and
specific traits, providing unique opportunities
for further applications.»
Thus transformation provides an in vivo assay
for the functional role of DNA
sequence organization about
specific genes.
Using next - generation
sequencing (NGS) technology, researchers were able to pinpoint
specific areas of a person's DNA to more effectively diagnose genetic forms of high - cholesterol, which markedly increase risk
for heart attack and stroke.
These findings provide evidence
for germ line transmission of an extragenic
sequence -
specific silencing factor and implicate rde - 1 and rde - 4 in the formation of the inherited agent.
It is now possible to perform whole - genome shotgun
sequencing as well as capture of
specific genomic regions
for extinct organisms.
The students went around Bangalore and into the forests of the state of Karnataka, brought soil samples and looked
for BioBrick -
specific DNA
sequences in the soil microbes.
Robert Cook - Deegan, director of the Institute
for Genome Sciences and Policy at Duke University, does credit Myriad with discovering
specific mutation
sequences and building a public database of genetic variations — both valuable contributions.
Next, the team asked four healthy adult volunteers to consume the same
sequence of four
specific diets
for about two days each: nuts and dried berries; beans, corn and rice; pasta and marinara sauce; and an egg, sausage and cheese sandwich and peas.
The researchers» next step is to use the genomic data they collected from the families — including full genome
sequences and gene expression data — to begin identifying the
specific genes that contribute to risk
for bipolar disorder.
Furthermore, besides offering valuable insight into the function of this novel RNA type, the researchers also believe that the findings will open new avenues
for novel treatments in which cell -
specific enhancer
sequences can be targeted to alter gene expression.
«The ribonucleotides are not randomly distributed, and there is some preference
for specific base
sequences and
specific base composition of the ribonucleotide itself,» said Koh.
Because Ebola diagnostics and some therapeutics like vaccines are based on the
specific viral
sequence, it is important
for researchers to have the most up - to - date virus genome
sequence possible.
The
sequence data provided evidence
for possible interspecific transfer of DWV, IAPV and BQCV, but SBV strains were species -
specific.
Some small RNAs need to match the target
sequence exactly to identify them, like a security guard looking
for a
specific person.
«Prior research in the field has primarily focused on using knowledge from tumor tissue
sequencing to identify
specific changes to look
for in circulating tumor DNA.
«DNA
sequencing procedures... allow
for identification of parentage, more distant relatives, founders to new populations, unidentified individuals, population structure, effective population size, population -
specific markers, etc.» reports Haig, adding that the result is more sophisticated information crucial to setting species recovery priorities.
It then uses CRISPR to search
for specific genetic
sequences.
This approach could now be adopted
for developing treatments
for other conditions, by generating DNA
sequences that target
specific microRNAs involved in diseases, he says.
Moreover, the ability to easily program
sequence -
specific DNA targeting and cleavage by CRISPR - Cas components, as demonstrated
for Cas9 and Cpf1, allows
for the application of CRISPR - Cas components as highly effective tools
for genetic engineering and gene regulation in a wide range of eukaryotes and prokaryotes.
«This time we
sequenced the families
for this
specific CLP1 gene mutation and all had it,» said Karaca.
The Yale - led study performed whole exome
sequencing ¬ — a technique
for sequencing all the expressed genes in a genome ¬ — on TNBC tumors to identify mutations in
specific genes or pathways that may indicate response or resistance to the standard of care, which is anthracycline / taxane (ACT) chemotherapy.
In most cases,
for a particular genetic
sequence on a
specific chromosome, the variants from each pair should be represented equally in the woman's blood.
However, Sakai's research team has discovered sites within the protein
sequence that are extremely
specific for controlling different activities of the protein.
Efforts to identify host range and cell tropism of TMAdV, as well as the
specific sequence changes responsible
for adaptation to growth in cell culture, are currently underway.