Sentences with phrase «specific sodium channel»

King believes that venom - based peptides — short chains of amino acids — are better at being selective than small molecules because the venom peptides don't target the pore; they target a specific sodium channel switch.

Not exact matches

It has been estimated that 5 % to 10 % of infants who die from SIDS have novel mutations in the cardiac sodium or potassium channel genes that result in long QT syndrome as well as in other genes that regulate channel function.44 A recent report described important new molecular and functional evidence that implicates specific SCN5A (sodium channel gene) β subunits in SIDS pathogenesis.47 The identification of polymorphisms in genes pertinent to the embryologic origin of the autonomic nervous system in SIDS cases also lends support to the hypothesis that a genetic predisposition contributes to the etiology of SIDS.

Dravet syndrome is one of the most challenging forms of childhood epilepsy, resulting from a specific genetic mutation that affects sodium channels in the brain.

«This study identifies a specific site on the channel we can target to preserve normal sodium channel and heart function even under chronic stress,» Hund said.

It acts by binding to specific receptors and allowing sodium (Na +) or calcium (Ca +) to move into brain cells through channels.