Sentences with phrase «specific subset of cells»

Not exact matches

«Unlike previous studies we isolated different immune cell types from the actual site of disease to determine whether specific subsets of immune cells (specific T cell groups) have equal sensitivity to vitamin D.»

The first key experiment involved removing a specific subset of activated T - cells from mouse models.

«Our data suggests that targeting specific immune cell subsets at defined stages of disease may represent a better approach to therapeutic immunomodulation to improve heart failure.»

Using this test, the team found that genetically - intact HIV hides in specific subsets of CD4 + T - cells.

Simultaneous T cell antigen receptor (TCR) analysis in single cells and bulk subsets revealed that CD4 - TEMRA cells show marked clonal expansion compared with TCM and TEM cells and that most of CD4 - TEMRA were dengue virus (DENV)-- specific in donors with previous DENV infection.

By cloning rat melanopsin and generating specific antibodies, we show that melanopsin is present in cell bodies, dendrites, and proximal axonal segments of a subset of rat RGCs.

Dr Peter Rugg - Gunn, group leader in the Babraham Institute's Epigenetics research programme and a senior co-author on the paper, explains: «One of the exciting aspects of this study is that we were able to capture naïve stem cells at a very early stage of their reprogramming — these early cells had switched on a subset of naïve - specific genes, but they had not yet fully matured.

Although similar numbers of total splenic gp33 - LCMV — specific T cells were observed between genotypes (Fig. 5B), the distribution of gp33 - LCMV — specific CD8 + T cell effector and memory subsets were altered, such that there was a significantly lower percentage of short - term effector T cells and reciprocal changes in memory precursor cells among gp33 - specifc CD8 + T cells in WT relative to DKO mice (Fig. 5C), with a trend in changes in absolute cell numbers, consistent with temporal data from peripheral blood (Fig. 5A).

Interaction of human mesenchymal stem cells with cells involved in alloantigen - specific immune response favors the differentiation of CD4 + T - cell subsets expressing a regulatory / suppressive phenotype.

Hedrick, whose laboratory will focus on the role of cholesterol and LDL in reprogramming specific subsets of immune cells as part of the Program Project Research grant, has assembled a high - powered, multi-institutional team, including investigators from UC San Diego and the University of Virginia.

The lab has also started to use optogenetic techniques which allows the group to modulate the activity of a specific subset of nerve cells in a reversible fashion.

To determine whether huntingtin is involved in trafficking a specific subset of proteins, we measured changes in global transcription levels in embryonic stem cells and neurons lacking huntingtin.

Genetic Analysis of HIV Genomic DNA Sequences from Phenotypic and Antigen - specific CD4 + T Cell Subsets

These include: a) Global Clusters that consist of a small, tight subset of genes that are co-expressed under the entire spectrum of experimental conditions; b) Time Series of gene expression profiles during successive days of standard ES cell differentiation; c) Specific Gene Classes based on hierarchical clustering of transcriptional factors and ESTs; d) Expression Waves of genes with characteristic expression profiles during ES cell differentiation, juxtaposed to waves of genes that behave in the exact opposite way; e) Pathway Animations that illustrate dynamic changes in the components of individual KEGG signaling and metabolic pathways viewed in time - related manner; and, f) Search Engines to display the expression pattern of any transcript, or groups of transcripts, during the course of ES cell differentiation, or to query the association of candidate genes with various FunGenES database clusters.

Feng, P.; Zhao, H.; Chai, J.; Huang, L.; Wang, J. (2012) Expression and secretion of TNF - α In mouse taste buds: a novel function of a specific subset of type II taste cells.

These cells, along with dendritic cells, recognize the incoming undigested food particles, toxic agents, and bacterial components as foreign invaders, and present them to cells of the adaptive immune system called T and B lymphocytes, leading to clonal expansion (proliferation or multiplication of specific subsets of T and B cells) and recruitment of more pro-inflammatory immune cells to the gut through a process called leukocyte homing.

To view a specific subset of data, click the drop - down arrow in the column heading of cells that contain the value or combination of values on which you want to filter, and then click the desired value in the drop - down list.