Sentences with phrase «specific therapeutic development»

Not exact matches

Targeted gene therapies, however, had to wait for (1) the identification of the genes to target, (2) the cloning and / or sequencing of the relevant genes and in some cases, the specific disease - causing variant, (3) a full understanding of the normal gene function and regulation, and (4) the development of efficient ways to deliver genes to the relevant tissues at therapeutic levels.

Combining DM1 - specific biomarkers with a large - scale screening should provide more insights into the development of new therapeutic strategies for DM1.

Scientists at the University of York have identified a therapeutic target which could lead to the development of new treatments for specific blood cancers.

The advancement of the Cas9 - based platform for screening and validation will help further the development of new therapeutic products, and Caribou's CRISPR - Cas9 technology can utilize guide RNAs specific for unique sequences and target a gene at numerous sites and therefore provide enhanced specificity.

Current pre-clinical efforts are focused on optimizing specific microbiome compositions based on functional and phylogenetic information to inform the development of therapeutic candidates.

PHENOMIN - ICS offers to generate genetically modified mouse models on a high - throughput and large scale basis, and then to provide a first phenotyping characterisation, either standardised or more specific, for a better understanding of disease mechanisms and for the development of new therapeutic treatments.

«Our findings suggest that apoE4 inhibits the development of newborn neurons by impairing specific signaling pathways and that boosting these pathways with drugs may be of therapeutic benefit,» said Dr. Huang.

The development of diagnostic and therapeutic nanodevices based on engineered recombinant proteins capable of recognizing specific tumor cell receptors is currently actively pursued.

We are therefore working to decipher the mechanism of centrosomal clustering in hematologic malignancies with a view to the development of specific inhibitors to exploit this mechanism for therapeutic ends.

In this protein, the binding domain of botulinum toxin is replaced to broaden the toxin's therapeutic potential and allow drug development to be targeted towards a specific disease.

This work will provide valuable insight into the role of microglia within canine DM disease progression and could identify key areas for the development of microglia - specific therapeutic targets that could slow or halt further disease progression.

• Determine types of therapies required for each child and develop specific therapeutic treatment plans to meet his or her individual needs • Handle assessments by interviewing and observing children and creating psychological profiles • Create new programs, move targets forward and make procedural changes in existing care / educational programs • Lead special education trainings and plan and implement staff development and patient education autism programs • Confer and communicate with staff members to gauge the effectiveness of special education programs

Dr. Anderer's areas of expertise focus on students who are both intellectually gifted and who also have specific learning disabilities, therapeutic assessment, parenting, and adolescent development.

Through didactic and experiential methods, professionals will explore the origins of shame, its development, the ways that it can interfere with the therapeutic relationship and specific management techniques.

2:15 to 4:30 pm Specific direction from trainer regarding future development of individual therapeutic skills and plans for remediation.