Sentences with phrase «specific type of the disease»

Just last October, the World Health Organization published a paper concluding that eating processed meats was linked with a higher risk of developing colorectal cancer, a specific type of the disease that begins in the colon or rectum.

But as we age, the body's production of some hormones declines, often resulting in an elevated risk of specific types of diseases or medical conditions.

Not exact matches

Therefore, it is essential that we learn how specific types of chemical modifications normally regulate RNA function in our cells, in order to understand how dysregulation of this process contributes to human disease, says Cristian Bellodi.

Firstly, three disease - specific characteristics are important: the number of viruses present in the body, the diversity of the virus types found and the duration of an untreated HIV infection.

«Only by understanding the complexities of what happens in specific cell - types found in specific areas of the brain during this disease can targeted treatments for Parkinson's disease be produced.»

«Unlike previous studies we isolated different immune cell types from the actual site of disease to determine whether specific subsets of immune cells (specific T cell groups) have equal sensitivity to vitamin D.»

The oversight of dietary supplements is loose: FDA regulations allow for several different types of efficacy claims to be made on labels, including fairly robust significant scientific agreement claims that the nutrient in question has a direct effect on a specific disease, but also so - called qualified health claims, where phrases such as some evidence suggests that are added.

This is particularly important as it indicates the method can be used in a variety of cell types to create disease models and contribute to the discovery of new disease - specific therapeutics.

«This study extends the narrative that many of the effects of disease - related genetic variation are specific to a certain context, such as a given immune cell type,» said Barbara Stranger, PhD, University of Chicago, senior study author.

The researchers studied a form of the condition called Charcot - Marie - Tooth disease type 2A, which is caused by specific genetic mutations.

Using the same methodology we employed for Parkinson's, our plan is to study other neurological disorders to determine whether there are disease - specific factors which explain any observed differences in the type of biomedical research most likely to receive a high Altmetric Attention Score.»

«Use of induced pluripotent stem cell (iPSC) technology» — which involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease — «makes it possible to model dementias that affect people later in life,» says senior study author Catherine Verfaillie of KU Leuven.

The authors state, «our findings support benefits of increased fruit and vegetable consumption for preventing long - term weight gain and provide further food - specific guidance for the prevention of obesity, a primary risk factor for type 2 diabetes, cardiovascular diseases, cancers, and many other health conditions.»

The researchers also examined the types of fruit and vegetables that may reduce the risk of specific diseases.

The study reflects an «antimicrobial stewardship» approach, guiding healthcare providers to prescribe the most appropriate antibiotic for a patient's specific type of infection, with the aim of improving individual outcomes and reducing the overall risk of antibiotic resistance — in which disease - causing microorganisms develop resistance to commonly used antibiotics.

For example, how genetic programs affect the function of specific cell types, how they vary early or later in life and how dysfunction in these programs might contribute to disease, all of which could help scientists learn more about the fundamental workings of the brain.

«To the extent that psychiatric or neurological disease is localized to a specific part of the brain, we should now be considering the potentially specialized type of astrocytes regulating nerve connections in that region and their contributions to disease,» he said.

This type of imaging uses a radioactive tracer to look for chemical signs of disease in specific tissues.

Researchers at University of California San Diego School of Medicine have discovered evidence in mice and humans that stomach (gastric) acid suppression alters specific gut bacteria in a way that promotes liver injury and progression of three types of chronic liver disease.

The combined database will allow scientists to puzzle out the genetic components of relatively rare conditions — such as Parkinson's disease or specific types of cancer — that affect only 1 % to 5 % of the population, comments behavioral geneticist Matthew McGue of the University of Minnesota, Twin Cities, who is not directly involved in the consortium.

The researchers predicted that the TRPC5 mechanism might play a similar role in other types of progressive kidney disease — even if, in those cases, the damaging feedback loop was kickstarted from chronic disorders such as high blood pressure, rather than a specific genetic mutation.

iPSCs directed to differentiate into specific cell types offer the possibility of a renewable source of replacement cells and tissues to treat ailments, including Parkinson's disease, spinal cord injury, heart disease, diabetes, and arthritis.

It's hoped this latest insight will lead to the widespread use of antigen - specific immunotherapy as a treatment for many autoimmune disorders, including multiple sclerosis (MS), type 1 diabetes, Graves» disease and systemic lupus erythematosus (SLE).

«Since MCR works by targeting specific DNA sequences, in cases where diseased cells have altered DNA as in HIV - infected individuals or some types of cancer, MCR - based methods should be able to distinguish diseased from healthy cells and then be used to selectively either destroy or modify the diseased cells.»

The research ideas you develop at the workshop should: • Lead to the significant advancement of our understanding of sensor technologies suitable for liquid biopsy • Consider the practical challenges of low volume liquid usually taken for analysis and the inconsistency of sample preparation across point of care sites • Prioritise biomarkers with high specificity for cancer or even for multiple cancer types, including markers specific to cancers that will become aggressive as opposed to non-lethal disease

While it is generally accepted that MSC are mostly quiescent during postnatal life, MSCs in different niches can presumably differentiate into the specific cells of closely related niches during physiological turnover, injury or disease, as shown for other stem cell types (e.g., muscle satellite cells).

This type of targeted dosing could make it possible to treat diseases that affect very specific brain circuits, without interfering with the normal function of the rest of the brain, the researchers say.

By understanding how certain brain cells are either vulnerable or resistant to neurodegenerative diseases, the lab has also discovered specific «profiles» of vulnerable cell types, thus advancing neuroprotective strategies for Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis (ALS).

He has developed novel cellular models of neurological diseases (schizophrenia, MS, autism, Alzheimer's, Parkinson's) using human induced pluripotent stem cells (iPSCs) derived from donor patients and differentiated to specific neuronal cell types.

Previously, he worked in the laboratories of Dr. Paul Greengard and Dr. Myriam Heiman, utilizing similar cutting - edge cell - type specific techniques to investigate pathology of Huntington's disease model in mice.

Inclusion Criteria: • Availability of tumor tissue for mesothelin expression testing • Histologically - confirmed, mesothelin - expressing metastatic or advanced non-metastatic disease (tumour type specific inclusion criteria) • At least one measurable lesion according to either Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 or International Thymic Malignancy Interest Group (ITMIG) modified RECIST 1.1 as applicable • Adequate bone marrow, liver, renal and coagulation function • Left ventricular ejection fraction (LVEF) ≥ 50 % of the lower limit of normal (LLN) according to local institutional ranges • Eastern Cooperative Oncology Group (ECOG) 0 or 1 Exclusion Criteria: • More than one prior anti - tubulin / microtubule agent • Corneal epitheliopathy or any eye disorder that may predispose the patients to this condition • Symptomatic Central nervous system (CNS) metastases and / or carcinomatous meningitis • Contraindication to both CT and MRI contrast agents • Active hepatitis B or C infection • Pregnant or breast - feeding patients • Tumor type specific exclusion criteria

This work is based on his previous research showing that a specific type of neuron that dies in Parkinson's disease is more vulnerable to problems in mitochondrial fission.

Ultimately, we use all this information to establish innovative culture techniques for generating unlimited neural stem cell sources for the derivation of specific types of clinically relevant neuronal or glial cells, for their use in disease modelling and drug discovery platforms, and towards refining their efficacy for future cell replacement - based therapy.

This type of testing is currently offered to individuals who have a family history of a genetic disease, people in certain ethnic groups with an increased risk of specific genetic diseases (population screening), and people concerned about their risk of having a child with a genetic disease.

Our objective is to generate a resource that facilitates research into human immune - related diseases by creating a comprehensive database of cell type - and allele - specific epigenomic and transcriptomic data for the immunology community.

We also performed subgroup meta - analyses by type of prevention (primary v secondary: in this study, trials involving healthy populations or patients with any specific disease except for cardiovascular disease were classified as primary prevention trials, and trials involving patients with cardiovascular disease were classified as secondary prevention trials), type of supplement by quality and dose (each supplement, vitamins only, antioxidants only, or antioxidants excluding vitamins), type of outcome (cardiovascular death, angina, fatal or non-fatal myocardial infarction, stroke, or transient ischaemic attack), type of outcome in each supplement, type of study design (randomised, double blind, placebo controlled trial v open label, randomised controlled trial), methodological quality (high v low), duration of treatment (< 5 years v ≥ 5 years), funding source (pharmaceutical industry v independent organisation), provider of supplements (pharmaceutical industry v not pharmaceutical industry), type of control (placebo v no placebo), number of participants (≥ 10000 v < 10000), and supplements given singly or in combination with other vitamin or antioxidant supplements by quality.

Using red blood cells modified to carry disease - specific antigens, a team of scientists from Whitehead Institute and Boston Children's Hospital have prevented and alleviated two autoimmune diseases — multiple sclerosis (MS) and type 1 diabetes — in early stage mouse models.

CReM's research using induced pluripotent stem cells (iPSCs), which self - renew indefinitely as undifferentiated cells that become specific adult cell types, has helped create an inexhaustible source of disease - or patient - specific stem cells.

But the type of science that instead aims to fill gaps in our understanding of the world — known as «basic» or «foundational» research — doesn't focus on specific applications, like a disease cure or a drought - resistant crop, so no one can predict the real - world impact of any individual line of inquiry.

To overcome these hurdles, Bhatia and her team reprogrammed human skin cells into induced pluripotent stem cells (iPSCs)-- embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease.

The Cancer Gene Census (CGC) database contains 547 such gene across various cancer types.5 Remarkably, few driver genes having specific point mutations appear to be sufficient to rewire signalling networks in cancer, 1 which at the same time shows that — at least from the mutational side — cancer does not consist of an «infinite» number of different diseases, and in many cases treatment options targeted against driver genes might be transferred from one case to the next.

What's more, the evidence suggests that there are certain lifestyle changes that might help, and there are other types of treatments that address specific symptoms (rather than the underlying cause of the disease) that may make life a little easier for people with Alzheimer's.

What makes the oats a detox superstar is their specific dietary fiber type, called beta - glucan, with exceptional benefits like lowering the risk of cardiovascular disease by lowering the bad cholesterol levels, stabilizing blood sugar levels, reducing the risk of Type 2 diabetes, and for lowering the risk of breast cancer for wotype, called beta - glucan, with exceptional benefits like lowering the risk of cardiovascular disease by lowering the bad cholesterol levels, stabilizing blood sugar levels, reducing the risk of Type 2 diabetes, and for lowering the risk of breast cancer for woType 2 diabetes, and for lowering the risk of breast cancer for women.

Refined processed carbohydrates are the major cause of weight gain, obesity, specific skin conditions, and many diet related diseases including heart disease, hypertension, insulin resistance, type 2 diabetes, some cancers, and obesity.

The common identifying factor in most autoimmune diseases is a destructive processes called inflammation which will eventually cause the destruction of cells and tissues specific to the type of auto - immune disease he person has.

Although it put a strain on her training, she addressed the disease with her doctor — who initially tried to treat it solely through medication — by actively tracking her nutrition and following a VERY specific type of nutritional strategy (while being monitored by her doctor).

But in autoimmune disease, the body creates a specific type of antibodies called autoantibodies — which end up being used by the body to attack itself.

The immune system is made up of a team of different types of cells that, while each having their own specific function, work together to protect the body from foreign invaders: B - cells produce antibodies; T - cells conduct surveillance for potentially dangerous molecules and kills dangerous cells such as disease - causing bacteria; and macrophages are the scavenger cells of your body acting like garbage trucks, cleaning up residue and removing potentially dangerous substances.

Risk of coronary heart disease is one of the specific types of cardiovascular risks that has been shown to be reduced by regular intake of garbanzo beans and other legumes.

Specific ailments, such as arthritis, kidney disease, liver disease, etc, may require a specific type Specific ailments, such as arthritis, kidney disease, liver disease, etc, may require a specific type specific type of food.