Sentences with phrase «specific type of tissue»

As time passes and the cells start dividing further and further, they start specializing into becoming a specific type of tissue which has a specific function, thus forming all the different parts that comprise a human.

Next - generation «designer matrices» such as hybrid polyethylene glycol hydrogels or microengineered collagen scaffolds, combined with a well - defined set of laminins, may better fulfill the niche requirements of organoids and may be customized for a specific type of tissue / organoid (2,6).

A defining property of all stem cells is that when they divide into two new cells, they can form both stem cells and differentiated cells (cells on their way to becoming a specific type of tissue).

Using gene techniques to promote growth of specific types of tissues would be a major step forward in the ability to perform truly regenerative surgery.

Not exact matches

Using patient's own tissue and specific combination of reprogramming factors, skin fibroblasts are successfully converted to cell type that... Continue reading Breakthrough Device Looks to Heal Organs

It is a type of branched DNA ISH that uses pairs of «Z - probes,» which are highly specific to target genes, but also small enough to easily diffuse into the tissues under study.

Current thinking regarding type III hypersensitivity is that immune cells within tissues sense the presence of these immune complexes (ICs) through specific receptor molecules and release inflammatory factors called cytokines that activate the endothelial cells lining adjacent blood vessels to promote the recruitment of neutrophils.

On the other hand, on a molecular level, researchers find that there is a specific response tied to the hormone levels within the tissue, meaning that the plant could tell which type of stress it is being subjected to, and therefore induce the most suitable physiological responses to fight it.

One such mechanism is «DNA methylation,» which shuts off or silences parts of the genetic code to form a specific pattern that identifies each tissue type.

In Arabidopsis, as in most plants, there is a specific zone near the tip of the root where stem cells transition from a stage of proliferation to one where they differentiate into specific tissue types.

Techniques enabling the isolation of specific cell populations have advanced our ability to identify and characterize niche cell types which may be used to replace or engineer cells / tissue.

One theory has been that calorie restriction slows age - related degeneration and enables more efficient tissue function by influencing the integrity and activity of adult stem cells, the precursor cells that dwell within specific tissues and give rise to the diversity of cell types that compose that tissue.

Some tissues show a natural contrast on MRI, but for some specific types of imaging, patients are administered a MRI contrast agent to enhance the difference between the target area and the rest of the body.

While both species carry a core group of similar programs to regulate gene activity, the researchers found that differences appeared in specific tissue and cell types.

This type of imaging uses a radioactive tracer to look for chemical signs of disease in specific tissues.

Different types of tumors show a preference for specific organs and tissues; circulating breast cancer cells, for example, are likely to take root in bones, lungs, and the brain.

iPSCs directed to differentiate into specific cell types offer the possibility of a renewable source of replacement cells and tissues to treat ailments, including Parkinson's disease, spinal cord injury, heart disease, diabetes, and arthritis.

Three types of structural variations were visible in the tissue - specific endothelial cell lines (Fig. 2) ⇓.

His laboratory investigates how cell type specific differences in protein synthesis and homeostasis promote tissue regeneration and suppress the development of cancer.

Following the delineation of some of the basic principles behind bud formation, the researchers then whether they could extend this strategy beyond the liver, and create other organ buds using tissue specific cell types.

With the recent development of transgenic mouse models, which allow labelling and manipulation of specific cell types, more and more emphasis has been placed on the tissue scale: How does the collective behavior of many cells gives rise to the architecture that is characteristic for given kind of tissue?

In doing so, specific cell types may activate immune responses to fine tune cell - fate decisions at the organismal level; for instance, DNA damage in germ cells induces an innate immune response in worms that promotes endurance of somatic tissues to allow delay of progeny production when germ cells are hit by DNA damage.

The collection of protocols includes the isolation and maintenance of stem cells from various species using «conventional» and novel methods, such as derivation of ES cells from single blastomeres, differentiation of stem cells into specific tissue types, isolation and maintenance of somatic stem cells, stem cell - specific techniques and approaches to tissue engineering using stem cell derivatives.

Luckily, different cell types tend to have different things on their surfaces, which play particular parts in their specialized roles in the tissue, so it is a matter of identifying and targeting cell - surface markers that are specific to these abnormal cell types.

During development, cells have to integrate different types of molecular and physical information to proliferate, and to make decisions such as whether to maintain pluripotency or trigger differentiation and acquire specialisation for tissue - specific functions.

Inclusion Criteria: • Availability of tumor tissue for mesothelin expression testing • Histologically - confirmed, mesothelin - expressing metastatic or advanced non-metastatic disease (tumour type specific inclusion criteria) • At least one measurable lesion according to either Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 or International Thymic Malignancy Interest Group (ITMIG) modified RECIST 1.1 as applicable • Adequate bone marrow, liver, renal and coagulation function • Left ventricular ejection fraction (LVEF) ≥ 50 % of the lower limit of normal (LLN) according to local institutional ranges • Eastern Cooperative Oncology Group (ECOG) 0 or 1 Exclusion Criteria: • More than one prior anti - tubulin / microtubule agent • Corneal epitheliopathy or any eye disorder that may predispose the patients to this condition • Symptomatic Central nervous system (CNS) metastases and / or carcinomatous meningitis • Contraindication to both CT and MRI contrast agents • Active hepatitis B or C infection • Pregnant or breast - feeding patients • Tumor type specific exclusion criteria

Researchers had developed the technologies needed to create organoids years before — how to grow cells in culture, how to isolate stem cells from human tissue, and how to coax the stem cells, undifferentiated and immature, to become specific types of cells at later stages of development.

Researchers quickly grasped, with a frenzied enthusiasm, how remotely controlling the activity of a specific neuronal type in a fine temporal scale, whether in culture, tissue or freely moving animals, could apply to a vast array of questions.

Many of the novel motifs displayed occupancy patterns that were highly cell - type - specific, similar to the patterns observed among major developmental and tissue - specific regulators.

Professor Zhou explained: «We built a database of epigenetic markers, specifically methylation patterns, which are common across many types of cancer and also specific to cancers originating from specific tissue, such as the lung or liver.

Living tissues are composed of many cell types that are arranged in a very specific order.

Since joining Gladstone, McDevitt's lab has created a new method to generate three - dimensional clusters of specific types of cells that can be used to form and maintain tissue constructs.

Finally, the strategy applied here for selective delivery of MK801 can be extended to other small molecules for use in brain tissue (Tian et al., 2012), allowing for an approach that combines chemistry, molecular genetics, and neurobiology to dissect cell signaling pathways in specific cell types in the central nervous system.

Oxidative Free Unstable Radicals are a specific type of molecule that can damage muscle tissue, fats, and DNA within cells.

Because this type of tissue is so specific, even when it's outside the uterus in the case of endo, it still builds and swells with blood.

The common identifying factor in most autoimmune diseases is a destructive processes called inflammation which will eventually cause the destruction of cells and tissues specific to the type of auto - immune disease he person has.

More Efficient Use of Your Time Modern Class IV lasers employ sophisticated software that helps technicians apply a tailored protocol that adjusts the light intensity, wavelength, and pulse frequency based on the specific tissue - types they are treating, but all behind the scenes of an easy - to - use, touchscreen user interface.

ACT - activated clotting time (bleeding disorders) ACTH - adrenocorticotropic hormone (adrenal gland function) Ag - antigen test for proteins specific to a disease causing organism or virus Alb - albumin (liver, kidney and intestinal disorders) Alk - Phos, ALP alkaline phosphatase (liver and adrenal disorders) Allergy Testing intradermal or blood antibody test for allergen hypersensitivity ALT - alanine aminotransferase (liver disorder) Amyl - amylase enzyme — non specific (pancreatitis) ANA - antinuclear antibody (systemic lupus erythematosus) Anaplasmosis Anaplasma spp. (tick - borne rickettsial disease) APTT - activated partial thromboplastin time (blood clotting ability) AST - aspartate aminotransferase (muscle and liver disorders) Band band cell — type of white blood cell Baso basophil — type of white blood cell Bile Acids digestive acids produced in the liver and stored in the gall bladder (liver function) Bili bilirubin (bile pigment responsible for jaundice from liver disease or RBC destruction) BP - blood pressure measurement BUN - blood urea nitrogen (kidney and liver function) Bx biopsy C & S aerobic / anaerobic bacterial culture and antibiotic sensitivity test (infection, drug selection) Ca +2 calcium ion — unbound calcium (parathyroid gland function) CBC - complete blood count (all circulating cells) Chol cholesterol (liver, thyroid disorders) CK, CPK creatine [phospho] kinase (muscle disease, heart disease) Cl - chloride ion — unbound chloride (hydration, blood pH) CO2 - carbon dioxide (blood pH) Contrast Radiograph x-ray image using injected radiopaque contrast media Cortisol hormone produced by the adrenal glands (adrenal gland function) Coomb's anti- red blood cell antibody test (immune - mediated hemolytic anemia) Crea creatinine (kidney function) CRT - capillary refill time (blood pressure, tissue perfusion) DTM - dermatophyte test medium (ringworm — dermatophytosis) EEG - electroencephalogram (brain function, epilepsy) Ehrlichia Ehrlichia spp. (tick - borne rickettsial disease) EKG, ECG - electrok [c] ardiogram (electrical heart activity, heart arryhthmia) Eos eosinophil — type of white blood cell Fecal, flotation, direct intestinal parasite exam FeLV Feline Leukemia Virus test FIA Feline Infectious Anemia: aka Feline Hemotrophic Mycoplasma, Haemobartonella felis test FIV Feline Immunodeficiency Virus test Fluorescein Stain fluorescein stain uptake of cornea (corneal ulceration) fT4, fT4ed, freeT4ed thyroxine hormone unbound by protein measured by equilibrium dialysis (thyroid function) GGT gamma - glutamyltranferase (liver disorders) Glob globulin (liver, immune system) Glu blood or urine glucose (diabetes mellitus) Gran granulocytes — subgroup of white blood cells Hb, Hgb hemoglobin — iron rich protein bound to red blood cells that carries oxygen (anemia, red cell mass) HCO3 - bicarbonate ion (blood pH) HCT, PCV, MHCT hematocrit, packed - cell volume, microhematocrit (hemoconcentration, dehydration, anemia) K + potassium ion — unbound potassium (kidney disorders, adrenal gland disorders) Lipa lipase enzyme — non specific (pancreatitis) LYME Borrelia spp. (tick - borne rickettsial disease) Lymph lymphocyte — type of white blood cell MCHC mean corpuscular hemoglobin concentration (anemia, iron deficiency) MCV mean corpuscular volume — average red cell size (anemia, iron deficiency) Mg +2 magnesium ion — unbound magnesium (diabetes, parathyroid function, malnutrition) MHCT, HCT, PCV microhematocrit, hematocrit, packed - cell volume (hemoconcentration, dehydration, anemia) MIC minimum inhibitory concentration — part of the C&S that determines antimicrobial selection Mono monocyte — type of white blood cell MRI magnetic resonance imaging (advanced tissue imaging) Na + sodium ion — unbound sodium (dehydration, adrenal gland disease) nRBC nucleated red blood cell — immature red blood cell (bone marrow damage, lead toxicity) PCV, HCT, MHCT packed - cell volume, hematocrit, microhematocrit (hemoconcentration, dehydration, anemia) PE physical examination pH urine pH (urinary tract infection, urolithiasis) Phos phosphorus (kidney disorders, ketoacidosis, parathyroid function) PLI pancreatic lipase immunoreactivity (pancreatitis) PLT platelet — cells involved in clotting (bleeding disorders) PT prothrombin time (bleeding disorders) PTH parathyroid hormone, parathormone (parathyroid function) Radiograph x-ray image RBC red blood cell count (anemia) REL Rocky Mountain Spotted Fever / Ehrlichia / Lyme combination test Retic reticulocyte — immature red blood cell (regenerative vs. non-regenerative anemia) RMSF Rocky Mountain Spotted Fever SAP serum alkaline phosphatase (liver disorders) Schirmer Tear Test tear production test (keratoconjunctivitis sicca — dry eye,) Seg segmented neutrophil — type of white blood cell USG Urine specific gravity (urine concentration, kidney function) spec cPL specific canine pancreatic lipase (pancreatitis)-- replaces the PLI test spec fPL specific feline pancreatic lipase (pancreatitis)-- replaces the PLI test T4 thyroxine hormone — total (thyroid gland function) TLI trypsin - like immunoreactivity (exocrine pancreatic insufficiency) TP total protein (hydration, liver disorders) TPR temperature / pulse / respirations (physical exam vital signs) Trig triglycerides (fat metabolism, liver disorders) TSH thyroid stimulating hormone (thyroid gland function) UA urinalysis (kidney function, urinary tract infection, diabetes) Urine Cortisol - Crea Ratio urine cortisol - creatine ratio (screening test for adrenal gland disease) Urine Protein - Crea Ratio urine protein - creatinine ratio (kidney disorders) VWF VonWillebrands factor (bleeding disorder) WBC white blood cell count (infection, inflammation, bone marrow suppression)