Sentences with phrase «specific type of tumor»

The histopathology report will give your veterinarian the diagnosis of the specific type of tumor, and that helps to indicate how it is likely to behave.

The drug represents a new class of treatments that are made to attack a specific type of tumor.

Biopsy, samples removed from the tumor and examined to confirm diagnosis of a specific type of tumor

Although scientists have examined insulin action in tumors for years, the ability to knock out the insulin receptor in specific types of tumor cells adds a level of sophistication to these investigations, Rask - Madsen emphasizes.

Information on specific types of tumors can be found below.

Not exact matches

So research teams began souping up various types of immune cells and even targeting them to specific protein markers on tumors.

«Shifting bacterial communities in the stomach may influence cancer risk: Microbe changes linked with specific conditions could explain differences in risk and type of tumor.»

«Just as normal cells with the same genome differentiate into many different cell types, a single tumor characterized by specific genetic mutations can contain many different types of cells — stem - like and more differentiated cells — with the difference being rooted in their epigenetic information.

Most cancer vaccines developed to date have been designed to recognize and attack a specific known molecule — such as a cell - surface receptor — that is likely to be found on cancerous cells in any patient with that type of tumor.

«Each tumor type may acquire a unique set of capabilities that may provide tumor - specific growth and survival advantages, which may need to be determined for each kind of cancer.

In earlier studies involving animal models and human cancer cell lines, researchers found that breast cancer spreads when three specific cells are in direct contact: an endothelial cell (a type of cell that lines the blood vessels), a perivascular macrophage (a type of immune cell found near blood vessels), and a tumor cell that produces high levels of Mena, a protein that enhances a cancer cell's ability to spread.

This is important because tumors are not all alike and some types of tumor cells may respond differently to a specific drug than others, Skala pointed out.

«Not only did we find that LIGHT expression promoted tumor regression, upon further study we also identified the specific type of T - cell — CD8 — that was responsible for shrinking the tumor,» Maker said.

A relatively new biomarker called prostate - specific membrane antigen (PSMA) is the bullseye for three new magnetic resonance imaging (MRI) agents that bind to the protein in not only prostate cancer, but a range of tumor types, according to research unveiled at the 2015 annual meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI).

Another possibility that Irvine's lab is working on is developing treatments that could be used against tumors even when scientists don't know of a specific vaccine target for that type of tumor.

Different types of tumors show a preference for specific organs and tissues; circulating breast cancer cells, for example, are likely to take root in bones, lungs, and the brain.

Confirmation of the biomarkers in other cancer types will facilitate further characterization and validation to provide mechanistic understanding of how and why these specific gene - targets become modulated to accentuate or inhibit tumor metastasis.

However, despite this success, the use of immunotherapy remains limited by the scarcity of tumor - specific antigens — substances that can trigger an immune system response to a particular type of cancer.

Baltimore, Md. (Embargoed until 12:30 pm EDT on Monday, June 8)-- A relatively new biomarker called prostate - specific membrane antigen (PSMA) is the bullseye for three new magnetic resonance imaging (MRI) agents that bind to the protein in not only prostate cancer, but a range of tumor types, according to research unveiled at the 2015 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI).

The MIT team is now testing this approach to treat tumors in mice and is also working on ways to deliver the antibodies to specific types of cells.

«Our results clearly demonstrate a significant, although unexpected, role for specific gut bacteria in enhancing the immune system's response to melanoma and possibly many other tumor types,» said study director Thomas Gajewski, MD, PhD, professor of medicine and pathology at the University of Chicago.

«But we know that tumors generally develop from a single cell or a small number of cells of a specific cell type, which is one of the major determinants of the characteristics of tumor cells,» explains postdoctoral researcher and co-author Dinorah Friedmann - Morvinski.

So, the researchers forced expression of a dominant - negative TGF - β receptor type 2 (DNRII) onto LMP - specific T cells (DNRII - LSTs) that were specially designed to seek out and destroy proteins derived from the Epstein - Barr virus expressed by the tumor cells.

To get there, researchers will need to resolve certain obstacles associated with CAR - T, including further customization of the technology to recognize specific / other tumor types, and predicting and limiting cross-reactivity, where CAR - T immune cells start attacking healthy cells as well.

The median time to response was 1.8 months, and responses occurred regardless of tumor type, patient age, or specific TRK fusion characteristics.

Inclusion Criteria: • Availability of tumor tissue for mesothelin expression testing • Histologically - confirmed, mesothelin - expressing metastatic or advanced non-metastatic disease (tumour type specific inclusion criteria) • At least one measurable lesion according to either Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 or International Thymic Malignancy Interest Group (ITMIG) modified RECIST 1.1 as applicable • Adequate bone marrow, liver, renal and coagulation function • Left ventricular ejection fraction (LVEF) ≥ 50 % of the lower limit of normal (LLN) according to local institutional ranges • Eastern Cooperative Oncology Group (ECOG) 0 or 1 Exclusion Criteria: • More than one prior anti - tubulin / microtubule agent • Corneal epitheliopathy or any eye disorder that may predispose the patients to this condition • Symptomatic Central nervous system (CNS) metastases and / or carcinomatous meningitis • Contraindication to both CT and MRI contrast agents • Active hepatitis B or C infection • Pregnant or breast - feeding patients • Tumor type specific exclusion critumor tissue for mesothelin expression testing • Histologically - confirmed, mesothelin - expressing metastatic or advanced non-metastatic disease (tumour type specific inclusion criteria) • At least one measurable lesion according to either Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 or International Thymic Malignancy Interest Group (ITMIG) modified RECIST 1.1 as applicable • Adequate bone marrow, liver, renal and coagulation function • Left ventricular ejection fraction (LVEF) ≥ 50 % of the lower limit of normal (LLN) according to local institutional ranges • Eastern Cooperative Oncology Group (ECOG) 0 or 1 Exclusion Criteria: • More than one prior anti - tubulin / microtubule agent • Corneal epitheliopathy or any eye disorder that may predispose the patients to this condition • Symptomatic Central nervous system (CNS) metastases and / or carcinomatous meningitis • Contraindication to both CT and MRI contrast agents • Active hepatitis B or C infection • Pregnant or breast - feeding patients • Tumor type specific exclusion criTumor type specific exclusion criteria

Miroslav Machala, head of the Department of Chemistry and Toxicology at the Veterinary Research Institute in the Czech Republic, said in an emailed response that, while these specific compounds lack data, these types of PCBs could potentially promote tumor growth as well.

The resulting DNA copy number variation and patterns of chromosome loss and gain are tumor - type specific, suggesting differential selective pressures on the two tumor cell types.

They looked for correlations between specific mutations in the tumor cells and the composition of the tumor microbiome — the types of bacteria present in the tumor's immediate environment and their relative abundance — and found relationships between the two.

This confirmed that the gene regulatory switch is highly specific to one cell type, monocytes and that tumor cell invasion in the absence of this population had nothing to do with deregulated macrophage activity.

In fact, specific mutations in tumor cells were associated with the presence of specific types of bacteria in the microbiome.

National Cancer Institute and ECOG - ACRIN announce the July 2015 opening of the NCI - MATCH / EAY131 trial, a multi-arm phase II precision medicine study that seeks to determine whether targeted therapies for people whose tumors have specific gene mutations will be effective regardless of cancer type.

Different types of tumors are formed by specific kinds of microbes.

Primary treatment for specific tumor types Indications for the use of external beam radiation therapy for the primary treatment of tumors has expanded significantly with the emergence of SRS for pets.

Indications for radiation therapy (RT) include the primary treatment of specific tumor types, such as nasal tumors and brain tumors, adjuvant treatment of incompletely excised tumors, and palliation to improve quality of life for patients with non-resectable or advanced cancers.

Cryotherapy which involves freezing the skin tumors can be successful for specific types of carcinomas.

The scientists are also continuing to investigate mutations that occur in the tumors themselves (somatic mutations) and are profiling the susceptibility of specific tumor types to various chemotherapy compounds, which may lead to improved therapy options.

A small sample of the tumor is removed to determine the specific tumor type.

A specific tumor type can be suspected from its appearance on a CT or MRI, but can only be definitively identified by taking a sample of the tumor, either at surgery or by biopsy.

The prognosis for pets diagnosed with intestinal tumors will depend on a variety of factors, including the specific tumor type, the stage of the disease and whether the cancer has spread to other organs.

See below for information on specific types of cancer such as anal sac and colorectal tumors.

In rare cases a tumor called fibrosarcoma may develop at the injection site, however, this has been found to develop in only specific individuals who are genetically predisposed to form these tumors secondary to any type of infection or inflammation.

One of the confusing issues with tumor submission is that specific diagnosis of the tumor type and submitting a sample to the repository are two different submissions.