Sentences with phrase «specific types of cells»

Additional processing, such as softening bones so they can be sectioned easily, or applying special stains or markers to identify specific types of cells, are occasionally needed.

Progesterone also signals cells to differentiate, or develop into specific types of cells.

Since joining Gladstone, McDevitt's lab has created a new method to generate three - dimensional clusters of specific types of cells that can be used to form and maintain tissue constructs.

Researchers had developed the technologies needed to create organoids years before — how to grow cells in culture, how to isolate stem cells from human tissue, and how to coax the stem cells, undifferentiated and immature, to become specific types of cells at later stages of development.

The MIT team is now testing this approach to treat tumors in mice and is also working on ways to deliver the antibodies to specific types of cells.

Development is thought to go just one way: Stem cells differentiate into specific types of cells, but the reverse isn't supposed to happen.

Neuroscientists at Cold Spring Harbor Laboratory (CSHL) have mobilized advanced imaging and computational methods to comprehensively map — «count» — the total populations of specific types of cells throughout the mouse brain.

Zygotes generate specific types of cells in an orderly progression.

The study, published in Nature Communications, builds on previous observations from the same team who found that a specific type of cells regulate antibody production.

«We've shown that a specific type of these cells, known as follicular helper T (Tfh) cells are not only necessary, but are a limiting factor that differentiates between an average and a potent antibody response to HIV,» says Crotty, a scientific collaborator with the Center for HIV / AIDS Vaccine Immunology & Immunogen Discovery (CHAVI - ID), a major research consortium led by The Scripps Research Institute.

This seemingly impossible task led most previous studies to examine randomly selected neurons or focus on a specific type of cell.

To tap embryonic stem cells» therapeutic potential, researchers must learn how to coax them to become a specific type of cell that can then be transplanted into the body.

The specific type of cells the researchers in the new Nature Medicine paper looked at, and identified as giving rise to suPAR, are bone marrow GR - 1lo, Sca1 + immature myeloid cells.

Now, Professor Martin and colleagues have discovered that in response to specific types of cell damage, Parkin can trigger the self - destruction of «injured» nerve cells by switching on a controlled process of «cellular suicide» called apoptosis.

By controlling the proteins that wrap the genes, scrawny can silence genes that would otherwise cause a generalized cell to differentiate into a specific type of cell, such as a skin or intestinal cell.

The first step was determining how to obtain healthy samples of this specific type of cell.

On the heels of identifying the specific type of cell that gives rise to retinoblastoma, RPB - funded researchers at St. Jude Children's Research Hospital are solving a long - standing mystery about how the eyes of vertebrates develop and how a rare pediatric eye cancer progresses.

On the heels of identifying the specific type of cell that gives rise to retinoblastoma, RPB - funded researchers at St. Jude Children's Research Hospital are solving a long - standing mystery about how the eyes...

A new study conducted by researchers at the Norwegian University of Science and Technology suggests that a specific type of cell known as a speed cell allow individuals to moderate how fast or how slow they move.

While lymphocytes are a specific type of cell within the blood, LSA is not restricted to the blood.

Not exact matches

So research teams began souping up various types of immune cells and even targeting them to specific protein markers on tumors.

The treatment is a type of so - called CAR T - cell therapy — taking a patient's own immune cells, called T cells, genetically manipulating them to attack specific proteins on cancer, and infusing them back into the patient.

Using patient's own tissue and specific combination of reprogramming factors, skin fibroblasts are successfully converted to cell type that... Continue reading Breakthrough Device Looks to Heal Organs

According to the American Pregnancy Association, the Rh factor is a specific type of protein on the surface of red blood cells.

In the direct reprogramming, the researchers exposed the adult skin cells to a specific mix of signaling molecules the scientists» past research had found would convert healthy skin cells directly into a type of brain cell called medium spiny neurons, without intermediate steps along the way.

While all cells in a specific organism share the identical DNA sequence, only a fraction of those genes are activated in a given cell type.

This cell - type - specific analysis was essential to demonstrate that there is a close interplay between epigenetic mechanisms and the spatial folding of the DNA in the cardiomyocytes» nucleus.

It is emerging that the chemical structure of RNA molecules is extensively modified by specific enzymes normally present in our cells, which are commonly found to be altered in severe medical syndromes and various types of cancers.

Each of us develops from an unspecialized single cell into hundreds of different specific cell types.

Therefore, it is essential that we learn how specific types of chemical modifications normally regulate RNA function in our cells, in order to understand how dysregulation of this process contributes to human disease, says Cristian Bellodi.

After 24 days the cells had developed surface proteins that identified them as specific types of lung cell, including alveolar cells, which allow the exchange of gases, and cilia, which expel bacteria and dirt (Respiratory Research, DOI: 10.1186 / 1465-9921-10-105).

«If we fed the fish a specific type of fat, our technique allowed us to determine into what molecules these lipids were reassembled after they were broken down in the small intestine and in which organs and cells these molecules ended up,» Farber explained.

Bioengineers at the University of California, San Diego have proven that when it comes to guiding stem cells into a specific cell type, the stiffness of the extracellular matrix used to culture them really does matter.

The most common type of skin lymphoma is caused by the fact that specific immune cells — CD4 - T - lymphocyttes — turn into cancer cells.

«Just as normal cells with the same genome differentiate into many different cell types, a single tumor characterized by specific genetic mutations can contain many different types of cells — stem - like and more differentiated cells — with the difference being rooted in their epigenetic information.

«The challenge has been how to direct certain therapies designed to manipulate genes of interest in specific cells without developing a specific drug carrier for each specific cell type.

The two - part approach netted a set of mutations seen only at relapse that enabled the team to sift and sort leukemic and normal stem cells using tools developed in the Dick lab a few years ago to zero in on specific cell types fated to relapse.

Researchers at Penn State have combined the two approaches by taking biodegradable polymer nanoparticles encapsulated with cancer - fighting drugs and incorporating them into immune cells to create a smart, targeted system to attack cancers of specific types.

Other researchers have already loaded hollow origami structures with drugs to target specific types of cancer cells, created DNA «robots» that walk across surfaces, and mimicked the shape of viruses.

To do so they focused on keratinocytes, a specific type of skin cells with a key role in psoriasis because of their abnormal growth and ability to produce large amounts of inflammation promoting factors.

Progenitor cells are early descendants of stem cells that can differentiate into one or more specific cell types.

Identifying changes in the mitochondrial DNA in PPN cholinergic neurons has the potential to allow the development of more effective treatments targeted to specific cell - types.

Most cancer vaccines developed to date have been designed to recognize and attack a specific known molecule — such as a cell - surface receptor — that is likely to be found on cancerous cells in any patient with that type of tumor.

«Only by understanding the complexities of what happens in specific cell - types found in specific areas of the brain during this disease can targeted treatments for Parkinson's disease be produced.»

To better understand how this abnormal distribution of B cell types in people with uncontrolled HIV affected their immune response to the virus, researchers compared HIV - specific antibodies derived from both TLM and RM B cells.

«Unlike previous studies we isolated different immune cell types from the actual site of disease to determine whether specific subsets of immune cells (specific T cell groups) have equal sensitivity to vitamin D.»

The Karlssons were referred to the Karolinska University Hospital in Stockholm, where physicians proposed a radical strategy: Harvest a specific type of stem cell from the liver of an aborted fetus and infuse it through the umbilical vein into the fetus that Madeleine was carrying.

One of the many mysteries of stem cells is how they morph from a universal cell type, full of possibility, into one that's tailored for a specific job.

Luster's team hopes to further investigate the characteristics of joints that underlie the critical role of C5a in initiating type III hypersensitivity and whether specific molecules expressed on endothelial cells lining joints play a role in transporting C5a and chemokines from the joint space into adjacent blood vessels.

This is particularly important as it indicates the method can be used in a variety of cell types to create disease models and contribute to the discovery of new disease - specific therapeutics.