Sentences with phrase «specific types of stem cells»

The Karlssons were referred to the Karolinska University Hospital in Stockholm, where physicians proposed a radical strategy: Harvest a specific type of stem cell from the liver of an aborted fetus and infuse it through the umbilical vein into the fetus that Madeleine was carrying.

Not exact matches

Bioengineers at the University of California, San Diego have proven that when it comes to guiding stem cells into a specific cell type, the stiffness of the extracellular matrix used to culture them really does matter.

«Just as normal cells with the same genome differentiate into many different cell types, a single tumor characterized by specific genetic mutations can contain many different types of cells — stem - like and more differentiated cells — with the difference being rooted in their epigenetic information.

The two - part approach netted a set of mutations seen only at relapse that enabled the team to sift and sort leukemic and normal stem cells using tools developed in the Dick lab a few years ago to zero in on specific cell types fated to relapse.

Progenitor cells are early descendants of stem cells that can differentiate into one or more specific cell types.

One of the many mysteries of stem cells is how they morph from a universal cell type, full of possibility, into one that's tailored for a specific job.

The blood ancestors are usually called hematopoietic stem cells; these cells were classically defined as a specific category of multipotent cells at the top of the hierarchy that can differentiate into any blood cell type by following a deterministic program.

The transplanted stem cells differentiated to different types of cells with variable level of maturation, specific for the nervous system.

In Arabidopsis, as in most plants, there is a specific zone near the tip of the root where stem cells transition from a stage of proliferation to one where they differentiate into specific tissue types.

«Use of induced pluripotent stem cell (iPSC) technology» — which involves taking skin cells from patients and reprogramming them into embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease — «makes it possible to model dementias that affect people later in life,» says senior study author Catherine Verfaillie of KU Leuven.

One theory has been that calorie restriction slows age - related degeneration and enables more efficient tissue function by influencing the integrity and activity of adult stem cells, the precursor cells that dwell within specific tissues and give rise to the diversity of cell types that compose that tissue.

During embryonic development, organ - specific cell types are formed from pluripotent stem cells, which can differentiate into all cell types of the human body.

Development is thought to go just one way: Stem cells differentiate into specific types of cells, but the reverse isn't supposed to happen.

To tap embryonic stem cells» therapeutic potential, researchers must learn how to coax them to become a specific type of cell that can then be transplanted into the body.

The researchers then attempted to see if the cells, which they labeled multipotent adult germline stem cells (maGSC), would differentiate into specific types of body cells.

They coated this scaffold with growth factors — chemical cues to goad stem cells into becoming specific cell types — then soaked the structure in a solution of stem cells extracted from Beyene's bone marrow.

A defining property of all stem cells is that when they divide into two new cells, they can form both stem cells and differentiated cells (cells on their way to becoming a specific type of tissue).

When the researchers added a specific bone morphogenetic protein called BMP4, as well as another signaling molecule called retinoic acid, to human embryonic stem cells, they got a mixture of two types of sensory interneurons.

The researchers also have yet to determine the specific recipe of growth factors that would coax stem cells to create other types of sensory interneurons.

First, a hair follicle contains epithelial cells — a cell type that lines the body's vessels and cavities — as well as a specific kind of adult stem cell called dermal papillae.

\ n \ n Unfortunately, the general public seems to be unaware of certain basic facts regarding stem cell research and the media contributes to this by frequently reporting on «stem cell» research and not being more specific as to the type of stem cell research that is producing results.

While it is generally accepted that MSC are mostly quiescent during postnatal life, MSCs in different niches can presumably differentiate into the specific cells of closely related niches during physiological turnover, injury or disease, as shown for other stem cell types (e.g., muscle satellite cells).

Characterized other proteins and pathways that modulate proliferation and differentiation of myogenic stem cells, hypertrophic growth of the heart, mitochondrial biogenesis and fiber type — specific gene expression in skeletal muscles.

Stem cells from fat have the ability to mature into other types of specific cells, including muscle, bone and cartilage, but how many other types is still unknown.

By: Sadhana Agarwal, Katherine L. Holton, Robert Lanza Differentiation of human embryonic stem cells (hESCs) to specific functional cell types can be achieved using methods that mimic in vivo embryonic developmental programs.

He has developed novel cellular models of neurological diseases (schizophrenia, MS, autism, Alzheimer's, Parkinson's) using human induced pluripotent stem cells (iPSCs) derived from donor patients and differentiated to specific neuronal cell types.

The collection of protocols includes the isolation and maintenance of stem cells from various species using «conventional» and novel methods, such as derivation of ES cells from single blastomeres, differentiation of stem cells into specific tissue types, isolation and maintenance of somatic stem cells, stem cell - specific techniques and approaches to tissue engineering using stem cell derivatives.

However, the further development this type of therapy requires a reliable source for the large amounts of homogenous functional patient - specific NK cells needed and this has led to the generation of NK cells from human induced pluripotent stem cells (iPSCs)[3].

Ultimately, we use all this information to establish innovative culture techniques for generating unlimited neural stem cell sources for the derivation of specific types of clinically relevant neuronal or glial cells, for their use in disease modelling and drug discovery platforms, and towards refining their efficacy for future cell replacement - based therapy.

We have recently developed the use of site - specific nucleases to genetically engineer human pluripotent stem cells, which can be maintained indefinitely and differentiated into any cell type of interest.

The major gains in behavioral recovery and neuronal survival achieved by pre-differentiation of glial precursors to specific, beneficial astrocytic cell types prior to transplantation stresses the need to consider such manipulations as a critical component in the optimization of stem / precursor cell transplantation based therapies.

Researchers had developed the technologies needed to create organoids years before — how to grow cells in culture, how to isolate stem cells from human tissue, and how to coax the stem cells, undifferentiated and immature, to become specific types of cells at later stages of development.

The three - dimensional organization of the genome represents a cell - type specific means to regulate gene transcription; however, we currently lack a detailed understanding of the architectural changes that occur during the generation of induced pluripotent stem cells (iPSCs) due to the inherent inefficiency of the reprogramming process [1].

Spermatogenesis in both species starts with spermatogonial stem cells located in a specific position of the tubule, attached to the apical end in fly and to basement membrane in mice, which move and progress into later stages of cell types in one direction, towards the basal end of the testis tubule in fly and towards the lumen in mice.

CReM's research using induced pluripotent stem cells (iPSCs), which self - renew indefinitely as undifferentiated cells that become specific adult cell types, has helped create an inexhaustible source of disease - or patient - specific stem cells.

To overcome these hurdles, Bhatia and her team reprogrammed human skin cells into induced pluripotent stem cells (iPSCs)-- embryonic - like stem cells capable of turning into other specific cell types relevant for studying a particular disease.

On Houston's Clear Thinkers, Tom Kirkendall ponders the view of cancer as tenaciously persistent and able to regenerate after apparently disappearing — driven by a specific cell type lurking within the cancer that is capable of dormancy, growth and infinite regeneration — a cancer «stem cell» in The Cancer Sleeper cell type lurking within the cancer that is capable of dormancy, growth and infinite regeneration — a cancer «stem cell» in The Cancer Sleeper cell» in The Cancer Sleeper CellCell