Because Ebola diagnostics and some therapeutics like vaccines are based on
the specific viral sequence, it is important for researchers to have the most up - to - date virus genome sequence possible.
Using a reverse - genetics system, in which
specific viral sequences are manipulated within the context of a full - length infectious clone of the virus, they have been defining the roles of particular viral components in influencing DENV and ZIKV infection in mice and human cells.
Not exact matches
An article published on June 26th in PLOS Pathogens now reports that a mini antibody called 3D8 scFv can degrade (or chew up)
viral DNA and RNA regardless of
specific sequences and protect mammalian cells and genetically manipulated mice against different viruses.
According to the previous study, the Cas13a enzyme can be programmed to target
specific sequences in
viral and bacterial cells and still remain active afterwards.