More recently, Mirkin lab has developed a novel version of
spherical nucleic acids, named Sticky - Flares (Briley et al., PNAS 112:9591 - 9595, 2015), which has also been patented for commercial use.
The miR - 182 was safely delivered to the tumors using
spherical nucleic acids, DNA and RNA arranged around a gold nanoparticle center.
They combined
spherical nucleic acids (SNAs, which are nanoscale globular forms of RNA) with a common commercial moisturizer to create a way to topically knock down a gene known to interfere with wound healing.
Not exact matches
The
spherical structure of the SNAs is the ideal architecture for delivering
nucleic acids into cells for gene regulation, Mirkin said.