Not exact matches
In most cases of
spinal cord injury, the loss of this link from the brain to the
locomotion center causes problems with walking.
The research group came up with bypassing the functioning brain and
locomotion center with the computer to compensate lost pathways as a way to enable individuals with
spinal cord injury to regain walking ability.
Neural networks in the
spinal cord,
locomotion center are capable of producing rhythmic movements, such as swimming and walking, even when isolated from the brain.
Moreover, some behaviors such as simple reflexes and basic
locomotion, can be executed under
spinal cord control alone.
Early in his career Grillner showed how these circuits in the mammalian
spinal cord generate periodic motor commands for the rhythmic movements involved in
locomotion - a process that demands the coordination of dozens of different muscles.
CSF - contacting neurons regulate
locomotion by relaying mechanical stimuli to
spinal circuits.
This type of neuroprosthesis works by engaging healthy
spinal circuits downstream from the injury site, producing step - like
locomotion in the hind limbs when stimulation is applied.
This was used to restore
locomotion in rats sustaining paralyzing
spinal cord injury.
The discovery of motor pattern generators, the neural network's underlying movements, in the
spinal cord is already being used to re-establish
locomotion in people paralyzed after
spinal cord injury.»
By combining cell physiology with pharmacology, behavioral analysis, and computer modeling, he has deciphered the existence of a central pattern generator for
locomotion in the
spinal cord, thereby linking circuit function to behavior.
The study is a breakthrough for our understanding of
spinal cord neuronal circuitry and its control of
locomotion in vertebrates.
Early on, he demonstrated that networks within the mammalian
spinal cord can produce the detailed motor pattern of
locomotion involving the coordination of hundreds of different muscles.