Sentences with phrase «spines in normal mice»
Light stimulation did not boost the number of spines in normal mice or strengthen the fear memory, nor did indiscriminately shining light in the dentate gyrus result in any long - term memory improvement.
https://www.sciencedaily.com/ Not exact matches
Remarkably, giving animals injections of lithium salts — which mimics WNT signaling by inhibiting the molecule GSK3 — or giving animals a more specific GSK inhibitor, the researchers were able to restore normal synapse and spine numbers and also improve some of the most significant psychiatric - like behavioral abnormalities in these mice.
«The J20 / caspase -2 null mice showed the same dendritic spine density and morphology as the normal mice — as opposed to the deficits in the J20 mice,» said co-lead author Julio Pozueta, PhD.
«The successful retrieval of memories in AD mice by increasing the number of spines for normal memory processing only in the memory cells, rather than in a broad population of cells, highlights the importance of highly - targeted manipulation of neurons and their circuits for future therapies.
«The successful retrieval of memories in AD mice by increasing the number of spines for normal memory processing only in the memory cells, rather than in a broad population of cells, highlights the importance of highly - targeted manipulation of neurons and their circuits for future therapies,» said Tonegawa in a statement.