Sentences with phrase «splicing dna»

They procreate with genetic experiments — splicing DNA from a dozen animals into a lab - created life - form they hope to harvest for pharmaceutical properties — and their masterpiece is a pirate side - project involving human DNA spliced into their zoological genetic cocktail.

Clive and Elsa (Adrien Brody and Sarah Polley) are a team of top - notch genetic engineers who focus on splicing the DNA of different animals to create hybrid creatures.

Clive (Adrien Brody) and Elsa (Sarah Polley) are scientists who are very successful at splicing DNA from different animals to create bizarre hybrids with unique proteins that might be harvested for use in creating disease - fighting drugs.

More work is therefore needed to find this mechanism, which may open up new avenues for malaria treatments, for example by interfering with whatever is cutting and splicing the DNA in the parasite.

When Blakely's team spliced the DNA sequence that encodes the relevant fly amino acid into the mouse serotonin transporter gene, the mice now made a transporter that was 80 times less sensitive to cocaine, while allowing the transporter to function completely normally.

The resulting parts are pieces of DNA with specific ends that act as targets for enzymes that cut and splice DNA.

That gathering on the Monterey Peninsula was called after scientists realized they could splice DNA from one organism into another.

Since we spent the day talking about the publishing revolution, maybe we should splice some DNA and catch up!

Upgrade your virus, splice DNA, and unlock dozens of undead creatures with unique powers.

Not exact matches

By manipulating DNA and splicing in genes from other animals, adding a la carte features that would make an ordinary T - Rex even more crowd - pleasing.

(Ligases are enzymes that splice together other molecules such as DNA or RNA.)

For most genes, after RNA is read out from the DNA (transcription), some of the RNA must be spliced out.

Florigene researchers had to splice a gene that produces the blue pigment delphinidin into rose DNA and also turn off the rose's natural red pigment gene.

They found that several proteins and DNA sequences play an important role, most notably the integrase enzymes that actually splice the Ty3 retrotransposon into a chromosome (Science, vol 267, p 1488).

In bacteria, the system takes bits of DNA from viruses and splices them into the cell's own DNA so that they can be recognised and attacked in future.

That viral DNA is then directly spliced into the host cell's DNA and passed along with the cell's natural replication process.

To better understand how the process works, they focused on the large mobile DNAs, such as plasmids, which exist as free DNA circles apart from the bacterial chromosome, and genomic islands, which can splice themselves into the chromosome.

He sifted through thousands of snapdragon plants to find transposons — short DNA sequences that can splice copies of themselves...

Van Montagu first isolated the DNA responsible for producing the bug - killer protein, then spliced it into the genome of A. tumefaciens.

Not only could their new construction, dubbed «Sleeping Beauty,» slip into chromosomes, but a small test gene spliced into the transposon was also imported into the DNA of fish and human cells.

The new study demonstrates how a wide range of mutations can be corrected in human cells by eliminating abnormal splice sites in the genomic DNA.

The cell splices out the introns and joins up only those DNA sequences that code for the protein.

Dominski and Kole designed antisense oligonucleotides that bind to and «neutralise» the DNA sequences that trigger incorrect splicing.

To produce a globin protein molecule, the DNA of the globin gene is first transcribed into a long RNA molecule from which internal segments must be excised, or spliced out, to generate the RNA template for protein synthesis in the red cell.

But when retroviruses like HIV infect a cell, they often let the cell live and splice their genes into its DNA.

And studies have shown that DNA packed in a doughnut - shaped torus is easier to repair, because the torus holds the broken strands in place until they can be spliced back together.

The researchers learned that the astonishing diversity of cadherin in pink bollworm from India is caused by alternative splicing, a novel mechanism of resistance that allows a single DNA sequence to code for many variants of a protein.

To make potato plants produce the enzyme, the researchers «spliced» the appropriate genes from E. coli into their DNA.

While the practice of splicing foreign DNA into food crops has become common in corn and soy, few companies or researchers have dared to apply genetic engineering to plants that provide an essential strut of the U.S. economy, trees.

Black made copies of these genes and spliced the material into tiny loops of DNA called plasmids.

Information stored in the DNA of genes is transcribed into immature «pre-messenger RNAs» (pre-mRNAs), pre-mRNAs are then spliced into mature «messenger RNAs» (mRNAs), and finally, mRNAs are translated into proteins.

Proteins are synthesized from instructions coded in the DNA through a multi-step process that includes RNA splicing.

The RNA processing factors THRAP3 and BCLAF1 promote the DNA damage response through selective mRNA splicing and nuclear export.

SPLICE is a theatrical depiction of rebellious scientists manipulating DNA.

Filed Under: Sequencing Technology, Uncategorized Tagged With: assembly, deletions, DNA, genetics, genome, genomics, illumina, indels, informatics, sequencing, snps, splicing

The therapy is an 18 - letter string of DNA that corrects aberrant splicing by binding a unique sequence on SMN2 «s messenger RNA located just downstream of the crucial seventh exon, thereby obstructing components of the RNA splicing machinery (see «Bring to one's antisenses»).

psq is a widely expressed gene that by alternative splicing gives rise to several protein variants that share a PSQ DNA - binding motif (Weber et al. 1995; Horowitz and Berg 1996; Lehmann et al. 1998).

Filed Under: NGS Informatics, Uncategorized Tagged With: alignment, cancer, deletions, DNA, genome, genomics, illumina, indels, insertions, maq, selection, sequencing, snps, splicing, TCGA, translocations

Filed Under: Cancer Genomics, Uncategorized Tagged With: cancer, DNA, genetics, genome, genomics, noncoding, research, selection, sequencing, snps, splicing, TCGA

We describe the first Niam embryonic stem cell interactome, which includes proteins with roles in DNA replication and repair, transcription, splicing and ribosome biogenesis.

So in the process of copying the DNA into RNA, first a copy is made of the entire gene, and then the non-coding regions are removed from RNA, in a process called splicing.

Site - directed mutagenesis in a biologically active nucleic acid for the purpose of reverse genetics of phage Qß; method extended to DNA to determine structure - function relationships in the promoter and splice sites of the ß - globin gene.

Yang — whose essay described examples of alternative splicing, a process by which the same stretch of DNA and its complementary messenger RNA can be spliced together in different ways and thus be translated into different proteins — will receive a $ 1000 prize.

To identify mutations in categories like these, we rely largely on computational tools that identify and score «motifs» — DNA sequences bound by micro-RNAs, splice enhancers, and other post-transcriptional players.

Laboratory assays evaluating the effect of DNA sequence variants on BRCA1 mRNA splicing may contribute to classification by providing molecular evidence.

Adapted here by Alex Garland, riding on the modest success of his directorial debut, Ex Machina, as an infidelity mystery wrapped in big science fiction ideas and a splicing of cinematic DNA of Andrei Tarkovsky and John Carpenter, among others.

The mutagen is explained away as a CRISPR - enabled instant DNA splice, but the story keeps changing, depending on the moment: it apparently also involves growth hormones, recombinant DNA that gives the mutated animals various superpowers, and some kind of programmed vulnerability to a homing beacon.

Clive and Elsa (Brody and Polley) are biochemists working for a monolithic pharmaceutical corporation, splicing together animal DNA to find proteins that can treat diseases.

They specialize in splicing together DNA from different animals to create fantastical new hybrids.

Imagine a crazy article you'd read in Wired spliced with the DNA of the original Terminator.