Sentences with phrase «spontaneous mouse model of breast cancer»
2) The two repeated experiments analyze the source of POSTN expression in the lung and whether it affects the number / size of primary and secondary tumor formation in a spontaneous mouse model of breast cancer (MMTV - PyMT).
https://elifesciences.org/
Deletion of the amino acid transporter Slc6a14 suppresses tumour growth in spontaneous mouse models of breast cancer
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Therefore, we have explored the role of the alpha2 beta1 integrin in cancer initiation and progression using a clinically - relevant, spontaneous mouse model, the MMTV - Neu model of breast cancer progression and metastasis.
In the present study, we interrogated the role of this transporter in breast cancer by deleting Slc6a14 in mice and monitoring the consequences of this deletion in models of spontaneous breast cancer (Polyoma middle T oncogene - transgenic mouse and mouse mammary tumour virus promoter - Neu - transgenic mouse).