Some antioxidants such as vitamin E and vitamin A are vital for preventing acne, by providing inbuilt defences to sebum which prevent it from mutating into a highly comedogenic form called
squalene peroxide.
Lipid peroxides are particularly deadly, as they 1) oxidise the sebum on your face, producing a potent pore - clogging compound
called squalene peroxide, and 2) deplete nutrients like vitamin E and A.
Infused
with squalene oil derived from the olive leaf to condition lips while providing a sheer pop of color in three new shades
If you were to boil down the birth of blackheads to two causes they would be 1) the oxidation of sebum, and 2) excessive keratin production, even prior to
when squalene peroxide triggers it.
Firstly, antioxidants are vital for clearing acne: they are an overlooked strategy for preventing clogged pores, because they prevent the production
of squalene peroxide on your skin's surface.
It really looks like the body uses vitamin E to protect
squalene in the skin.
It's particularly important for preventing
squalene from oxidation because it's your sebum's favoured defensive tool.
This then
forms squalene peroxide, which is one of the most comedogenic substances in the world; in other words, it's great at blocking your skin pores.
Getting enough antioxidants is vital for your skin because they are needed to
protect squalene from oxidising.
Made with only 35 % powder and infused with sugarcane - derived
squalene for a weightless longwear, this formula, combined with its autumnal hue, cemented the chic shade as a favorite on - sight.
In clear skinned people this system is working very effectively; vitamin E is preventing
squalene oxidation, pores aren't getting blocked, and there is no acne...
Another recent favorite is Indie Lee
Squalene Oil which is very affordable and I am a sucker for good branding.
Hi, I was wondering — does topical vitamin E help
prevent squalene oxidization or only sources from the diet?
It is so powerful that in one study scientists could create acne simply by
applying squalene peroxide to a rabbit's ear.
Using a combination of human cancer cells and mouse models of disease, the authors examined the pathway by
which squalene epoxidase promotes the development of hepatocellular carcinoma and identified terbinafine, a clinically approved antifungal drug, as a potential intervention.
By studying the mechanism of hepatocellular carcinoma arising in the setting of nonalcoholic fatty liver disease, Liu et al. discovered a role for
squalene epoxidase, a metabolic enzyme involved in cholesterol biosynthesis.
2nd Skin Foundation:
Olive Squalene + Fruit Figments An ideal base for achieving the coveted «no makeup» makeup look, 100 % Pure's 2nd Skin Foundation is a weightless serum foundation formulated with olive squalane and pure fruit pigments to deliver a brighter, more youthful appearance.
Vitamin E is the main antioxidant used to protect the skin, and prevents your skin's oil from oxidising and mutating into compounds
like squalene peroxide which trigger even more oil production.
Plant
derived Squalene actively rebuilds lipids in the skin which supports healthy collagen levels.
Phosphorylation of supernatant protein factor enhances wits ability to stimulate microsomal
squalene monooxygenase.
If you add plenty of antioxidants to your diet the
extra squalene from testosterone will be protected, and this scenario won't happen.
It is high in vitamins E, K, and A along with
squalene so it's very antioxidant rich.
Glutathione has been furiously researched over the last ten years, and numerous promising benefits for acne have emerged: 1) hoovering up skin - destabilising swarms of free radicals, 2) strengthening your skin against sunlight, 3) preventing the pore -
clogging squalene peroxide from being born, and 4) much more.
Our RNA sequencing analysis of NAFLD - HCC samples
revealed squalene epoxidase (SQLE) as the top outlier metabolic gene overexpressed in NAFLD - HCC patients.
Ordinarily, your body equips all
manufactured squalene with vitamin E defences to prevent this from happening.
What
makes squalene peroxide doubly effective is that it stimulates a local increase in sebum.
If anything, the
outside squalene will just add to your antioxidant requirements slightly.
The amount of
squalene produced basically outnumbers the amount of antioxidants available.
To summarise, sebum oxidation
creates squalene peroxide, which triggers a massive increase in the substances that block your pores.
I think this crucial information
about squalene oxydation is the last piece of the puzzle for me.
A high proportion of MUFA, as provided by olive oil (which contains
also squalene, a powerful antioxidant) or canola oil, with a good amount of omega - 3 (flax oil, walnut oil; the latter has much less omega - 3 however) sounds definitely more reasonable than a diet containing 75 % carbs or more.
The more antioxidants you have in your body, the
less squalene peroxide is formed on your skin, and the less pimples you develop.
Comprised of sweet almond oil, plant -
based squalene, licorice root, and lemon extract, it compliments skin by bringing out its natural glow.
Now, about this particular product, after reading about Indie Lee's journey and being in dire need of a new facial oil, I decided to
give Squalene Facial Oil a try and I am really impressed!
Factor in SPF 40 and powerhouse moisturizers (
including squalene and shea butter) and you'll see why it's actually worth its $ 100 price tag.
He also procured the rat sex -
pheromone Squalene from a rat lab and applied it to various surfaces of the gallery.
Buchanan's team has identified certain compounds, such
as squalene, common to the fingerprints of children as well as adults.
When squalene oxidises it kicks off a chain of events that allows your pores to get blocked, and that is the key requirement for acne to form.
When your antioxidant supplies are depleted, the oil on your face (sebum) is prone to damage, creating a by - product
called squalene peroxide that is among the most potent pore - clogging substances on planet earth.
I use argan and
squalene in a face cream I make and it's a great combo.
What's even more interesting is that the amount of acne produced correlated directly to the amount
of squalene peroxide applied.
Although
Olive squalene has a slightly more oilier feel about it than silicones, it absorbs totally into your skin dragging with it any essential oils that have been added.
When your sebum oxidises it
forms squalene peroxide, which is great at blocking your pores and is basically the king of all substances when it comes to doing so.
... but other antioxidants will help too; vitamin E has numerous other antioxidant functions in the body, and by getting other antioxidants you can relieve it from these duties and allow it to focus on
protecting squalene.