Sentences with word «squamous»
The word "squamous" refers to something that is flat, thin, and scale-like in shape or appearance. Full definition
Hydrochlorothiazide increased the risk of basal cell carcinoma, which is the least serious type of skin cancer, as well as of squamous cell carcinoma, which is more aggressive and in some cases manages to spread to other parts of the body.
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ANXA1 affects cell proliferation, invasion and epithelial - mesenchymal transition of oral squamous cell carcinoma.
The trial enrolled 361 patients with recurrent or metastatic head and neck squamous cell carcinoma who had not responded to platinum - based chemotherapy, a rapidly progressing form of the disease with an especially poor prognosis, said Dr. Ferris.
Kelly, 58, was diagnosed with squamous cell carcinoma isolated to his upper jaw in June 2013.
The prevalence of itch was greatest in squamous cell carcinoma (46.6 percent), followed by basal cell carcinoma (31.9 percent) and melanoma (14.8 percent).
[17] While use of alcohol and tobacco have been shown to increase one's risk of developing squamous cell carcinoma of the head and neck, no similar evidence exists for mucosal melanoma.
«We'd like to extend this further to examine for driver genes in other types of lung cancer, such as squamous cell lung cancer.»
Both drugs are approved for treating metastatic melanoma, and Opdivo is also approved for squamous lung cancer.
MicroRNA - 34a directly targets high - mobility group box 1 and inhibits the cancer cell proliferation, migration and invasion in cutaneous squamous cell carcinoma.
The ΔN isoforms of p63 may also serve as stem cell markers in a variety of epithelial cell types, including endometrium [30], cervix [31], breast [32], prostate [33], and in stratified squamous epithelium [21,34].
Patients with epidermal growth factor receptor (EGFR) expressing advanced squamous non-small-cell lung cancer benefit most from necitumumab added to gemcitabine and cisplatin chemotherapy, according to a subgroup analysis from the SQUIRE trial presented today at the European Lung Cancer Conference (ELCC) 2016 in Geneva, Switzerland.
The epidermis consists of scale like cells called squamous epithelium, basal cells and melanocytes.
The papillomavirus can cause warts around the mouth of your dog, and it's also suspected of causing squamous cell carcinomas.
Ultraviolet damage might be more extensive in Haflingers (and possibly other breeds) due to a genetic mutation that increases the risk for developing limbal squamous cell carcinoma (SCC).
In men, adenocarcinoma was the most common type (42 %), followed by squamous cell carcinoma (35 %), small cell lung cancer (18 %), and others (5 %).
The outermost layer of our skin is composed of dead squamous epithelial cells, as are the mucous membranes lining the inside of mouths and body cavities
The FDA approved two anti-PD-1 antibodies (nivolumab / Bristol - Myers Squibb and pembrolizumab / Merck & Co.) for metastatic melanoma in 2014, and it extended approval to metastatic squamous non-small cell lung cancer earlier this year.
Protein Kinase Casein Kinase 2 Mediates Inhibitor - κB Kinase and Aberrant Nuclear Factor - κB Activation by Serum Factor (s) in Head and Neck Squamous Carcinoma Cells
Type I mucosal surfaces line the upper rectum and consist of a single layer of tightly joined, simple columnar epithelium, while type II mucosal surfaces line the lower rectum and anus and consist of multiple layers of stratified squamous epithelium.
Research reveals that both in cell lines as well as mouse models, grape seed extract kills neck and head squamous cell carcinoma cells, though keeping healthy cells unharmed.
We focus on squamous tissues, the skin epidermis and the lining of the oesophagus, using transgenic models, novel sequencing approaches, live imaging and single cell analysis to uncover key steps in cancer development, with aim of developing rational interventions to decrease cancer risk.
2 years ago last week she passed away from squamous cell skin cancer.
Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): a phase 2, single - arm trial.
Senoo M, Tsuchiya I, Matsumura Y, Mori T, Saito Y, Kato H, Okamoto T, Habu S. Transcriptional dysregulation of the p73L / p63 / p51 / p40 / KET gene in human squamous cell carcinomas: expression of Delta Np73L, a novel dominant - negative isoform, and loss of expression of the potential tumour suppressor p51.
Other oral tumors include squamous cell carcinoma (malignant), and other benign tumors such as fibromas, lipomas, and histiocytomas.
With his players alongside, the 58 - year - old Karl revealed at a Feb. 16 press conference that he was embarking on a six - week course of radiation and chemotherapy to treat squamous cell neck - and - throat cancer.
Pembrolizumab is well - tolerated and shows promising antitumor activity and early survival rates among patients with PD - L1 — positive cervical squamous cell cancer, according to preliminary results of the KEYNOTE - 028 trial.
B, DDX3 nuclear staining in normal and neoplastic squamous tissues of skin.
I'm also collaborating with Matt Spector, who is a head and neck surgeon, to look at squamous cell carcinoma.
«Prognostic factors identified for peripheral squamous cell carcinomas of the lung.»
«This model supported cancer development so strongly that some mice developed invasive squamous cell skin cancers similar to the patient's tumor,» said lead author Shadmehr Demehri, MD, PhD, a dermatologist and postdoctoral fellow.
The patient's diagnosis with Marjolin's ulcer, an invasive and potentially deadly squamous cell cancer, surprised physicians.
Dalmatians are also susceptible to sunburn and thus to skin cancer (especially squamous cell carcinoma).
As shown in Fig. 6B, both the nuclear staining intensity of DDX3 and the percentage of cells positive in DDX3 nuclear staining were much higher in normal epidermis as compared with neoplastic squamous cells (normal versus SCC, 94 % versus 18 % cases for strong and moderate grade intensity; 94 % versus 12 % cases with > 50 % DDX3 nuclear staining positive cells; P < 0.001).
They found basal cell skin cancers cost $ 5,760 per person, while squamous cell carcinoma can exceed $ 10,500 (in Canadian currency).
«There's been a preponderance of HPV - related squamous cell carcinoma of the base portion of the tongue,» he says.
Radiocarbon, an international journal of radiocarbon and other isotope dating In a study of the mutational landscape of p53 - immunopositive patches (PIPs), which may represent early squamous cell carcinoma precursors in the skin
Tonsillar squamous cell carcinomas almost invariably metastasize to local lymph nodes and two - thirds show distant metastasis, often to the lungs, although they can spread to many different organs, including the bones.
Generally, all are darkhaired breeds, and a dark coat color has been associated with the development of subungual squamous cell carcinomas arising on multiple digits, often on different extremities.
Overview Squamous cell carcinoma (SCC) is the most common oral tumor in cats and typically affects middle - aged to older cats.
A common cancer in the breed is digital squamous cell carcinoma, which originates in the toes.
Other conditions such as syphilis, irritation, scarlet fever, vitamin deficiency (especially vitamin B complex), traumatic fibroma, and squamous papilloma have been associated with this problem.
Squamous metaplasia of the respiratory tract, conjunctiva, endometrium, and salivary glands has been noted.
So far, little was known about the molecular mechanisms connecting squamous cell carcinomas and RDEB.