Sentences with phrase «squamous carcinoma cells»

Dr. Islam's discovery was published [S. Islam, T. E. Carey, G. T. Wolf, M. J. Wheelock, and K. J. Johnson, «Expression of N - Cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell - cell adhesion,» J. Cell Biol.

Not exact matches

Kelly, 58, was diagnosed with squamous cell carcinoma isolated to his upper jaw in June 2013.

«The object of this study was to examine the sentinel lymph node alone in women with squamous cell carcinoma of the vulva and evaluate their recurrence in the groin and any complication rates,» Dr. Moore explains.

The researchers focused on three types of skin cancer: cutaneous melanoma, basal cell carcinoma and squamous cell carcinoma.

The trial enrolled 361 patients with recurrent or metastatic head and neck squamous cell carcinoma who had not responded to platinum - based chemotherapy, a rapidly progressing form of the disease with an especially poor prognosis, said Dr. Ferris.

Now a team of researchers has been able to identify accurately the sentinel node (SN) in head and neck squamous cell carcinoma (HNSCC) using a novel tracer; a challenging task because there are up to 150 different lymph nodes in the neck, and the differentiation of true SNs from secondary nodes is difficult.

The majority of the patients» lesions (53 percent) had squamous cell carcinoma, and the remaining 47 percent had adenocarcinoma.

Non-melanoma skin cancers — specifically, basal cell carcinoma and squamous cell carcinoma — are more likely than melanoma to involve itch or pain, the study found.

The prevalence of itch was greatest in squamous cell carcinoma (46.6 percent), followed by basal cell carcinoma (31.9 percent) and melanoma (14.8 percent).

In the case of head and neck squamous cell carcinoma, for example, high stemness indices correlated with mutations in the gene NSD1.

A dearth of skin pigment leaves people more susceptible to nonmelanoma skin cancers such as squamous cell carcinoma and basal cell carcinoma.

«Prognostic factors identified for peripheral squamous cell carcinomas of the lung.»

Lung cancer is the most common cause of cancer - related death worldwide and lung squamous cell carcinomas (SCC) account for 20 - 30 % of all NSCLC.

Fragile skin that blisters easily: 90 percent of the patients that suffer from the skin condition recessive dystrophic epidermolysis bullosa (RDEB) develop rapidly progressing cutaneous squamous cell carcinomas, a type of skin cancer, by the age of 55.

So far, little was known about the molecular mechanisms connecting squamous cell carcinomas and RDEB.

Indeed, when Blanpain and his colleagues examined mice with squamous cell carcinoma, a malignant outgrowth of the papilloma, they found that most of the cells were actively dividing, not just a small subset of stem - cell - like cells.

The Ogretmen laboratory screened previously reported microarray data sets of several human tumor tissues (metastatic head and neck squamous cell carcinoma, melanoma, and renal cell carcinoma) and showed that, in these samples, only the levels of CerS4 were significantly decreased.

New results from a clinical trial involving more than 900 military veterans at high risk for keratinocyte carcinoma skin cancer provides evidence that using the generic skin cream fluorouacil 5 percent for two to four weeks may reduce the risk of a squamous cell carcinoma (SCC) needing surgery by 75 percent within a year.

However, a type of cellular signaling caused by the BRAF inhibitors may leave patients susceptible to secondary malignancies, such as squamous cell carcinoma and RAS - mutant leukemia.

Currently, her main area of practice is skin cancer, including basal cell carcinoma and squamous cell carcinoma.

Basal and squamous cell carcinoma are the most common types of cancer in the United States and represent the vast majority of all cases of skin cancer; however, they rarely result in death or substantial morbidity, whereas melanoma skin cancer has notably higher mortality rates.

In the past decade, medical research has discovered direct links between tanning bed use and higher rates of the skin cancers basal cell carcinoma, squamous cell carcinoma and melanoma.

The risk of skin cancer increases the more hydrochlorothiazide you have taken throughout your lifetime, and the risk of squamous cell carcinoma was up to seven times greater for people who had taken hydrochlorothiazide in an amount corresponding to > 10 years» use.

In the past decade, medical research has discovered direct links between tanning bed use and higher rates of the skin cancers basal cell carcinoma, squamous cell carcinoma and melanoma, according to Dr. Thomas.

Hydrochlorothiazide increased the risk of basal cell carcinoma, which is the least serious type of skin cancer, as well as of squamous cell carcinoma, which is more aggressive and in some cases manages to spread to other parts of the body.

More specifically, this refers to drugs containing hydrochlorothiazide and squamous cell carcinoma.

Researchers examined 1,021 slides of specimens, which had a total of 136 basal cell carcinomas, 94 squamous cell carcinomas and 15 melanomas.

There are other types of skin cancers that are less concerning, mainly squamous cell carcinoma and basal cell carcinoma, which tend to be (thankfully) much more common than melanoma.

The current standard of care for advanced head and neck squamous cell carcinoma involves chemotherapy and radiation.

Spindle cell carcinoma is an aggressive variant of squamous cell carcinoma.

Researchers have found that people with advanced head and neck squamous cell carcinoma and the KRAS - variant inherited genetic mutation have significantly improved survival when given a short course of the drug cetuximab in combination with standard chemotherapy and radiation.

They discovered that people with both head and neck squamous cell carcinoma and the KRAS - variant who were treated with standard treatment, but not with cetuximab, had a higher risk of failing treatment and developing metastatic disease, meaning the cancer spreads to distant organs and is incurable.

NRG Oncology researchers recently developed and validated a nomogram that can predict 2 - year and 5 - year overall survival (OS) and progression - free survival (PFS) for patients with local - regionally advanced oropharyngeal squamous cell carcinoma (OPSCC) treated primarily with radiation - based therapy.

In the new research, Prins and Liau used a technique called adoptive cell transfer, which involves extracting and growing immune cells outside of the body, then reprogramming them with a gene known as New York Esophageal Squamous Cell Carcinoma, or NY - ESO cell transfer, which involves extracting and growing immune cells outside of the body, then reprogramming them with a gene known as New York Esophageal Squamous Cell Carcinoma, or NY - ESO Cell Carcinoma, or NY - ESO - 1.

It's also known to play a role in a form of leukemia, as well as liver cancer, squamous cell skin carcinomas, squamous cell cancers of the head and neck and other cancers.

So the group set out to test whether selenium might reduce the chance of recurrence of basal cell or squamous cell carcinoma in people previously treated for skin cancer.

Interestingly, genomic analyses suggested that ESCC and head and neck squamous cell carcinoma (HNSCC) shared some common pathogenic mechanisms, and ESCC development is associated with alcohol drinking.These findings would provide a brand - new insight into the understandings of ESCC tumorigenesis, and would help clinicians to develop more effective diagnostic and therapeutic approaches for ESCC.

Immunologic and metabolic characteristics of HPV - negative and HPV - positive head and neck squamous cell carcinomas are strikingly different.

(2017) Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas.

Changes in cell junctions induced by inhibition of epidermal growth factor receptor in oral squamous cell carcinoma cells.

14255: STAT3 Signaling During Chemo - Radiation for Squamous Cell Carcinoma of the Head and Neck 14340: A Phase II, Randomized, Open - Label, Multi-Center, Global Study of MEDI4736 Monotherapy, Tremelimumab Monotherapy, and MEDI4736 in Combination with Tremelimumab in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck (SCCHN) 14258: Randomized Phase II and Phase III Studies of Individualized Treatment for Nasopharyngeal Carcinoma Based on Biomarker Epstein Barr Virus (EBV) Deoxyribonucleic Acid (DNA)

The FDA granted approval to nivolumab (Opdivo), an anti-PD-1 checkpoint inhibitor, for patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) that has progressed despite platinum - based chemotherapy.

FOXM1 Induces a Global Methylation Signature That Mimics the Cancer Epigenome in Head and Neck Squamous Cell Carcinoma.

Adenocarcinoma of the Appendix, Anal cancer, Breast Cancer, Cancer, Squamous cell carcinoma, Colorectal Cancer, Esophageal Cancer, Esthesioneuroblastoma, Hodgkin lymphoma, Intrahepatic cholangiocarcinoma, Laryngeal cancer, Lip and oral cavity cancer, Liposarcoma, Liver cancer, Multiple myeloma, Nasopharyngeal carcinoma, Non-small cell lung cancer, Oral cancer, Osteosarcoma, Pancreatic cancer, Rectal Cancer, Salivary Gland Cancer, Stomach cancer, Synovial sarcoma, Testicular cancer, Tongue cancer, Vaginal cancer, Bladder cancer, Cervical cancer, Prostate cancer, Non-Hodgkin lymphoma, Brain Cancer, Thyroid Cancer, Ewing Sarcoma, Extrahepatic bile duct cancer, Melanoma

(HealthDay)-- Most active smokers with head and neck squamous cell carcinoma (HNSCC) have made one or more quit attempts, according to a study published online April 12 in JAMA Otolaryngology - Head & Neck Surgery.

To date, the TCGA Research Network has generated data and published analyses on glioblastoma multiforme, ovarian serous adenocarcinoma, colorectal adenocarcinoma, lung squamous cell carcinoma and invasive breast cancer.

MicroRNA - 34a directly targets high - mobility group box 1 and inhibits the cancer cell proliferation, migration and invasion in cutaneous squamous cell carcinoma.

Identification of a human papillomavirus - associated oncogenic miRNA panel in human oropharyngeal squamous cell carcinoma validated by bioinformatics analysis of the Cancer Genome Atlas.

The FDA granted accelerated approval to pembrolizumab (Keytruda), an anti-PD-1 checkpoint inhibitor, for patients with recurrent or metastatc head and neck squamous cell carcinoma (HNSCC).

Neuropilin 1 Receptor Is Up - Regulated in Dysplastic Epithelium and Oral Squamous Cell Carcinoma.