Sentences with phrase «stable expression of»

Dr. Hughes also reported ongoing work to achieve stable expression of a biocatalyst in yeast, which enables the fungi to produce biodiesel after ethanol production has completed.

However, these studies are limited by the requirement for stable expression of an exogenous gene.

It's not that methylation doesn't do anything at all — in fact, the researchers found that it is primarily associated with genes that serve crucial functions for workers and queens alike, suggesting that DNA methylation might contribute to the stable expression of so - called household genes.

Not exact matches

«A religious body,» he says, «is a stable institution with a heritage which it cherishes, a government which gives organized expression to its faith, and a body of members whose duties and values are generally recognized.»

As CaMKII expression has been associated with consolidation and permanence of memories in other brain regions, this switch may reflect the formation of a stronger and more stable opiate reward memory.

Because plate motions are merely the surface expression of the underlying dynamics of the Earth's mantle, Conrad and his colleagues were able to infer that upwelling flow in the mantle must also remain stable over geologic time.

Tapio, meanwhile, has adapted standard proteomics techniques so that they can be applied to some of the old tissues, and several groups are studying whether micro-RNAs — which help to control gene expression and are relatively stable — are present in the samples.

We notably follow the time course of structural changes in response to cues that affect gene expression either transiently or permanently: changes in genome structure during transient hormonal response of differentiated cells and stable trans - differentiation of B cells to macrophages.

His group is are studying the mechanism of stable inherited epigenetic transcriptional repression by Polycomb - group (Pc - G) protein complexes, and the effects of deregulation of Pc - G genes on Homeobox gene expression, development, Cell cycle control and cancer formation.

In work published in the summer of 2016 in the journal Developmental Biology, researchers looked at 17 different development stages of axolotl embryos and found a highly unusual series of bursts in changes in gene expression, followed by stable periods, that is unique in developmental biology.

14: Boominathan A, Vanhoozer S, Basisty N, Powers K, Crampton AL, Wang X, Friedricks N, Schilling B, Brand MD, O'Connor MS. Stable nuclear expression of ATP8 and ATP6 genes rescues a mtDNA Complex V null mutant.

Previous work has given insights into the mechanistic pathways leading to small molecule sequestration in membrane - free coacervate protocells; successfully demonstrated the use of liquid - liquid phase separated micro compartments for protein expression using cell free expression systems; exploited microfluidics for the high throughput formation of stable, monodisperse microdroplets; and integrated two contrasting modes of protocell construction to produce a novel hybrid model based on fatty acid membrane - bound coacervate micro-droplets.

In addition, the Liver - Chip maintained stable physiologic levels of key hepatic functions, such as albumin secretion, urea secretion, and expression of CYP450s drug metabolizing enzymes.

An AAV gene therapy approach has shown in preclinical in vivo models to produce stable gene expression, enhanced survival, and prevention of hypoglycemia.

Indeed this sort of model has been used to explain the existence of a stable attractor and associated lineage primed states in EML cells, a haematopoietic progenitor cell line [54], and as the basis for heterogeneity in Nanog expression in ES cells [11].

To further investigate the role of STAT6 in regulating constitutive COX - 2 expression, a deleted form of STAT6 lacking the C - terminal 186 amino acids (aa)(from 662 - 847, MW 75 kDa) that has been shown to act dominant - negatively (STAT6 DN) was constructed and stable cell lines were established (Mikita et al., 1996).

Dr. Mikhail Liskovykh an expert in Human Artificial Chromosomes (HAC) construction and transfer, including the assembly of centromere arrays, generating conditionally stable HACs, and cloning complete genetic loci for expression in human cells.

The IME Molecular Biology Division has a long standing expertise in the expression of recombinant proteins like therapeutic antibodies and vaccines using different transient and stable plant - based systems.

Depending on the user projects future perspectives, the expression screening will include plant suspension cells and / or initiation of stable plant generation with respect to future manufacturing processes.

However, like most vertebrate cell lines, target sequences are inserted randomly and stable mutation and expression of the transcript can not be controlled for.

In addition to effects on translation and DNA replication gene expression, high - replicate RNA - seq in morphologically normal individuals demonstrates a stable regulatory response of epigenetic modifiers and the specific de-repression of a group of zinc finger genes residing in constitutive heterochromatin.

If, as Ellis writes, «The dominant intellectual legacy of the Revolution, enshrined in the Declaration of Independence, stigmatized all concentrated political power and even... depicted any energetic expression of governmental authority as an alien force that all responsible citizens ought to repudiate and, if possible, overthrow» [p. 11], what compromises were made in order to bring a stable national government to fruition?

Tillmans is constantly evolving ahead of the political mainstream and with its current shift to the right, hopefully, by getting the message out there through exposure we will secure a more stable world, where art and free expression thrives.

Since to me (and many scientists, although some wanted a lot more corroborative evidence, which they've also gotten) it makes absolutely no sense to presume that the earth would just go about its merry way and keep the climate nice and relatively stable for us (though this rare actual climate scientist pseudo skeptic seems to think it would, based upon some non scientific belief — see second half of this piece), when the earth changes climate easily as it is, climate is ultimately an expression of energy, it is stabilized (right now) by the oceans and ice sheets, and increasing the number of long term thermal radiation / heat energy absorbing and re radiating molecules to levels not seen on earth in several million years would add an enormous influx of energy to the lower atmosphere earth system, which would mildly warm the air and increasingly transfer energy to the earth over time, which in turn would start to alter those stabilizing systems (and which, with increasing ocean energy retention and accelerating polar ice sheet melting at both ends of the globe, is exactly what we've been seeing) and start to reinforce the same process until a new stases would be reached well after the atmospheric levels of ghg has stabilized.

73 Moreover, as regards those resources, the expression «recourse to the social assistance system» in Article 7 (1)(c) of Directive 2003/86 does not allow a Member State to refuse family reunification to a sponsor who proves that he has stable and regular resources which are sufficient to maintain himself and the members of his family, but who, given the level of his resources, will nevertheless be entitled to claim special assistance in order to meet exceptional, individually determined, essential living costs or income support measures (see Chakroun, paragraph 52).