Not exact matches
(n = 30), controls (n = 30),
mild cognitive impairment (MCI) converting to AD (n = 34), and
stable MCI (n = 40).
Herein we analyzed the level of 24OH - C esters (% 24OH - CE) in i) cerebrospinal fluid (CSF) and homologous serum of AD (n = 13) and controls (n = 8); ii) plasma from AD... (n = 30), controls (n = 30),
mild cognitive impairment (MCI) converting to AD (n = 34), and
stable MCI (n = 40).
Participants were divided into four groups: those diagnosed with probable Alzheimer's when entering the study, healthy controls with no sign of dementia, individuals with
mild cognitive impairment that remained
stable over the two to three years for which scans were available, and those with
mild cognitive impairment that progressed to Alzheimer's disease during the study.
At the start of the study, blood caffeine levels were 51 % lower in participants identified as having
mild cognitive impairment who progressed to Alzheimer's over the 2 to 4 year follow up compared to those whose
mild cognitive impairment stayed
stable throughout the same period.