Not exact matches
This early
stage research will explore how the virus targets
stem cells and provide the starting point to develop new treatments that seek out the tumour and spare the surrounding healthy
brain tissue.
In a study being published in the journal Neuron, researchers show that the signal molecule TGF - beta acts as a time signal that regulates the nerve
stem cells» potential at different
stages of the
brain's development — knowledge that may be significant for future pharmaceutical development.
One type of
stem cell can produce multiple types of nerve
cells at different
stages of the
brain's development.
During the initial
stages of typical
brain development,
stem cells go through a period in which they divide to make more
stem cells, increasing their numbers.
Retrotransposons are normally silenced to prevent harmful mutations from occurring in egg and sperm
cells, but are mobilized during certain
stages of
brain development, when neurons are being produced from dividing
stem cells.
In this method, skin
cells are turned directly into
brain, heart, liver, or pancreas
cells without going through a
stem cell stage first.
Supported by a CIRM translational grant, scientists in Huang's laboratory are using human
stem cells to create inhibitory neuron progenitors — early -
stage brain cells that can develop into mature inhibitory neurons.