Not exact matches
Merck is the latest company to weather bad news in the Alzheimer's drug race, halting a late -
stage trial yesterday in an experimental amyloid - targeting candidate called verubecestat after a
data monitoring committee said there was «virtually no chance of finding a positive clinical effect,» Reuters reported.
According to PhRMA, there are more than a dozen experimental treatments that are still in phase 3, the latest
stage of clinical
trials before companies present their
data to the FDA.
Although Anavex Life Sciences» Alzheimer's disease program should offer up plenty of
data to digest this year, its research program is very early
stage, and the company's balance sheet is worrisome enough for me to avoid it until placebo - controlled
trial results are available.
Several years ago, for example, poor chemical probe
data led researchers to pursue a final
stage clinical
trial on a cancer drug candidate called iniparib.
Partnering with the U.S. Food and Drug Administration allowed Doebele and colleagues to access clinical
trial data describing initial tumor response, PFS and OS for 305 patients with
stage IIIb or IV non-small cell lung cancer on
trials of ALK inhibitors and 355 similar patients on
trials of immunotherapies directed at PD - 1.
Perhaslis says the goal is to integrate
data from lab - dish experiments all the way through end -
stage clinical
trials.
Innovative clinical
trial approaches that have proven successful in other disease areas such as oncology (e.g., platform
trials, umbrella and basket designs) might be employed with stratification of subjects by AT (N) profile, enabling a
data - driven approach to identify the biological
stage of disease in which an intervention has maximal treatment effects.
The researchers studied
data from 4,288 patients with
stage II or
stage III colon cancer who enrolled in either of two multi-center clinical
trials between July 1989 and February 1994.
OXGN is getting closer to present clinical
data from it's late
stage phase II and phase II / III
trials.
For example, if your legal assistant typically assists in the
data - and - document - gathering
stage of matters, let the client know that she will be hearing from the assistant; or if you handle family law agreements but refer away cases headed for
trial, make sure the client knows this;
With decades of experience in all
stages of the corporate
data lifecycle, from pre-matter consulting through legal hold,
trial and ultimate disposition of
data, Omnivere is uniquely positioned to minimize corporate risk while delivering unparalleled efficiency before, during and after legal, regulatory and compliance proceedings.
Following the publication of the
trial results last month, Livingston explained to CoinDesk why the lessons learned from that
data will finally set the
stage for the successful integration of social media with cryptocurrency.
Clinical Research Associates can work on various
stages of a clinical
trial, performing tasks such as creating
trial protocols, developing
trial methodology, collaborating with ethics committees, liaising with doctors running the
trial, making visits to the
trial site, ordering supplies, monitoring expenses, and authenticating
data collection forms.