Sentences with phrase «stage trial in»

The Chicago team has already formed a company, called Coordination Pharmaceuticals, which has raised seed funds to launch an early stage trial in humans, likely sometime in the second half of this year.

Specifically, Geron and J&J are expected to announce a go / no - go decision regarding the drug's late - stage trial in MDS anytime now.

The FDA actually approached Mitsubishi Tanabe and asked the firm to submit the drug for approval after it showed promise in a late - stage trial in Japan.

On average about 99 % of all drugs in clinical trials never actually make it to approval, and drugs are still failing late - stage trials in 2017.

The first product to market, Exubera by Pfizer, was withdrawn in 2007 because of this and several other companies shutdown their late - stage trials in response.

Juvista is moving into final stage trials in the middle of next year and the drug could be launched by 2011.

Not exact matches

While the new mid-stage study results from DNDi were impressive (they showed cure rates of 96 % to 97 % even for the sickest patients and those with liver scarring), more late - stage trials will be necessary before the drug is available on a large scale in the developing world.

Eleven, based in Cambridge, Mass., is going to continue developing Viventia's two main cancer drugs, one of which is in Stage 3 clinical trials.

But he stopped short of declaring the song in the public domain, leaving open the possibility that others may hold the copyright and setting the stage for a trial.

Solanezumab's inability to best placebo in a late - stage trial, combined with impending patent expirations for big sellers like the erectile dysfunction drug Cialis and ADHD medication Strattera, are largely driving the cuts.

The combo proved non-inferior to competing HIV medicines in a slew of late - stage clinical trials, and Gilead is expected to file a new drug application with the FDA soon.

In the opening - stage time trial, Phinney finished just outside the top 10 on the rain - slicked roads in Düsseldorf, in 12th place right among the world's fastest cyclistIn the opening - stage time trial, Phinney finished just outside the top 10 on the rain - slicked roads in Düsseldorf, in 12th place right among the world's fastest cyclistin Düsseldorf, in 12th place right among the world's fastest cyclistin 12th place right among the world's fastest cyclists.

To date, no gene therapies have yet been approved in the US, though one to treat another form of LCA has had promising results in late - stage trials.

Chief Executive Tom Blomfield recently told CNBCthat the company is in the early stages of talks to expand to the U.S. Revolut recently launched a trial in America.

Merck is the latest company to weather bad news in the Alzheimer's drug race, halting a late - stage trial yesterday in an experimental amyloid - targeting candidate called verubecestat after a data monitoring committee said there was «virtually no chance of finding a positive clinical effect,» Reuters reported.

The latest failure came in September, when Axovant said it failed a key late - stage trial for its drug, intepirdine.

In February alone, Lundbeck discontinued two of its trials, Merck discontinued one of its studies, and Accera failed a late - stage trial as well.

Still, more drugs are in late - stage trials that could have an impact on the disease, and researchers are pinning hopes on diagnosing the disease early, before symptoms even show up.

Intarcia has completed several late - stage clinical trials in which it uses the pump to deliver a glucose - controlling drug continuously for months — an idea, that if successful (and approved by the FDA) could significantly help patients with type 2 diabetes, fewer than half of whom maintain the recommended glycemic levels.

But a late - stage clinical trial called CheckMate - 026 for the drug failed to meet its primary goal of halting cancer progression in advanced, untreated patients whose tumors consisted of at least 5 % PD - L1.

According to PhRMA, there are more than a dozen experimental treatments that are still in phase 3, the latest stage of clinical trials before companies present their data to the FDA.

The biotech plans to shed 20 % of its nearly 600 employees in order to secure yearly cost - savings of about $ 21 million — money which can then be used to double down on late - stage clinical trials for its experimental Parkinson's drug.

In a late - stage study, Aimmune, a biotech immunotherapy allergy treatment taken via pill, found that of the roughly 500 kids with peanut allergies between the ages of 4 - 17 who were part of the trial, 67 % of those who received the treatment were able to tolerate 600 milligrams of peanut protein (about two to four peanuts) after about a year of treatment, while only 4 % of those who got the placebo could tolerate that dose of peanut protein.

The new Alzheimer's framework may not be much of a surprise given numerous, high - profile, late - stage clinical trial failures in the field by companies like Eli Lilly and Merck, and the decision by other companies (such as Pfizer) to back away from the risk - prone field.

Apps that are for demo, trial or test purposes or are in the beta stage do not get accepted by Apple.

Solanezumab, a drug developed by Eli Lilly that also acts on the amyloid hypothesis, failed some key clinical trials, though the company is still testing it in the pre-clinical stages of the disease.

Unfortunately for the firm, this enrollment halt may also implicate a future failure in a later - stage trial of the drug, PEGPH20.

And while early results have been promising, some skeptics have held out on the hype due to concerns over side effects and whether results will persist in later - stage trials.

In a late - stage trial, Darzalex combined with Velcade and chemotherapy slashed patients» risk of worsening disease or death by a stunning 61 % compared with the results for Velcade and chemotherapy alone.

The first stage of trials will be carried out on test tracks, and will try and iron out details like how close the trucks should be and what roads will be suitable, the Department for Transport said in a press release.

The Simpson trial set the stage for the Casey Anthony trial, the Oscar Pistorius trial, and any other recent case that played out in public (and on television) almost as much as it played out in the courtroom.

In May, Kite disclosed that one person had died in a clinical trial for its late - stage CAR - T therapy from cerebral edema, a condition in which excessive fluid causes the brain to swelIn May, Kite disclosed that one person had died in a clinical trial for its late - stage CAR - T therapy from cerebral edema, a condition in which excessive fluid causes the brain to swelin a clinical trial for its late - stage CAR - T therapy from cerebral edema, a condition in which excessive fluid causes the brain to swelin which excessive fluid causes the brain to swell.

Long before the Hogan trial took center stage, Gawker Media invested millions (Denton won't say how much exactly) in building a commenting and reader - blogging system it called Kinja, which Denton described as nothing less than an attempt to turn the publishing world on its head — to put readers on the same level with journalists and publishers.

BioNTech hit the headlines in July when its experimental personalized cancer vaccine, tailored to the tumors of individual patients, kept disease in check in an early - stage clinical trial.

These companies tend to have more dependable streams of revenue and a more diversified «pipeline» of drugs in the research and development stages, making them less dependent on make - or - break drug trials and their shares less volatile.

The fund is offered by BioShares alongside launched a sister fund, BBC, which targets biotech firms in the clinical trial stage.

But topping the list is Vertex (VRTX), which has a veritable plethora of HCV drugs in late - stage clinical trials, which are used either alone, or in combination with other drugs.

Generally speaking, you should only include those drugs that are already in one of the three clinical trial stages.

Then, once they're ready, they convert on a more middle - of - the - funnel offer like a product demonstration, a consultation, or a free trial, thus getting removed from the top - of - the - funnel nurturing campaign and swapped into the middle - of - the funnel campaign to get nurtured by content / offers more appropriate to that stage in the buying cycle.

Revenue from selling Celgene's therapies will fund the company's late - stage pipeline, which boasts three new cancer therapy candidates in pivotal trials.

Most biotechs would have shuttered a clinical program that showed absolutely no efficacy whatsoever in a late - stage trial, but Novavax has instead doubled down on RSV by going forth with its phase 3 trial of the RSV F vaccine for infants via maternal immunization, and begun planning for another trial in older adults that's reportedly on track to kick off in 2018.

The attentive reader can not fail to be struck with the amount of space allotted in them all to the closing stages of the story: the arrest, trial, and execution of Jesus, and the events immediately preceding and following.

Mechanization of red chile harvesting equipment is in the trial stage: less than 0.1 percent is harvested in this manner.

The only stage in doubt will be Saturday's time trial, but Froome is excellent in those anyway, so it will be tough to unseat him.

After the yellow - jersey wearer won the Stage 19 time trial, he's nearly sealed the overall Tour victory, which would make him the first British winner in the Tour's history.

LeMond first donned the yellow jersey after a time - trial victory in the fifth stage on July 6.

Developed by a Boston - based company, SmartSports, the SmartKage has been in a trial stage over the past year «'' which led to its installation at the Concord baseball school, one of just 100 test sites chosen across the country.

If, for example, the initial exercise work rate is excessively high, it will produce physiological changes that result in the conscious RPE being greater than that which the central controller considers optimal for a particular stage during an exercise trial.

There was no statistically significant difference in the frequency of postpartum hemorrhage among women undergoing immersion during the second stage of labor (RR, 0.14; 95 % CI, 0.10 — 2.71; one trial).

The 2009 Cochrane systematic review found no increase in maternal infections (RR, 0.99; 95 % CI, 0.50 — 1.96; five trials) with immersion during the first stage of labor.