Sentences with phrase «stage trial of»

The company said a late - stage trial of its cancer drug Abraxane met its main goal of improving the patient's time of survival without worsening skin cancer, when compared to standard chemotherapy.

said they will discontinue a late - stage trial of their experimental lung cancer drug after an interim analysis showed it would not meet the main goal of improving overall survival.

Unfortunately for the firm, this enrollment halt may also implicate a future failure in a later - stage trial of the drug, PEGPH20.

On October 18, 2013 Ariad announced that it was ending late - stage trials of the drug because of the increased risk of blood clots.

Not exact matches

Both Eli Lilly and Merck ditched late - stage Alzheimer's drugs they'd spent tens or even hundreds of millions of dollars developing after late - stage clinical trial failures over the past 12 months.

While the new mid-stage study results from DNDi were impressive (they showed cure rates of 96 % to 97 % even for the sickest patients and those with liver scarring), more late - stage trials will be necessary before the drug is available on a large scale in the developing world.

Eleven, based in Cambridge, Mass., is going to continue developing Viventia's two main cancer drugs, one of which is in Stage 3 clinical trials.

But he stopped short of declaring the song in the public domain, leaving open the possibility that others may hold the copyright and setting the stage for a trial.

The combo proved non-inferior to competing HIV medicines in a slew of late - stage clinical trials, and Gilead is expected to file a new drug application with the FDA soon.

To date, no gene therapies have yet been approved in the US, though one to treat another form of LCA has had promising results in late - stage trials.

It's the result of fears faced and erased, trial and error and tireless practice, on and off stage.

Chief Executive Tom Blomfield recently told CNBCthat the company is in the early stages of talks to expand to the U.S. Revolut recently launched a trial in America.

Merck is the latest company to weather bad news in the Alzheimer's drug race, halting a late - stage trial yesterday in an experimental amyloid - targeting candidate called verubecestat after a data monitoring committee said there was «virtually no chance of finding a positive clinical effect,» Reuters reported.

In February alone, Lundbeck discontinued two of its trials, Merck discontinued one of its studies, and Accera failed a late - stage trial as well.

Intarcia has completed several late - stage clinical trials in which it uses the pump to deliver a glucose - controlling drug continuously for months — an idea, that if successful (and approved by the FDA) could significantly help patients with type 2 diabetes, fewer than half of whom maintain the recommended glycemic levels.

But a late - stage clinical trial called CheckMate - 026 for the drug failed to meet its primary goal of halting cancer progression in advanced, untreated patients whose tumors consisted of at least 5 % PD - L1.

According to PhRMA, there are more than a dozen experimental treatments that are still in phase 3, the latest stage of clinical trials before companies present their data to the FDA.

The biotech plans to shed 20 % of its nearly 600 employees in order to secure yearly cost - savings of about $ 21 million — money which can then be used to double down on late - stage clinical trials for its experimental Parkinson's drug.

In a late - stage study, Aimmune, a biotech immunotherapy allergy treatment taken via pill, found that of the roughly 500 kids with peanut allergies between the ages of 4 - 17 who were part of the trial, 67 % of those who received the treatment were able to tolerate 600 milligrams of peanut protein (about two to four peanuts) after about a year of treatment, while only 4 % of those who got the placebo could tolerate that dose of peanut protein.

The new Alzheimer's framework may not be much of a surprise given numerous, high - profile, late - stage clinical trial failures in the field by companies like Eli Lilly and Merck, and the decision by other companies (such as Pfizer) to back away from the risk - prone field.

If you're suffering from advanced stages of cancer the best news your oncologist can deliver, apart from saying you're winning the battle, is that you're eligible for a promising new drug trial.

On average about 99 % of all drugs in clinical trials never actually make it to approval, and drugs are still failing late - stage trials in 2017.

Solanezumab, a drug developed by Eli Lilly that also acts on the amyloid hypothesis, failed some key clinical trials, though the company is still testing it in the pre-clinical stages of the disease.

In a late - stage trial, Darzalex combined with Velcade and chemotherapy slashed patients» risk of worsening disease or death by a stunning 61 % compared with the results for Velcade and chemotherapy alone.

Cowen analyst Colby Synesael agrees that Comcast's initial wireless foray appears to be more of a trial at this stage.

The first stage of trials will be carried out on test tracks, and will try and iron out details like how close the trucks should be and what roads will be suitable, the Department for Transport said in a press release.

BioNTech hit the headlines in July when its experimental personalized cancer vaccine, tailored to the tumors of individual patients, kept disease in check in an early - stage clinical trial.

ZURICH (Reuters)- Roche's Tecentriq immuno - oncology drug failed a late - stage follow - up trial against advanced bladder cancer, the Swiss drugmaker said on Wednesday, raising questions about whether regulators could scale back their approval of the medicine.

These companies tend to have more dependable streams of revenue and a more diversified «pipeline» of drugs in the research and development stages, making them less dependent on make - or - break drug trials and their shares less volatile.

Social Capital kicked off a trial of Carroll's model last year with a referral program of sorts — the fund asked other venture capital firms to direct promising early - stage companies to apply through the system.

But topping the list is Vertex (VRTX), which has a veritable plethora of HCV drugs in late - stage clinical trials, which are used either alone, or in combination with other drugs.

Generally speaking, you should only include those drugs that are already in one of the three clinical trial stages.

Then, once they're ready, they convert on a more middle - of - the - funnel offer like a product demonstration, a consultation, or a free trial, thus getting removed from the top - of - the - funnel nurturing campaign and swapped into the middle - of - the funnel campaign to get nurtured by content / offers more appropriate to that stage in the buying cycle.

Although Anavex Life Sciences» Alzheimer's disease program should offer up plenty of data to digest this year, its research program is very early stage, and the company's balance sheet is worrisome enough for me to avoid it until placebo - controlled trial results are available.

Most biotechs would have shuttered a clinical program that showed absolutely no efficacy whatsoever in a late - stage trial, but Novavax has instead doubled down on RSV by going forth with its phase 3 trial of the RSV F vaccine for infants via maternal immunization, and begun planning for another trial in older adults that's reportedly on track to kick off in 2018.

The Biblical accounts of God - to - human relationship and affairs going from the very obvious to the very mysterious, starting with creation and going through a multitude of stages, the fall, the expulsion and curse, trials and covenants, rebellion and Law, culminating with God's «Ultimate Provision» for Salvation, the «Good News» of the Lord Jesus Christ, His only begotten Son, the «New Covenant,» the «Millennial Kingdom» to come, the end of time, and the afterlife, are the basis for the Christian Theology on «Time Dispensations.»

The attentive reader can not fail to be struck with the amount of space allotted in them all to the closing stages of the story: the arrest, trial, and execution of Jesus, and the events immediately preceding and following.

Mechanization of red chile harvesting equipment is in the trial stage: less than 0.1 percent is harvested in this manner.

The Stage 20 climb of Alto de l'Angrliru comes shortly after the 40 - kilometer time trial to Logrono and a pair of summit finishes at Los Machucos and Santo Toribio.

Four riders are within 30 seconds of the yellow jersey with two major Alps stages and a time trial still to go.

Espinasse urged LeMond on during the 15th - stage time trial, from Gap to Orcières - Merlette, a 39 - km mountain climb of 5,633 feet.

Developed by a Boston - based company, SmartSports, the SmartKage has been in a trial stage over the past year «'' which led to its installation at the Concord baseball school, one of just 100 test sites chosen across the country.

New faces, voices, sensations, and scents are how babies learn — having to deal with the daily trials and tribulations of being ejected from the amniotic swimming pool is what helps babies mature from the admittedly adorable but somewhat potato-esque stage of life into thinking, rational beings.

Upright position during the first stage of labor: A randomized controlled trial.

There was no statistically significant difference in the frequency of postpartum hemorrhage among women undergoing immersion during the second stage of labor (RR, 0.14; 95 % CI, 0.10 — 2.71; one trial).

The 2009 Cochrane systematic review found no increase in maternal infections (RR, 0.99; 95 % CI, 0.50 — 1.96; five trials) with immersion during the first stage of labor.

Impact of breastpumping on lactogenesis stage II after cesarean delivery: A randomized clinical trial.

The second stage of transition or threshold marks the time in between states, involving something of a trial, a time of becoming — no longer connected to the old, but not yet established in the new.

Heart rate was recorded 2 minutes into each stage and was continuously monitored throughout the trial using a Polar RS300x heart rate monitor (Polar Electro Oy, Kempele, Finland) to capture maximum heart rate, which was used as a marker of appropriate effort.

Every stage of life has its trials and its blessings.