Because these organisms are excellent models for understanding stem cell biology, researchers were able to shed light on the earliest
stages of follicle cell differentiation, a previously poorly understood area of developmental biology.
Not exact matches
Hundreds
of follicles are estimated to be in various
stages of development at any given time.
In the ovary
of a normal mouse (left), a large
follicle is shown at a late
stage of development (a light pink oocyte surrounded by follicular cells, inset).
Mild hemorrhage
of ovarian
follicles (arrow) in the early
stage of infection (A); Severe hamorrhage and regression
of ovarian
follicles (B); HE stained ovary section, the
follicles ruptured and filled with round or granular eosinophilic bodies (C).
«It helps lengthen the active growing
stage of hairs and promotes healthy delivery
of oxygen and nutrients to the hair
follicle.»
Out
of this group, one
follicle (the dominant
follicle) is selected each month to proceed to the pre-ovulatory
stage while the rest undergo atresia.
Each month, during the reproductive years
of our lives, we activate a handful
of follicles to progress through the
stages toward producing an egg.
Studies show that the creation
of ovarian
follicles during this embryo
stage is exquisitely sensitive to the toxicity
of xenobiotics.
At this point the
follicle goes into a «resting»
stage for a period
of time before producing a new, healthy hair.
Both come from
follicles that go through four
stages of life: anagen, or growth; catagen, a transition phase; telogen, a dormant phase; and exogen, when hair and fur are shed.
Shedding, length
of hair and presence or absence
of an undercoat depend upon the timing
of these cycles and the ratio
of hair
follicles in the various
stages.
Hair shafts are absent, and hair
follicles are primarily in the telogen
stage of the growth cycle.