Sentences with phrase «stages of our treatment study»

Not exact matches

Lilly faced a devastating clinical setback last year with a late - stage failure for its experimental Alzheimer's treatment, the studies for which cost the company hundreds of millions of dollars.

Furthermore, an early - stage study pumping up the dose of its hemophilia A treatment — which aims to be a one - time therapy for the rare blood clotting - related disease — appeared to hit its targets without serious side effects.

In a late - stage study, Aimmune, a biotech immunotherapy allergy treatment taken via pill, found that of the roughly 500 kids with peanut allergies between the ages of 4 - 17 who were part of the trial, 67 % of those who received the treatment were able to tolerate 600 milligrams of peanut protein (about two to four peanuts) after about a year of treatment, while only 4 % of those who got the placebo could tolerate that dose of peanut protein.

Patisiran was being evaluated in a late - stage study against a placebo for the treatment of patients with hereditary ATTR (hATTR) amyloidosis with polyneuropathy.

The study discovered that stage 3 and 4 breast cancer women who supplemented their diet with virgin coconut oil during breast cancer treatment improved fatigue, dyspnea, sleep difficulties, and loss of appetite compared to the control group.

For the purposes of this economic evaluation, the forms were initially used in a related study funded by the National Institute of Health Research (NIHR) research for patient benefit programme «assessing the impact of a new birth centre on choice and outcome of maternity care in an inner city area,» which will be reported in full elsewhere, comparing the costs of care in a free standing midwifery unit with care in an obstetric unit in the same trust.16 The data collected included details of staffing levels, treatments, surgeries, diagnostic imaging tests, scans, drugs, and other resource inputs associated with each stage of the pathway through intrapartum and after birth care.

It is difficult at this stage to foresee the full impact of post-zygotic mutations in terms of treatment options for disease because the study was mainly focused on the technological aspects of these genetic changes, the researchers say.

There were very few studies comparing different types of psychosocial approaches, or assessing their effectiveness at different treatment stages and in different patient subgroups.

Our intention with this study was to assess Ipilimumab as an adjuvant treatment for patients with completely resected stage III melanoma at high risk of recurrence.

Prior studies that examined the impact of cancer treatment decisions on employment showed that patients who received chemotherapy were most likely to experience longer disruptions in or loss of employment, but changes in breast cancer management in recent years have shifted recommendations away from chemotherapy for early stage breast cancer.

The high prevalence of OSA the study found in these cognitively normal elderly participants and the link between OSA and amyloid burden in these very early stages of AD pathology, the researchers believe, suggest the CPAP, dental appliances, positional therapy and other treatments for sleep apnea could delay cognitive impairment and dementia in many older adults.

A recent study published in the Aug. 21, 2013 Journal of Bone and Joint Surgery, and conducted by health economists, has confirmed that TKR is a cost - effective treatment for patients with end - stage osteoarthritis.

His colleague Alex Liddle, an Arthritis Research UK clinical research fellow who ran the study, added: «Partial and total knee replacements are both successful treatments and a large proportion of patients with end - stage knee osteoarthritis are suitable for either.

Joseph Firth, the lead author on the study, said: «Establishing an exercise regime for people with psychosis is likely to be much more effective when they are younger, and in the earliest stages of treatment.

Results of a phase 2 study published in The Lancet suggest that simvastatin, a cheap cholesterol lowering drug, might be a potential treatment option for the secondary progressive, or chronic, stage of multiple sclerosis (MS), which is currently untreatable.

In the trial, co-led by Rachael Clark, MD, PhD, associate professor of Dermatology at Harvard Medical School, Alain Rook, MD, professor of Dermatology and director of the Cutaneous Lymphoma Program at Penn Medicine, and Joel M. Gelfand, MD, MSCE, associate professor of Dermatology and medical director of the Clinical Studies Unit at Penn Medicine, twelve patients who had previously undergone an average of six treatments for early stage CTCL were treated with topical resiquimod gel at varying doses and intervals.

A study of 172 women without depression and aged between 45 and 60 has found that a year of HRT treatment can help stop symptoms of depression emerging in women who are entering the menopause or who are in the early stages of post-menopause.

The study sets the stage for the development of more - sensitive and specific non-invasive tests for prostate cancer than those currently available, which could result in fewer unnecessary prostate biopsies with less treatment - related morbidity, according to a new study in The Journal of Molecular Diagnostics.

A multicountry study has found that HIV - infected people who start antiretroviral (ARV) treatment at earlier stages of the disease lowered their risk of transmitting the virus to their sexual partners by 96 %.

In the current study, a number of prognostic factors such as age, stage, comorbidity, hormonal receptor and HER2 status and differences in systemic treatments (medication after surgery) were included and considered as possible explanations for the previously reported survival differences between BCT and mastectomy.

While second - stage results showed no significant differences between participants continuing to receive weekly doses of the active drug, those receiving biweekly doses and those shifted to placebo, Kimball notes that, since it is typical for the severity of HS symptoms to increase and decrease and because the study protocol required treatment discontinuation for participants whose symptoms stopped responding to the drug, larger scale studies will be required to better define the ideal length and frequency of treatment.

Early - stage studies have implicated both pesticides for crops and for bees, in the form of treatments for Varroa mites.

The new studies find high activity with investigative drugs for advanced melanoma, and show for the first time that ipilimumab, a treatment already approved for advanced melanoma, can substantially decrease the risk of melanoma recurrence in certain patients with earlier - stage disease.

In this original article on the treatment of advanced stage Hodgkin lymphoma, the German Hodgkin Study Group updated their initial findings on the HD15 trial.

DENVER — Capturing and summarizing the remarkable progress in lung cancer prevention, diagnosis, staging, and treatment in 2015, the International Association for the Study of Lung Cancer (IASLC) announces the inaugural publication of «Scientific Advances in Lung Cancer 2015» in the May 2016 issue of the IASLC's Journal of Thoracic Oncology (JTO).

Although additional research is required to propel the embryo into the next stage - that of a live fetus - this study offers a more comprehensive understanding of early embryonic development and could help improve fertility treatments.

Higher inflammation and greater oxidative stress in diabetic women with end - stage renal disease, as well as modifiable gender differences in access to and modalities of treatment involved, were identified in some of these studies partly explaining excess mortality in diabetic women (319 — 322).

Phase 1 clinical trials give patients at University of Michigan access to pivotal early - stage studies, connecting families to novel treatment therapies to patients before they are widely available.

Additionally, the researchers say insights into the development of human eggs at various stages provided by the study could help research into other infertility treatments.

A new blood test that measures levels of two specific proteins may be able to accurately detect pancreatic cancer at its earliest stages, when it is most likely to respond to treatment, findings from a new study suggest.

One study conducted by researchers at Women's Healthy Eating and Living (WHEL) followed women who had completed treatment for early stage breast cancer, and found that women with the highest blood concentrations of carotenoids had the least likelihood of cancer recurrence.

After the Affordable Care Act eliminated out - of - pocket costs for mammograms, a significant uptick in cancers were caught during stage 1, when treatment is more effective, a new study found.

This is because the recently published EPIC1 study showed that early treatment with pimobendan in MVD Stage B2 dogs will delay the development of symptoms of congestive heart failure (CHF) by an average of 15 months.

BUT, we now know from the PROTECT2 study that in Dobermanns with early - stage DCM (i.e. heart enlargement on ultrasound but no symptoms of CHF), treatment with pimobendan delays the onset of CHF by an average of 9 months.

It is licensed for the treatment of the symptomatic stages of MMVD in all countries where the EPIC Study was conducted.

The study consisted of two stages of treatment: a preschool stage that began soon after birth and continued until five years of age, followed by a school - age stage from six to eight years of age.

Blended therapy is at an early stage of research, even though first studies date back to the 1980s and 1990s.18 — 20 At that time, computer support had been found to be useful in the treatment of depression, anxiety or obsessive compulsive disorders.20 However, these early studies do not adequately account for the rapid development that modern technologies have undergone, and user behaviour has changed dramatically since then.

Since this is a pilot study, and we hope to include as many caregivers as possible, no exclusion was made on the basis of care recipients» cancer type, cancer stage, time since first diagnosis or current treatment of patients.

Cecilia Saulters - Tubbs found that district attorneys were less likely to file charges against female drug offenders than against male offenders, while Donna Bishop and Charles Frazier found, similarly, that boys were treated more punitively than girls for delinquency offenses and that girls were less likely than boys to receive a sentence involving incarceration.10 Such studies suggest that the system treats girls as less criminally dangerous than boys.11 Other research, however, notes that once legal variables are controlled, girls are treated similarly to boys in the early stages of court processing but more harshly in the later stages.12 Earlier studies pointing toward more «chivalrous» treatment of girls may thus have failed to consider differences in the underlying seriousness of the offenses involved.

In an extension to the findings of Kernan and Lepore, the present results suggest that it is not only benefit finding in the early stages of cancer treatment that predicts later distress but that this longitudinal relationship is found across the six yearly assessment points in the present study [21].

For more than 30 years, research on the consequences of parental differential treatment, including favoritism and disfavoritism regarding parents» emotional resources, has been a major focus of interest in studies of families in the early stages of the life course.