Not exact matches
This is an obvious hurdle for longtime study» if the goal is to follow brain development for longer than a trimester or two prenatally, the
stage at which the current crop
of brain
organoids start to wither.
«The human
organoids are good for studying the very early
stages of brain development, but may not reveal much about later, more mature
stages on which things like sociality depend,» says John Mason at the University
of Edinburgh, UK.
«The
organoids are good for studying the very early
stages of brain development, but may not reveal much about later
stages on which things like sociality depend.»
These
organoids, as they are known, could provide new insights into the early
stages of pregnancy and conditions such as endometriosis, a painful condition that affects as many as two million women in the UK.
A more attainable goal may be regenerative tissue transplants, for example, replacing dying liver cells in someone with early -
stage liver disease with chunks
of healthy stem cells from a personalized liver
organoid.
Researchers had developed the technologies needed to create
organoids years before — how to grow cells in culture, how to isolate stem cells from human tissue, and how to coax the stem cells, undifferentiated and immature, to become specific types
of cells at later
stages of development.
Rodent models can't capture the years long path
of human brain development, but 3D human
organoids now give researchers a window into later
stages of development
of our burgeoning central nervous system.