Sentences with phrase «standard chemotherapy»
"Standard chemotherapy" refers to a common treatment method for cancer. It involves using drugs that can kill or slow down cancer cells in the body. This treatment is widely accepted and commonly used by doctors to help patients fight against cancer. Full definition
The vaccine was tested in a preliminary clinical trial and used with standard chemotherapy and an immune - boosting agent.
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In a comparison group of 56 patients who got standard chemotherapy alone, only half were still alive at the two - year mark.
The trial involves combining standard chemotherapy with a drug that has been found in laboratory studies to attack cancer stem cells.
These dormant stem cells have properties that allow them to resist standard chemotherapy, which is designed to defeat rapidly dividing cancer cells.
Based on this study's results, an international phase III trial of standard chemotherapy with or without ibrutinib in patients with DLBCL, excluding the GCB subtype, is being conducted by Janssen Pharmaceuticals, Titusville, New Jersey, in collaboration with Drs. Wilson and Staudt.
One American survey, she points out, showed that only 23 percent of patients lived longer than five years after failing to sustain remission with standard chemotherapy drugs.
Multiplexed genetic screening for epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) gene rearrangements and subsequent biomarker - guided treatment is cost - effective compared with standard chemotherapy treatment without any molecular testing in the metastatic non-small cell lung cancer (NSCLC) setting in the United States.
Researchers observed the efficacy of the antibody alone or in combination with standard chemotherapy in mouse models of NHL, MM, and AML.
While trilaciclib has a huge potential market among cancer patients receiving standard chemotherapies, investors want to keep their eyes on an ongoing trial evaluating a triple - combination of Roche's (NASDAQOTH: RHHBY) Tecentriq, chemotherapy, and G1's candidate.
As a precaution, she was started on epirubicin and cyclophosphamide — standard chemotherapy for breast cancer — and given radiotherapy.
A phase I study showed that azacitidine priming followed by standard chemotherapy could be an effective approach to resistance in patients with newly diagnosed diffuse large B - cell lymphoma (DLBCL).
Studies of standard chemotherapy regimens such as dacarbazine and paclitaxel / carboplatin showed response rates for mucosal melanomas that were comparable to those seen in cutaneous melanomas.
Merck's cancer immunotherapy Keytruda is one of the pharma giant's rising stars, especially in the wake of evidence that the therapy had a survival benefit over standard chemotherapy in advanced lung cancer patients.
The firm had even more positive results to present at the convention, announcing that Tecentriq shrunk tumors in 24 % of advanced bladder cancer patients who couldn't use standard chemotherapy in a mid-stage trial.
Prior to beginning this trial, these patients had failed to achieve remission on a median of 3.5 therapies including stem cell transplant, which, prior to BV, was the only potentially curative treatment for those who failed standard chemotherapy.
Rather than attacking and destroying replicating cells as standard chemotherapy drugs do, this therapy reprograms cells to behave more like normal cells.
«We do a phenomenal job with surgery, peeling off as much of the tumor as we can see, and then we do standard chemotherapy, but the cancers still recur,» Memarzadeh said.
When used alongside standard chemotherapy agents daunorubicin and cytarabine in a treatment - resistant AML model, 99.7 percent of cancer cells were killed.
And fifth, patients given IVC concurrently with standard chemotherapy report less fatigue, nausea, depression, sleep disorders, improved appetite, and improved overall wellbeing.
A randomized, phase II trial showed improved progression - free survival in small - cell lung cancer with maintenance sunitinib vs placebo following standard chemotherapy, according to results presented at the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago.
While standard chemotherapy drugs damage DNA to stop cancer cells from reproducing, the new method stops the source that creates those cancer cells: genes that are overexpressing certain proteins.
Patients were randomized to receive either nivolumab or a single type of standard chemotherapy until tumor progression was observed.
Patients receiving temozolomide, the current standard chemotherapy, had seven weeks of PFS and no tumor shrinkage.
It showed that those patients who received crizotinib did better with respect to improvement in symptoms and delay in growth of the cancer than those on standard chemotherapy.
In mice with pancreatic cancer, three days of fasudil treatment prior to standard chemotherapy increased survival time by 47 per cent.
For patients with cervical cancer that has recurred after treatment or has spread elsewhere in the body, adding the experimental drug cediranib to standard chemotherapy improves tumour shrinkage and adds a modest improvement in progression - free survival, researchers report at the ESMO 2014 Congress in Madrid.
«Experimental drug guadecitabine found safe in patients with colorectal cancer: Combination with standard chemotherapy shows promise in overcoming treatment resistance.»
NEW HOPE AGAINST RESISTANT BREAST CANCER: Ixabepilone, a compound being investigated by Bristol - Myers Squibb, shows some encouraging effectiveness against metastatic breast cancers that are resistant to three other standard chemotherapy drugs (anthracycline, taxane and capecitabine).
«Unlike standard chemotherapy, HIV - receptor blocking drugs have been proven to be safe and with rare side effects,» said Richard G. Pestell, MD, PhD, MBA, President of the Pennsylvania Cancer and Regenerative Medicine Research Center (PCARMRC).
Lead author Professor Ledermann, professor of medical oncology at the UCL Cancer Institute and a Cancer Research UK grantee, said: «A well - tolerated anti-tumour agent that could be used for months or perhaps years as maintenance therapy after standard chemotherapy could be a big step forward and ultimately extend survival.
The idea of adding the targeted EGFR inhibitor cetuximab (Erbitux) to standard chemotherapy took a hit, as results from the SELECT phase III trial showed no improvement in efficacy when cetuximab was combined with pemetrexed in patients with recurrent or progressive non — small - cell lung cancer (NSCLC).
Docetaxel is one of two standard chemotherapy treatments used in patients whose disease has progressed after they have already received platinum - based chemotherapy.
That means they have a high likelihood of disease recurrence and poor survival odds despite receiving standard chemotherapy and optimum surgery.
This company's lead candidate, trilaciclib, is intended to prevent the blood cell devastation often caused by standard chemotherapies, and it appears to do the trick.
When results of treatment with standard chemotherapy alone versus chemotherapy plus Herceptin were compared, it was found that tumors shrank at least 50 percent in half the women getting chemotherapy with Herceptin, compared with one - third of women receiving chemotherapy alone.
«These studies suggest the potential for dramatically reducing the dose of chemotherapy or radiation and thereby reducing the side effects of standard chemotherapy by enhancing the targeting of cancer therapies using HIV receptor blocking drugs.»
This drug is ideally used with standard chemotherapy regimens.
Studies have shown that TKI treatment is better than conventional chemotherapy in terms of progression - free survival (PFS) among patients with these EGFR mutations; it is not clear that EGFR TKIs are as effective as standard chemotherapy in patients without EGFR mutations, according to background information in the article
«But the positive effect on progression - free survival in this phase III study confirms that there is greater benefit using a second ALK inhibitor over standard chemotherapy.
The targeted radiotherapy shrank tumors for 71 % of patients who had already failed standard chemotherapy, but these results came from a small trial that started with 30 patients and then added another 20 after positive data started rolling in.
Thanks to proceeds from the ride, researchers have identified a subset of non-Hodgkin's lymphoma cells that resist standard chemotherapy and can cause cancer to recur.
Standard chemotherapy agents don't work specifically on blocking retinoblastoma tumors but instead broadly inhibit DNA replication.
This makes the starter materials for synthesizing the complex far more economical than a number of industry - standard chemotherapy drugs based on platinum.
Graham looked to the Internet for treatment options and came across Duke University oncologist Keith Sullivan, who was comparing standard chemotherapy and stem cell therapy as part of a large - scale clinical trial for scleroderma.
The current study examined the impact of CRS - 207 combined with standard chemotherapy in patients with advanced unresectable mesothelioma who were candidates for chemotherapy.
That's not just because of Opdivo's failure — last month, Keytruda was shown to be better than standard chemotherapy in untreated advanced lung cancer patients with high levels of the PD - L1 protein, both stopping cancer progression and extending patients» lives.
The company said a late - stage trial of its cancer drug Abraxane met its main goal of improving the patient's time of survival without worsening skin cancer, when compared to standard chemotherapy.