Sentences with phrase «standard chemotherapy treatment»

In a study presented today at a meeting of women's cancer specialists, overall survival for women who received standard chemotherapy treatment plus bevacizumab was a median five months longer than for women who received the standard chemotherapy treatment alone.

Dr Fiona Blackhall, a senior lecturer in The University of Manchester's Institute of Cancer Sciences and a consultant based at The Christie NHS Foundation Trust — both part of the Manchester Cancer Research Centre — said: «In order to introduce precision medicine, where each cancer patient receives treatment designed to target the genetic makeup of their individual cancer, we need to compare how effective the new targeted treatment is compared to standard chemotherapy treatment.»

Multiplexed genetic screening for epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) gene rearrangements and subsequent biomarker - guided treatment is cost - effective compared with standard chemotherapy treatment without any molecular testing in the metastatic non-small cell lung cancer (NSCLC) setting in the United States.

Not exact matches

«I hope that someday all of you on the advisory committee can tell your families for generations that you were part of the process that ended the use of toxic treatments like chemotherapy and radiation as standard treatment, and turned blood cancers into a treatable disease that even after relapse most people survive.»

Paclitaxel and another chemotherapy drug, carboplatin, are considered standard, first - line treatments for advanced ovarian cancer, experts say, and most patients respond to the drugs initially.

«iCCA is resistant to standard treatments like chemotherapy and radiation,» said Josep Maria Llovet, MD, Director of the Liver Cancer Program, Division of Medicine, Icahn School of Medicine at Mount Sinai, and contributing author.

For decades most cancers have been treated with a core standard of treatments that include surgery, radiation, and chemotherapy.

Additionally, due to other medical issues or poor performance status (a measure that considers a patient's quality of life and ability to function during treatment), some stage III NSCLC patients are unable to receive the standard treatment of concurrent chemotherapy and RT..

Dr. Dick says: «Our new findings add to that knowledge and we hope that we will soon have a new biomarker that will tell whether a patient will respond to standard chemotherapy, and then another to track patients in remission to identify those where treatment failed and the rare leukemia stem cells are coming back.

Of the dogs stricken with osteosarcoma, 35 had the cancer in a leg which was subsequently amputated, followed by chemotherapy, which is the standard - of - care treatment; the dogs with elevated total cholesterol had a median survival time of 455 days, more than 200 days greater than the median survival time for dogs with normal cholesterol.

«Standard of care treatment with pemetrexed and platinum compound chemotherapy gets a 30 % response rate but a modest impact on survival.

According to the study authors, the results are especially impressive because half of the patients had just finished treatment with the standard class of chemotherapy agents — fluoropyrimidines (e.g. 5 - fluorouracil [5 - FU] or capecitabine [Xeloda]-RRB- but had failed to benefit from them.

Neoadjuvant chemotherapy, given for five to six months before surgery, is the standard treatment for some women with newly diagnosed invasive, but operable, breast cancer.

When he and his colleagues gave the mice the standard, maximum tolerated dose of the chemotherapy drug paclitaxel, the tumours roared back as soon as the treatment was stopped.

«Although some non-small cell lung cancer patients have increased benefit of targeted therapy or immunotherapy instead of chemotherapy, for some groups of patients with NSNSCLC, chemotherapy has been the standard treatment for more than 30 years,» Gandhi notes.

With standard treatments of surgery, chemotherapy and radiation, the median survival time is only 14.6 months, and improvement will only come with the ability to kill tumor cells resistant to standard treatments, according to Alfredo Quiñones - Hinojosa, M.D., a professor of neurosurgery at the Johns Hopkins University School of Medicine and a member of the research team.

To study nanodiamonds» usefulness for cancer treatment, Ho's group attached them to doxorubicin, a standard chemotherapy drug, and injected them into mice with drug - resistant breast and liver cancer.

Exploiting the same pre-clinical model used for their studies, the researchers are testing the efficacy of this kind of drug candidates against cancer stem cells, and the possibility of identifying combination regimens with standard chemotherapies with minimized toxic effects, with the perspective of their possible application for the treatment of human breast cancer.

It is the first time a therapy has improved progression - free survival over the current standard first line treatment with platinum - based doublet chemotherapy.»

The strong response to this new use of enzalutamide shows that it can provide a viable, less toxic alternative to chemotherapy in staving off the disease in men who aren't responding to standard first line hormonal treatments,» said Tomasz Beer, M.D., the lead author on the study and deputy director of the Knight Cancer Institute at OHSU.

Graham looked to the Internet for treatment options and came across Duke University oncologist Keith Sullivan, who was comparing standard chemotherapy and stem cell therapy as part of a large - scale clinical trial for scleroderma.

In elderly cancer patients like my father and aunt, who suffer from a variety of chronic health problems, physicians often modify standard treatment regimens — perhaps using two chemotherapy drugs instead of three or lowering standard dosages — in the hope that the revised treatment will work well enough.

In mice with pancreatic cancer, three days of fasudil treatment prior to standard chemotherapy increased survival time by 47 per cent.

Two patients that had previously not responded to available standard treatments, including surgery, external radiation, hormonal and chemotherapy, have received 225Actinium - PSMA - 617 as experimental therapy.

Because AML is difficult to treat, standard treatment commonly involves multiple chemotherapy medicines that are given at a higher dose in order to kill the cancer cells.

But in the meantime, it would help if we could identify who won't benefit from standard treatment, so we can spare them the debilitating effects of chemotherapy and get them into clinical trials for experimental therapies that might be more effective.»

Percentage of total body fat and lean muscle mass was measured directly, using the gold standard of dual - energy X-ray absorptiometry (DXA) at time of diagnosis, one month later, and later during chemotherapy treatment.

For patients with cervical cancer that has recurred after treatment or has spread elsewhere in the body, adding the experimental drug cediranib to standard chemotherapy improves tumour shrinkage and adds a modest improvement in progression - free survival, researchers report at the ESMO 2014 Congress in Madrid.

The standard treatment for glioblastomas consists of removing as much of the tumor as possible with surgery and then eliminating what is left through radiotherapy combined with chemotherapy.

Currently, the ABVD chemotherapy regimen is the gold standard for treatment of Hodgkin's disease.

In all instances, treatments involving the antibody — whether alone or in combination with chemotherapy — appeared to eradicate more cancer cells compared to standard care.

When used alongside standard chemotherapy agents daunorubicin and cytarabine in a treatment - resistant AML model, 99.7 percent of cancer cells were killed.

Although CSs comprise only 2 % -5 % of all uterine malignancies and 1 % -2 % of all ovarian tumors, they are responsible for a disproportionate number of deaths due to their high biologic aggressiveness and resistance to standard treatments, such as radiation and chemotherapy.

«This is a promising treatment option that may prove not only to be more effective than chemotherapy alone prior to surgery, it may also be better than chemotherapy and standard radiation,» said lead study author Kimmen Quan, MD, a radiation oncologist at the University of Pittsburgh Medical Center.

The standard treatment of locally advanced cervical cancer is EBRT with concurrent chemotherapy, followed by brachytherapy.

«Prostaglandin EI inhibits leukemia stem cells: Targeting leukemia stem cells in combination with standard chemotherapy may improve treatment for chronic myeloid leukemia.»

The research involves patient volunteers whose cancer has returned or did not respond to standard treatment, which for neuroblastoma includes surgery, chemotherapy, radiation and bone marrow transplants.

Standard treatment is surgery, followed by radiation therapy and chemotherapy with temozolomide.

Many standard cancer treatments, including chemotherapy drugs and radiation therapy, damage the DNA of rapidly dividing cancer cells.

The standard first - line therapy treatment involves chemotherapy, and currently there is no approved second - line therapy.

Pembrolizumab is approved for the treatment of both squamous and non-squamous non-small cell lung cancer (NSCLC) that is no longer responding to standard - of - care chemotherapy.

Treatment of pediatric Ph + ALL with a combination of standard chemotherapy and RTK inhibitors may result in remission, [citation needed] but the curative potential is unknown.

Standard treatment for children with medulloblastoma consists of surgery in combination with radiation and chemotherapy.

But these epigenetic drugs have shown some success in improving patients» response to chemotherapy or immunotherapy, or in overcoming resistance to those standard treatments.

Chemotherapy is a key part of the standard treatment regimen for triple - negative breast cancer patients whose cancer lacks expression of estrogen and progesterone receptors and the human epidermal growth factor receptor 2...

When Brenda Berchtold, 51, was first diagnosed with triple - negative breast cancer in 1986, her treatment options were limited: surgery, radiation, and chemotherapy were the gold standard.

It is a scary diagnosis, and even though chemotherapy can be effective as standard - of - care, many patients become resistant to treatment.

The international early Phase II trial led by a team based at the Oxford Cancer Research Centre will trial the experimental drug called LY2181308 with advanced non-small cell lung cancer patients who no longer respond to platinum chemotherapy - the standard initial treatment for this group.

Voice - Box Saved with New Larynx Cancer Therapy Standard therapy changes for larynx cancer, and, the voice box is spared, after Kimmel Cancer Center investigators prove that, for most patients, combined treatment with chemotherapy and radiation has the same success rate as surgically removing the cancerous voice box.

This is a patient who we knew had, at best, a 1 in 10 chance of having a complete remission following treatment with standard chemotherapy, but who is now getting treated with commercially available axi - cel.