Again, ApoC - III ASO treatment had no effect on plasma TG levels in mice lacking both Lrp1 and Ldlr (Figure 5, A and C), as observed with animals fed
a standard chow diet (Figure 1) and under postprandial conditions (Figure 3).
The recipient mice were maintained in a pathogen - free facility and were fed
a standard chow diet and water supplemented with 0.5 ml / l of 10 % Baytril (Bayer Corp., Shawnee Mission, Kansas, USA).
Not exact matches
The study was conducted in rats, which included 24 pregnant subjects; 12 were fed
standard chow and 12 were fed a high - fat
diet, similar to the typical American
diet.
«Importantly, we found that blocking the actions of the endocannabinoids with pharmacological inhibitors of cannabinoid receptors in the periphery completely normalized food intake and meal patterns in western
diet - induced obese mice to levels found in control lean mice fed
standard chow.»
Interestingly, Xiong et al. further showed that the GDF15 regimen altered food preferences in mice — leading the animals to opt for lower calorie
chow when offered a choice between
standard food and an extra-rich condensed - milk
diet (untreated mice gorged themselves on the high - calorie eats).
Mice were weaned at 3 weeks, maintained on a 12 - hour light cycle, and had ad libitum access to water and a
standard rodent
chow diet (PicoLab Rodent
Diet 20, 5053; LabDiet) or a high - fat
diet (TD.88137; Harlan Teklad).
One study has tested the efficacy of IER (100 % ER / alternate days) in preventing the development of high - fat
diet - induced insulin resistance (IR).54 In this study, rats received ad libitum access to either
standard (control) or high - fat
chow.
CB1 antagonists have been shown to decrease nicotine self - administration in rodent models of nicotine dependence.24 While CB1 agonists increase feeding in rats and humans, CB1 antagonists have been shown to have the opposite effect, significantly suppressing rats» food intake regardless of type of
diet (
standard lab
chow, high fat or high carbohydrate).
His lab has done studies in rats, where they compared mice fed a
standard diet (rat
chow) with mice fed a fattening
diet, for 7 days.