Sentences with phrase «standard combination chemotherapy»

To meet these aims, we will enroll 20 dogs with untreated DLBCL and treat them with standard combination chemotherapy (CHOP).

(In clinical trials, HER2 - positive patients receiving Herceptin and standard combination chemotherapy had a 52 percent decrease in disease recurrence compared with patients treated with chemotherapy alone.)

Not exact matches

While trilaciclib has a huge potential market among cancer patients receiving standard chemotherapies, investors want to keep their eyes on an ongoing trial evaluating a triple - combination of Roche's (NASDAQOTH: RHHBY) Tecentriq, chemotherapy, and G1's candidate.

The combination of drugs appeared less toxic than standard chemotherapy, were relatively inexpensive and should be clinically evaluated, said Dwayne G. Stupack, PhD, the study's senior author and associate professor in the dDivision of Gynecologic Oncology at Moores Cancer Center.

The researchers then used a combination of existing United States Food and Drug Administration - approved drugs to target autophagy and found ovarian cancer cells to be highly sensitive to these drugs in several different mouse cancer models — even among cells resistant to standard chemotherapy.

Exploiting the same pre-clinical model used for their studies, the researchers are testing the efficacy of this kind of drug candidates against cancer stem cells, and the possibility of identifying combination regimens with standard chemotherapies with minimized toxic effects, with the perspective of their possible application for the treatment of human breast cancer.

In all instances, treatments involving the antibody — whether alone or in combination with chemotherapy — appeared to eradicate more cancer cells compared to standard care.

Researchers observed the efficacy of the antibody alone or in combination with standard chemotherapy in mouse models of NHL, MM, and AML.

«PF - 06747143 could potentially be used as a standalone therapy for patients who are not candidates for standard care or used in combination with chemotherapy,» noted Dr. Pernasetti.

«Prostaglandin EI inhibits leukemia stem cells: Targeting leukemia stem cells in combination with standard chemotherapy may improve treatment for chronic myeloid leukemia.»

Researchers have found that people with advanced head and neck squamous cell carcinoma and the KRAS - variant inherited genetic mutation have significantly improved survival when given a short course of the drug cetuximab in combination with standard chemotherapy and radiation.

Treatment of pediatric Ph + ALL with a combination of standard chemotherapy and RTK inhibitors may result in remission, [citation needed] but the curative potential is unknown.

Standard treatment for children with medulloblastoma consists of surgery in combination with radiation and chemotherapy.

To combat the nation's third deadliest cancer, the phase 1b / 2 open - label study will explore the combination of standard chemotherapy and two immunotherapy agents: an anti-PD-1 checkpoint inhibitor and a novel antibody targeting CD40, a protein that when activated can drive the immune system to attack tumors.

The standard of care for locally advanced, which is usually treated by radiation and chemotherapy combination.

The present standard of care for canine lymphoma consists of multiagent systemic chemotherapy combinations.