Sentences with phrase «statin studies»

Statin studies are generally performed by cardiologists and in the U.S., many statin studies reported only heart attacks and other cardiovascular events as endpoints, not total mortality, cancer, or infectious disease.

Beatrice Golomb is an M.D. Ph.D. who heads up the UCSD Statin Study group, a research team who are actively investigating the risk - benefit balance of statin drugs.

Not exact matches

REDUCE - IT is the first multinational cardiovascular outcomes study evaluating the effect of prescription pure EPA therapy, or any triglyceride - lowering therapy, as an add - on to statins in patients with high cardiovascular risk who, despite stable statin therapy, have elevated triglyceride levels (150 - 499 mg / dL).

A 2005 study in the American Journal of Clinical Nutrition found that consuming almonds as part of a heart - healthy diet can be just as effective at lowering LDL «bad» cholesterol levels as first generation statin drugs.

You might have also noticed that Statin Drugs have come under a negative light in some studies.

A new study shows that the drug fenofibrate might reduce the risk of cardiovascular events in patients with type 2 diabetes who have high levels of triglycerides and low levels of «good» cholesterol, despite being treated with statins.

In 2007 Karas published a study in the Journal of the American College of Cardiology suggesting that the risk of complications increases with statin dose.

A study concludes that including actual statin drugs with high - fat restaurant meals is a justifiable public health effort.

After all, only after 30 years of study did researchers discover that statins could raise the risk of type 2 diabetes.

Studies following the scandal suggested that statins might impede protection from oxidative stress or alter other chemical reactions in muscle cells.

However, during the non-blinded phase of the study, muscle - related symptoms were 41 % more common among people taking statins compared to those who weren't (1.26 % vs 1.00 % per year respectively).

THE STATIN UMBRELLA After decades of study, a big question remains about the safety of statins: What are the risks for people who have a chance of benefit but haven't yet had a heart attack or stroke?

In one routine - care study, reported in 2013 in Annals of Internal Medicine, 8 percent of patients stopped taking statins because of side effects.

«We found that almost 50 per cent of women in their late seventies and eighties in the study took statins, and five per cent were diagnosed with new - onset diabetes,» Dr Jones said.

Thus, the strengths of Gupta and colleagues» study lie in the fact that these were the same patients, no run - in period existed to exclude patients intolerant to therapy, and few patients had previously taken any statins.

Older Australian women taking cholesterol - lowering statins face a significantly increased risk of developing diabetes, according to a University of Queensland study.

The study looks at data on 26 side effects from a trial of approximately 10,000 patients and suggests that cases of muscle pain and weakness are unlikely to be directly caused by statins, but may instead be due to the so - called nocebo effect, where the expectation of side effects can make patients more likely to report them.

«Statins are arguably the most widely studied medicines ever,» says Jeremy Sussman, a primary care provider at the University of Michigan and the Department of Veterans Affairs in Ann Arbor.

Studies even floated the idea that statins could protect against cancer and influenza (SN: 5/5/12, p. 30).

«No association between «bad cholesterol» and elderly deaths: Systematic review of studies of over 68,000 elderly people also raises questions about the benefits of statin drug treatments.»

Diamond and colleagues have published a number of studies relating to the use and possible misuse of statins for treating cholesterol.

Those studies, including their recent paper published in the medical journal Expert Review of Clinical Pharmacology, which demonstrated that the benefits of taking statins have been exaggerated and are misleading.

Half of the people eligible for statins had no sign of plaque on CT scans of their hearts, and such people rarely suffered a heart attack in the next decade, according to a new study published in the Journal of the American College of Cardiology.

A study by investigators at Brigham and Women's Hospital (BWH) published this week in PLOS ONE identifies four factors that may account for sex differences in statin therapy among patients with coronary artery disease (CAD), pointing to interventions and additional research that will be needed to help overcome this sex disparity and reduce cardiovascular risk for women.

«This is the first study to identify factors that explain almost all of the sex disparities in statin therapy,» said corresponding author Alexander Turchin, MD, MS, a physician and researcher in the Division of Endocrinology at BWH.

Lipids are integral to the central nervous system, and as studies of statins and diabetes drugs have shown, dropping levels of some lipids can have deleterious cognitive effects.

Dr. Criner said that despite the clinical trial's finding that the statin drug did not help with COPD flare - ups, information gleaned from this study should help inform other research into the inflammatory nature of COPD.

The study also showed that acute pancreatitis was more common in statin users than non-users.

The study enrolled patients with moderate to severe COPD who were not taking statins for other medical indications.

The study also analysed the association of pancreatitis with the use of cholesterol - lowering drugs, statins, as gallstones often contain crystallised cholesterol.

The study rigorously tested the hypothesis that statin drugs may be beneficial to persons with COPD because of the drugs» purported anti-inflammatory effect.

Animal studies have shown statins to dissolve gallstones.

The small study, based on a survey of 236 cardiologists and internal medicine physicians and trainees at a large tertiary academic medical center, found that although physicians rate nutrition to be as important as statins in terms of reducing the risk of cardiovascular disease, only 13.5 percent agreed or strongly agreed that they were adequately trained to discuss nutrition with patients.

Over the past few years, many studies have shown that statins prevent heart disease and stroke, saving lives.

Darshak Sanghavi, chief of pediatric cardiology at the University of Massachusetts Medical School in Worcester, notes that although the FDA has approved some statins for use in children with a genetic problem leading to high cholesterol, there are no studies on the drugs» long - term side effects in children.

The use of statins may not be associated with lowering risk for Parkinson's disease, according to a new study led by researchers at Penn State College of Medicine and National Institute of Environmental Health Sciences.

«We hope that these findings will provide motivation to study how statins not only affect asthma symptoms but more specifically viral - induced asthma exacerbations.»

«Moreover, statin use over the course of the study did not protect against PD, and in fact appeared to increase PD risk in the long term.

The use of statins has also been associated with a lower incidence of PD in several recent epidemiology studies, leading some researchers to hypothesize that these medications, which lower levels of LDL — bad cholesterol — may protect against PD.

Those studies, however, failed to account for cholesterol levels prior to the widespread use of statins in the U.S. population, Huang said, noting that as a strength of the new study.

«Some previous research has suggested that treating patients with statins after they suffer hemorrhagic stroke may increase their long - term risk of continued bleeding,» said lead author Alexander Flint, MD, PhD, of the Kaiser Permanente Department of Neuroscience in Redwood City, Calif. «Yet the findings of our study suggest that stopping statin treatments for these patients may carry substantial risks.»

Patients who were treated with a statin in the hospital after suffering from a hemorrhagic stroke were significantly more likely to survive than those who were not, according to a study published today in JAMA Neurology.

This study was conducted by the same researchers who recently discovered that the use of cholesterol - lowering statins can improve survival in victims of ischemic stroke.

«This policy allowed us to see whether there was any difference in the risk of Parkinson's in people who stopped taking statins compared to the ones who kept taking them,» said study author Jou - Wei Lin, MD, PhD, of National Taiwan University in Taipei.

Previous studies on the relationship between cholesterol drugs called statins and the risk of Parkinson's disease have had inconsistent results.

Intriguingly, the study also found that drugs called statins, which are better known for their cholesterol - lowering properties, appeared to alleviate the effects of telomere damage — and may even have protected telomeres against degradation.

The current study involved 43,810 people in Taiwan who were taking statins and did not have Parkinson's disease.

Dr Nakano said: «Our study shows that CAD patients with very low LDL - C levels at initial presentation also benefit from statin treatment.

The most thorough study to date had some 3,000 men with «high» cholesterol levels take a statin every day for five years, while 3,000 similar men took a placebo.

In an accompanying editorial, Daniel C. DeSimone, MD, of the Division of Infectious Diseases, and Christopher V. DeSimone, MD, PhD, of the Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, expand on the importance of the study's findings and provide additional insights with more details about S. aureus infections and statin pharmacology, and put these findings into clinical context.