Sentences with phrase «statin use»

Dr Nakano concluded: «The next step should now be to initiate a randomised controlled trial of statin use in patients with CAD and very low LDL - C levels.

Although the analysis on statin use and PD was based on a fairly small number of PD cases, this preliminary data argues against the hypothesis that statins protect against PD.»

«Statin use during hospitalization for hemorrhagic stroke associated with improved survival.»

«Rather, this study should alert researchers, [clinical] guideline writers, and policymakers that short - term clinical trials might not fully describe the risks and benefits of long - term statin use for primary prevention.»

If we can prevent side effects from long - term statin use, we are improving health outcomes for millions of people.

«There might be a subset of COPD patients who might benefit from statin use who don't need a statin for cardiovascular reasons, but the heart and lungs are intertwined, and it's hard to tease out someone with COPD who doesn't have risk factors for cardiovascular disease,» Horovitz said.

New recommendations to expand statin use will save lives but also raise questions about aggressively treating the healthy

The anti-inflammatory effects of the ubiquitous statins used to lower cholesterol are also being contemplated.

Stroke rates seem to decrease most sharply after year 1998, approximately when statin use became more prevalent,» explains Dr. Fang.

«Moreover, statin use over the course of the study did not protect against PD, and in fact appeared to increase PD risk in the long term.

The new guidelines recommend statin use for some patients without high cholesterol but who have other risk factors for heart disease and stroke.

Cholesterol readings were taken at three - year intervals over the course of a decade from 1987 to 1989, before widespread statin use began.

The team also investigated the risk of infection while taking into account the duration of current or former statin use, 90 - day cumulative dose, and specific sub-groups of patients who were prescribed statins for different chronic conditions like previous myocardial infarction, peripheral arterial disease, chronic heart failure, chronic kidney disease, and diabetes.

He said statin use alone might help, but perhaps not enough, since tumors could simply rev up the regulation of the cholesterol manufacturing process in tumors to compensate.

A famous Danish study of neuropathy as a side effect to statin use concluded that an individual who is a long - term user of statin drugs has anywhere from 4 to 14 times greater risk of developing peripheral neuropathy than a person who does not take statin drugs.

Statin use also has been linked to a reduced rate of kidney stone formation.

One indication may be if you're currently taking statins, or struggling with adverse effects caused by previous statin use.

Our bodies naturally produce less CoQ10 as we age, and statin use compounds the issue even more.

They found that women were less likely than men to have been evaluated by a cardiologist, one factor that may contribute to lower rates of statin use.

This study comes on the heels of a separate large - scale investigation that found no link between statin use and the number of COPD exacerbations people experienced.

People on statins used to undergo periodic liver enzyme testing.

Overall, these four factors accounted for 90 percent of the differences seen between women and men in statin use, and point to possible interventions to help overcome this disparity.

The risk was especially elevated during the first year of statin use.

In a nationwide study, statin use was found to significantly increase the risk of acute pancreatitis.

Half the statins used worldwide are used in the United States, and that was before the 2001 and 2004 updates of the National Cholesterol Education Program recommended more than tripling the number of Americans taking statin therapy.

Older age, male gender, cirrhosis and diabetes also were independently associated with an increased risk, but nucleos (t) ide analogue or statin use was associated with a decreased risk.

The researchers concluded that statin use is strongly associated with improved outcomes after hemorrhagic stroke, and that discontinuing statin use is strongly associated with worsened outcomes after hemorrhagic stroke.

«One possibility,» Huang said, «is that statin use can be a marker of people who have high cholesterol which itself may be associated with lower PD risk.

Statin use is widespread in middle - aged and older individuals, who also have an increased risk of AMD; however, previous studies have shown very little correlation between regular statin use and improvements in AMD.

Researchers report that statin use, especially among elderly patients with preexisting chronic conditions such as diabetes, kidney, or liver disease, may be protective against this serious bloodstream infection.

Statin use may also lead to:

«Statin use appears to reduce risk of serious bacterial bloodstream infection: New study shows that statin use was associated with decreased risk of blood infection with Staphylococcus aureus acquired outside of a hospital.»

Their findings, published in the journal Atherosclerosis, showed a statistically significant inverse association of both the number of HDL particles (HDL - P) and the concentration of small and medium - sized HDL particles (MS - HDL - P) with coronary artery calcification, after adjusting for age, statin use, smoking, and other factors.

«In our study, statin use was associated with a significantly higher risk of new - onset diabetes, even in a very healthy population,» says lead author Dr. Ishak Mansi.

Mansi urges further trials, similar to his group's, to better understand the long - term effects of statin use.

In the study, statin use was also associated with a «very high risk of diabetes complications,» says Mansi.

«While evidence from a recently completed [randomized controlled trial] suggested that statin use is of little benefit to COPD patients, this population - based analysis showed that statin use reduced all - cause mortality among COPD patients,» wrote the study authors led by Adam Raymakers, from the University of British Columbia.

Graveline also points out that statins are useful for secondary prevention of heart disease in patients with significant pre-existing coronary artery disease (link), however the benefit is independent of cholesterol response during statin use.

• In this 2009 study, statin use was associated with a rise of fasting plasma glucose in patients with and without diabetes, independently of other factors such as age, and use of aspirin, β - blockers, or angiotensin - converting enzyme inhibitors.

The following scientific reviews also reached the conclusion that statin use is associated with increased incidence of new - onset diabetes:

Dr. Carloyn Dean, Medical Advisor of the Nutritional Magnesium Association, concluded, ``... heart disease is still the number one killer in America, in spite of over two decades of statin use.

Crestor Linked To Patient Death — Statin Drugs Safety Questioned Astra Zeneca, the maker of cholesterol lowering statin drug Crestor, has confirmed that a patient died of rhabdomyolysis, a potentially fatal muscle wasting disease linked to statin use, but says that the drug «is safe», reports WebMd.

«Whole - grain intake and statin use were also significantly linked with healthier total cholesterol / HDL - cholesterol ratios and total cholesterol concentrations,» she added.

According to one recent study, just 30 days of statin use can decrease CoQ10 levels by up to 50 percent.