Sentences with phrase «stem cell behavior»

«Martin's vision for genetic analysis of pluripotency, afforded by our extensive mouse resources, could lead to major advances in our understanding and manipulation of stem cell behavior in health and disease.»

Similar to the naturally occurring effects of TET2 mutations in mice or humans, using molecular biology techniques to turn off TET2 in mice caused abnormal stem cell behavior.

In the adult central nervous system, the vasculature of the neurogenic niche regulates neural stem cell behavior by providing circulating and secreted factors.

Nanofiber orientation and surface functionalization modulate human mesenchymal stem cell behavior in vitro.

We have a particular focus on glycosaminoglycans and have studied the role of heparan sulphate in embryonic stem cell behavior.

Martin's vision for genetic analysis of pluripotency... could lead to major advances in our understanding and manipulation of stem cell behavior in health and disease.

The research team led by Prof. Fiona Doetsch at the Biozentrum of the University of Basel has now shown that the choroid plexus is a key component of the stem cell niche, whose properties change throughout life and affect stem cell behavior.

«The more we know about the molecules that govern stem cell behavior, the closer we will get to controlling these cells.»

The researchers also discovered an essential role for the mechanical properties, i.e. the physical stiffness, of the gel in regulating intestinal stem cell behavior, shedding light on how cells are able to sense, process and respond to physical stimuli.

The study recently published in «Cell Stem Cell» also shows that signals secreted by the choroid plexus dynamically change during aging which affects aged stem cell behavior.

Effects of telomerase and telomere length on epidermal stem cell behavior.

«Our study demonstrates an important mechanism by which chronic inflammation induces abnormal stem cell behavior,» says Freddy Radtke.

In addition, we wish to characterize how variations in neural stem cells behavior may account for the large expansion of the human brain, but also how alterations may lead to pathological brain development.

He graduated magna cum laude from Cornell University in 2003 with a degree in biochemistry, and received his PhD from Princeton University in 2009 for work on the effects of extracellular matrix proteins on embryonic stem cell behavior.

Identifying the reasons for reduced upd expression could reveal how aging leads to changes in stem cell behavior, and counteracting these changes may slow the loss of adult stem cells during aging.

They observe that different regions of the gut are more susceptible to tumorigenesis upon inhibition of Notch signalling, suggesting regional differences in stem cell behavior.