Sentences with phrase «stem cell block»

Not exact matches

He decreed that the case brought by researchers Drs James Sherley and Theresa Deisher, along with a number of Christian groups including the Christian Medical Association, should be heard; and ordered an injunction temporarily blocking federal funding allocated for human - embryonic - stem - cell research.

Cord blood includes potent stem cells, which are considered to be the building blocks of the body.

Recently it has been shown that it also contains stem cells, the universal building blocks for growth and development.

Stem cells are unique because they are essentially the body's building blocks; these are the only cells in the human body that have the ability to regenerate more cells with specialized functions.

Mr Blair also used his trip to California to woo researchers in stem cell science to come to the UK, after Mr Bush used his first presidential veto to block the further expansion of federal investment in this area of research.

This protein overload leads to unbalanced stem cell growth and dramatically blocks differentiation to blood cells.

«Several unusual nucleobases have been found in the genomes of stem cells, which are produced by targeted chemical modification of the known building blocks of DNA.

On to the blocks were poured a mixture of recombinant human bone morphogenic protein (BMP) powder — a genetically engineered protein that causes cells to ossify or become bone — and liquid bone marrow containing stem cells.

The researchers confirmed this hypothesis by showing that if they blocked YAP1 they could inhibit stem cells from undergoing self - renewal, forming blood vessel - like structures, and reduce lung cancer cell growth in mice.

Drosha degrades the messenger RNA for NFIB in the adult hippocampal stem cells and prevents the expression of this transcription factor which is necessary for the differentiation of oligodendrocytes and thus blocks their development and therefore biases differentiation towards neurons.

Studying mice with injuries to the lining of the stomach, the researchers blocked the animals» ability to call on stem cells for help in the stomach.

They were able to block proliferation of several cancer stem cell lines.

► On Wednesday at ScienceInsider, Tania Rabesandratana reported from Brussels that the European Commission has denied a request by a citizens» initiative to «block E.U. funding for research using embryonic stem cells.»

«In order to block tumor recurrence after radiation therapy, we used an antibody to target and inhibit these cancer stem cells,» said Dr. Xu.

«The EPF2 peptide acts like a morphogen which alters stem cell character in the epidermis of growing leaves and blocks the formation of stomata at elevated CO2,» explains Engineer.

«We have shown that when FBW7 is functionally inactivated this leads to a block of degradation of the stem cell protein SOX9 which becomes more stable in the brain cancer cells,» said first author Aldwin Suryo Rahmanto at the department of Cell and Molecular Biolcell protein SOX9 which becomes more stable in the brain cancer cells,» said first author Aldwin Suryo Rahmanto at the department of Cell and Molecular BiolCell and Molecular Biology.

Importantly, an inhibitor of the dipeptide uptake blocks CML stem cell activity in mice.

Loss of either GSTO1 or RYR1, the researchers report, decreased the number of cancer stem cells in the primary tumor, blocked metastasis of cancer cells from the primary tumor to the lungs, decreased the duration of chemotherapy required to induce remission and increased the duration of time after chemotherapy was stopped that the mice remained tumor - free.

Novitch's UCLA lab group has likewise used its brain organoids to pinpoint additional receptors by which the virus may gain entry into neural stem cells, and identified a few other drug leads for blocking infection.

This is a fascinating new field of thought in breast cancer research, especially given the team's findings that we might be able to stop cancer stem cells by blocking the molecule FAK.»

In further work, a drug that blocks FAK reduced the formation of mammospheres, or clumps of breast cancer stem cells, showing FAK is important in cancer stem cell activity.

«We have shown that blocking the activity of FAK not only reduces the growth of breast cancer stem cells, but also improves sensitivity to radiotherapy.

To maintain its stem cells, the organism generates the signals that block differentiation inside special stem cell niches.

«3 - D printed «building blocks» of life: Scientists have developed a 3 - D printing method capable of producing highly uniform «blocks» of embryonic stem cells.»

The researchers confirmed Olig2's role in promoting motor neuron formation by increasing or blocking the function of Olig2 in the spinal cords of developing mouse and chicken embryos, as well as during motor neuron formation in mouse embryonic stem cells.

Scientists have developed a 3 - D printing method capable of producing highly uniform «blocks» of embryonic stem cells.

Reserve stem cells exposed to leucine proliferated, while those exposed to rapamycin were blocked.

A federal appeals court on Tuesday granted a «stay» that allows human embryonic stem cell (hESC) research to continue during an appeal of a 23 August district court preliminary injunction blocking it.

Lengner cautions, however, that rapamycin can not be used as a stand - in for calorie restriction, as it would linger and continue to block mTOR activation even following injury, hindering the ability of the reserve stem cells to spring into action and regenerate intestinal tissue.

In donors, blocking the interaction between Del - 1 and hematopoetic stem cells could enhance the mobilization of those progenitors into the bloodstream.

Furthermore, they suggest that blocking these inflammatory loops may be a means of targeting cancer stem cells, improving patient outcome,» he says.

In myotonic dystrophy and other related neurological disorders, the symptoms stem from repeated individual nucleotides, or «building blocks,» in the RNA in muscle tissue cells that can build up over time.

«By activating TLR3, the Zika virus blocks genes that tell stem cells to develop into the various parts of the brain.

A U.S. appeals court today upheld the legality of federally funded research on human embryonic stem cells (hESCs)-- the latest in a string of wins for the National Institutes of Health (NIH) in a 3 - year legal battle with groups that for moral reasons want to block the use of these cells.

Now, a collaboration between the RIKEN Center for Integrative Medical Science (IMS) and other institutions in Japan and Europe have found that in immune cells, simply blocking a transcription factor that leads to differentiation is sufficient to keep cells in a multipotent stem cell - like state where they can continue to proliferate and can later differentiate into various cell types.

Biologically, stem cells» future is almost completely open; politically, they may be blocked.

Some stem cell advocates worry that the move could signal the Bush Administration's intention to block NIH funding for the work.

The researchers found that when they blocked CRIPTO, the cells mostly formed differentiated cells instead of new stem cells.

«Amazingly, when the ribosomal mutant mice and the Pten mutant mice were bred together, stem cell function returned to normal, and we greatly delayed, and in some instances entirely blocked, the development of leukemia,» Dr. Morrison said.

In another set of experiments using the fly and human stem cells, the scientists added antisense oligonucleotides, bits of RNA designed to bind to the repetitive RNA strands, blocking them from interacting with the RanGAP protein.

Their surprising discovery demonstrates that the vitamin A derivative ATRA (all - trans retinoic acid), a treatment for APL that is considered to be the first example of modern targeted cancer therapy, can block multiple cancer - driving pathways and, at the same time, eliminate cancer stem cells by degrading the Pin1 enzyme.

Next, because KLF4 is involved in self - renewal of stem cell, we also examined the effect of both miR - 7 and KLF4 on proliferation of CSCs by MTS assay and found that miR - 7 was capable of blocking the growth of CSCs, whereas ectopic expression of KLF4 significantly mitigated this effect of miR - 7 (Fig. 4C).

This leads to a block of degradation of the stem cell protein SOX9 and gives rise to tumors that spread more easily -LSB-...]

Niclosamide, an old antihelminthic agent, demonstrates antitumor activity by blocking multiple signaling pathways of cancer stem cells.

Watching what cells do inside the bone is tricky: Blood - producing stem cells are rare, and bones block many of the tools that scientists would use to spy on the cells.

Embryonic stem cells — the subject of so much controversy (witness the new ruling blocking their use)-- were first cultured in the lab a little more than a decade ago; in 2006, there was another breakthrough when adult cells were coaxed into becoming induced pluripotent stem cells.

The ISSCR joins organizations and individuals around the world in celebrating the cells that are the building blocks of life: stem cells.

Researchers from the Buck Institute report one of the first demonstrations of long - term vision restoration in blind mice by transplanting photoreceptors derived from human stem cells and blocking the immune response that causes transplanted cells to be rejected by the recipient.

Preliminary studies have shown that AML stem cells produce higher levels of CD47 than normal healthy cells, and that treatment with antibodies to block CD47 allows the immune system to destroy AML cells without harming healthy cells.

After extracting tissue and isolating the stem cells, the researchers exposed the cells to Wnt3a — a human protein that switches on insulin production — and also to an antibody that blocks a natural inhibitor of insulin production.