Found that muscle - specific histone methyltransferases and microRNAs regulate the activity of Hand2, a transcription factor essential for ventricle formation and more recently showed that microRNAs can efficiently guide
stem cell fate decisions.
Particularly, he is interested in the analysis of
stem cell fate decisions and of individual stem cell clone dynamics.
Discussion themes included: - stem cell heterogeneity -
stem cell fate decisions - stem cells in regeneration & development - stem cells in disease & treatment - stem cell related bioengineering & biomaterial - theoretical stem cell biology - mathematical modelling with a focus (but no restriction) on neural stem cells, hematopoietic stem cells and diabetes.
Her group is particularly interested in the cellular and molecular mechanisms which control lung epithelial
stem cell fate decisions.
Not exact matches
Another view is that tumors can become resistant to therapy by a process called
cell fate decision, by which some tumor
cells are killed by therapy and others become cancer
stem cells.
The Hippo pathway not only defines final tissue size by controlling developmental growth, but is also key to specifying
stem cell identity and proliferation, to regeneration and tissue repair, as well as numerous
cell fate decisions.
«It suggests to us that targeting the pathways used in regulating
cell fate decisions — how
stem cells choose between
cell proliferation and differentiation — could be a more effective way of halting tumours in their tracks and lead to potential new therapies.»
He is interested in the molecular control of
stem and progenitor
cell fate decisions.
Chairs: Jozef Dulak, Jagiellonian University and Shahin Rafii, Weill Cornell Medical College Karen K. Hirschi, Yale School of Medicine Role of vascular endothelial
cells in stem cell generation and maintenance Ann Zovein, University of California, San Francisco Cell fate decisions in hemogenic endothelium (Stem Cells I under Cells and Vascular
cells in
stem cell generation and maintenance Ann Zovein, University of California, San Francisco Cell fate decisions in hemogenic endothelium (Stem Cells I under Cells and Vascular B
stem cell generation and maintenance Ann Zovein, University of California, San Francisco Cell fate decisions in hemogenic endothelium (Stem Cells I under Cells and Vascular B
cell generation and maintenance Ann Zovein, University of California, San Francisco
Cell fate decisions in hemogenic endothelium (Stem Cells I under Cells and Vascular B
Cell fate decisions in hemogenic endothelium (
Stem Cells I under Cells and Vascular B
Stem Cells I under Cells and Vascular
Cells I under
Cells and Vascular
Cells and Vascular Beds)
Lineage commitment in the mammalian embryo is most often depicted as a series of binary choices between alternate
cell states, and increasing evidence supports the hypothesis that
fate decisions in embryonic
stem (ES)
cell cultures reflect these developmental processes [1].