Sentences with phrase «stem cell genomics»

Topics covered include embryonic stem cells, pluripotency, germline stem cells, tissue - specific stem cells, stem cell differentiation, epigenetics, stem cell genomics and systems biology, genome reprogramming, cancer stem cells, stem cell niches, stem - cell - based disease models, nuclear transfer technology, bioengineering, drug discovery, in vivo imaging of stem cells, therapeutic applications, regenerative medicine, clinical and translational insights, stem cell research policies, ethical issues, and technical or resource - based innovations.

This is our dream for personalized cancer therapy, so we're not just guessing any more about which drugs will work but can choose drug targets based on what's driving that patient's cancer,» said Josh Stuart, the Baskin professor of biomolecular engineering at UC Santa Cruz, director of cancer and stem cell genomics at the UCSC Genomics Institute, and a senior corresponding author of the paper.

Not exact matches

Human Longevity has already received $ 70 million in private backing and aims to use both genomics and stem cell therapies to allow us to live longer, healthier lives.

Venter reiterated this sentiment: «Using the combined power of our core areas of expertise — genomics, informatics, and stem cell therapies, we are tackling one of the greatest medical / scientific and societal challenges — aging and aging related diseases,» he said in a statement.

His research has spanned hematopoiesis, gene therapy, stem cell biology, genomics and cancer, consistently focusing on bringing the very latest research advances to patients with heretofore incurable diseases.

«Using the combined power of our core areas of expertise — genomics, informatics, and stem cell therapies, we are tackling one of the greatest medical / scientific and societal challenges — aging and aging related diseases,» said Dr. Venter.

HLI, a privately held company headquartered in San Diego, CA was founded in 2013 by pioneers in the fields of genomics and stem cell therapy.

«The hope is that ZPF217 could be used to maintain supplies of therapeutic stem cells,» said lead study author Martin Walsh, PhD, Associate Professor of Pediatrics, Structural and Chemical Biology, and Genetics and Genomic Sciences of the Icahn School of Medicine at Mount Sinai.

Eager to sort through the pile of curriculum vitae's on his desk, Rudnicki is particularly looking for molecular geneticists working on different stem cell systems; scientists with genomics bents like proteomics, microarray analysis, and bioinformatics; and a couple of clinician scientists.

A study analyzing brain tumor genomics on a single - cell level has found evidence that cancer stem cells fuel the growth of oligodendrogliomas, a slow - growing but incurable form of brain cancer.

«Genetic engineering of human stem cells has not been used for disease - associated genomic deletions,» said Dr. Papapetrou.

In particular, the published study states that, when root stem cells die due a genomic stress, a signal of steroid hormones is sent to reservoir stem cells so that these divide and replace the damaged ones.

«A large number of quiescent hematopoietic stem cells was activated simultaneously when the epigenetic control provided by genomic imprinting was removed,» explains Venkatraman.

The results point to indirect genomic regulatory mechanisms which are important for embryonic stem cells and maintain gene expression, say Riikka Lund and Riitta Lahesmaa.

A group of researchers from the Centre for Genomic Regulation in Barcelona have discovered a faster and more efficient mechanism for reprogramming induced pluripotent stem cells (iPS).

To bypass the challenge, the team relied on their complementary expertise in genome engineering, stem cell differentiation into neurons, and genomic analysis of alternative splicing.

In the future, genomic screening at diagnosis should allow care providers to choose the best treatment option or monitor for the emergence of clone stem cells.

I don't know too many other consortia which can integrate expertise in embryonic and tissue stem cell biology, tissue regeneration and repair, bioengineering and nanotechnology, materials science, genomics and bio-informatics.

Three years ago, an I - Stem team identified a genomic anomaly that very frequently appeared in undifferentiated cell lines when the latter were forced to perform too great a number of proliferation cycles.

(B) Southern blot analysis of EcoRI - digested genomic DNA from wt, Xpd † XPCS / wt, and Xpd † XP / wt recombinant embryonic stem cell clones hybridised with the 3 ′ probe depicted in (A).

We will have major players give state of the art talks in sessions including Avian Behavior, Avian Physiology, Avian Stem Cell & Transgenesis - related Techniques, Developmental Biology, Genetic / Genomic Analysis and the Origin and Evolution of Birds, etc..

$ 1.8 M Supports Cancer Drug Discovery on Commonly Mutated Gene New Brunswick Patch — April 5, 2016 Behavioral Scientist Shares Insights about FDA's Proposed Rule on Banning Tanning Bed Use among Minors News-Medical.net - March 19, 2016 Intervention Program Reduces Caregiver Distress during Hospitalization of Pediatric Stem Cell Transplant Patients News-Medical.net - March 9, 2016 Exploring Genomic Pathways in the Development of Ovarian Cancer GMNews.com - March 2, 2016 Differences in Type of Small Protein may further Elucidate Lung Cancer Risk in African Americans ScienceDaily.com - March 2, 2016 Study Looks at Post-Treatment Resources for Prostate Cancer Patients Transitioning to Survivorship News-Medical.net - February 11, 2016 Drawing the Line on Tanning Bed Use by Teens ScienceDaily.com - December 21, 2015 What Rutgers Study Uncovered about E-Cigarette Use NJBiz.com - December 9, 2015 Identification of Barrier that Prevents Progression of Benign Kidney Tumors to Malignant Disease MedicalNewsToday.com - November, 24, 2015 What is the Color of the Lung Cancer Ribbon?

«Using the combined power of our core areas of expertise — genomics, informatics, and stem cell therapies, we are tackling one of the greatest medical / scientific and societal challenges — aging and aging related diseases,» said Dr. Venter.

Rac2 - MRC - cIII — generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors.

Dr. Reinholdt's research focuses on comparative and functional mammalian genomics, reproductive development and stem cell biology.

Dr. Conklin is the founder of several public stem cell and genomics projects including BayGenomics, GenMAPP, AltAnalyze and WikiPathways.

Dr. Conklin's expertise in the field of stem cell biology, genomics, regulatory signaling and bioinformatics is essential for the success of his research projects.

Dr. Reinholdt's research focuses on comparative and functional mammalian genomics, reproductive development and stem cell biology.Researches gamete development, which gives rise to eggs and sperm and supports early embryo development, with a focus on mammalian reproduction and fertility.

HLI, a privately held company headquartered in San Diego, CA was founded in 2013 by pioneers in the fields of genomics and stem cell therapy.

Included among the numerous recipients of Mr. Sanford's gifts, that total more than one billion dollars, are: the Edith Sanford Foundation for Breast Cancer that was created in 2012 by a gift of $ 100 million in honor of Mr. Sanford's mother who died of breast cancer when he was four years old; the Sioux Valley Hospitals and Health System, which renamed itself Sanford Health in 2007, in recognition of a $ 400 million gift; a $ 125 million gift in 2014 to establish Sanford Imagenetics, a program that will integrate genomic medicine into primary care for adults; the University of California San Diego which received a $ 100 million gift for the creation of the Sanford Stem Cell Clinical Center in 2013 to accelerate the translation of stem cell research discoveries by advancing clinical trials and patient therapies; the Burnham Institute for Medical Research that received a $ 50 million gift in 2010, and recognized its appreciation for both this and a 2008 gift of $ 20 million to the Sanford Center for Childhood Disease research at Burnham by then changing its name to Sanford Burnham Medical Research Institute; a $ 70 million gift to establish a particle physics laboratory named the Sanford Underground Research Facility; and the San Diego Consortium for Regenerative Medicine which received a gift of $ 30 million in 2008 and expressed its gratitude by renaming itself the Sanford Consortium for Regenerative MedicStem Cell Clinical Center in 2013 to accelerate the translation of stem cell research discoveries by advancing clinical trials and patient therapies; the Burnham Institute for Medical Research that received a $ 50 million gift in 2010, and recognized its appreciation for both this and a 2008 gift of $ 20 million to the Sanford Center for Childhood Disease research at Burnham by then changing its name to Sanford Burnham Medical Research Institute; a $ 70 million gift to establish a particle physics laboratory named the Sanford Underground Research Facility; and the San Diego Consortium for Regenerative Medicine which received a gift of $ 30 million in 2008 and expressed its gratitude by renaming itself the Sanford Consortium for Regenerative MedicCell Clinical Center in 2013 to accelerate the translation of stem cell research discoveries by advancing clinical trials and patient therapies; the Burnham Institute for Medical Research that received a $ 50 million gift in 2010, and recognized its appreciation for both this and a 2008 gift of $ 20 million to the Sanford Center for Childhood Disease research at Burnham by then changing its name to Sanford Burnham Medical Research Institute; a $ 70 million gift to establish a particle physics laboratory named the Sanford Underground Research Facility; and the San Diego Consortium for Regenerative Medicine which received a gift of $ 30 million in 2008 and expressed its gratitude by renaming itself the Sanford Consortium for Regenerative Medicstem cell research discoveries by advancing clinical trials and patient therapies; the Burnham Institute for Medical Research that received a $ 50 million gift in 2010, and recognized its appreciation for both this and a 2008 gift of $ 20 million to the Sanford Center for Childhood Disease research at Burnham by then changing its name to Sanford Burnham Medical Research Institute; a $ 70 million gift to establish a particle physics laboratory named the Sanford Underground Research Facility; and the San Diego Consortium for Regenerative Medicine which received a gift of $ 30 million in 2008 and expressed its gratitude by renaming itself the Sanford Consortium for Regenerative Mediccell research discoveries by advancing clinical trials and patient therapies; the Burnham Institute for Medical Research that received a $ 50 million gift in 2010, and recognized its appreciation for both this and a 2008 gift of $ 20 million to the Sanford Center for Childhood Disease research at Burnham by then changing its name to Sanford Burnham Medical Research Institute; a $ 70 million gift to establish a particle physics laboratory named the Sanford Underground Research Facility; and the San Diego Consortium for Regenerative Medicine which received a gift of $ 30 million in 2008 and expressed its gratitude by renaming itself the Sanford Consortium for Regenerative Medicine.

In a study being published online today in the journal Cell, researchers in the laboratory of Gladstone Senior Investigator Benoit Bruneau, PhD, employed stem cell technology, next - generation DNA sequencing and computing tools to piece together the instruction manual, or «genomic blueprint» for how a heart becomes a heCell, researchers in the laboratory of Gladstone Senior Investigator Benoit Bruneau, PhD, employed stem cell technology, next - generation DNA sequencing and computing tools to piece together the instruction manual, or «genomic blueprint» for how a heart becomes a hecell technology, next - generation DNA sequencing and computing tools to piece together the instruction manual, or «genomic blueprint» for how a heart becomes a heart.

Reference: September 13, 2007 issue of Cell Stem Cell under the title «Whole - Genome Mapping of Histone H3Lys4 and 27 Trimethylations Reveals Distinct Genomic Compartments in Human Embryonic Stem Cells».

Team Identifies Genetic Abnormalities in Stem Cell Lines — The study, from the Loring lab, suggests the need for frequent genomic monitoring of stem cells to assure their stability and clinical safStem Cell Lines — The study, from the Loring lab, suggests the need for frequent genomic monitoring of stem cells to assure their stability and clinical safstem cells to assure their stability and clinical safety.

With key strengths in advanced medical imaging, cell biology, genomics, immunology and stem cell biology, our scientists and their skilled staff conduct research on some of the most debilitating diseases of our time: heart disease and stroke, Alzheimer's, cancer, organ failure, diabetes and many others.

«Martin Pera brings an unparalleled depth of expertise in embryonic and pluripotent stem cell biology to our faculty, complementing and broadening our emerging research emphasis on human genomic medicine,» said Edison Liu, M.D., president and CEO of The Jackson Laboratory.

• Key strengths in advanced medical imaging, cellular and molecular biology, genomics, immunology and stem cell biology.

Once a disease has been explored with genomic, proteomic and cell biology tools, relevant targets are identified by I - Stem research teams.

I finished my postdoctoral training in cancer stem cell and genomics at the University of Texas MD Anderson Cancer Center and decided to move to the Bay Area for personal reasons.

From the NYT: «A team at the Broad Institute, a Harvard - M.I.T. collaborative for genomics research, has devised a way of screening for drugs that attack cancer stem cells but leave ordinary cells unharmed.

Exonuclease 1 is essential for maintaining genomic stability and the proliferative capacity of neural but not hematopoietic stem cells.

His clinical expertise is in cancer genomics, precision medicine and stem cell transplantation.

«A team at the Broad Institute, a Harvard - M.I.T. collaborative for genomics research, has devised a way of screening for drugs that attack cancer stem cells but leave ordinary cells unharmed.

«The greatest promise of improving the human condition is in stem cell research and genomics,» says Broad.

This provides crosslinks to external resources such as NCBI Entrez, Ensembl, iHOP, Pubgene, MEM - Multi Experiment Matrix, and a number of genomics and stem cell databases.

The center brings together leading experts in the diverse fields of neurobiology, stem cell biology, protein homeostasis, proteomics, functional genomics, and clinical neuropathology.

Dr. Pillai comes from multidisciplinary research background including molecular biology, biochemistry, stem cell biology and genomics.

Although many posit that tumor cell heterogeneity is of a genetic basis associated with inherent high genomic instability in tumor cells, the heterogeneous cellular composition in tumors has also been hypothesized, early on, to be the consequence of abnormal tumor stem cell differentiation (9).

Up to 40 investigators will eventually be part of this new program, including teams looking at experimental therapeutics, cancer stem cells, molecular imaging and genomics.

In addition, there are cross-links to annotate and characterize these genes in the context of other relevant genomic and stem cell resources.

Our lab is performing both basic and translational cancer research in the fields of endocytosis, stem cells and functional genomics.