Sentences with phrase «stem cell line with»

For more on human embryonic stem cells, see Teisha Rowland's «All Things Stem Cell post on «Induced Pluripotent Stem Cells: A New Stem Cell Line with a Long History,» The National Institute of Health's Stem Cell FAQs, or, for a visual explanation of terms used, see All Things Stem Cell's Visual Stem Cell Glossary.
A new stem cell line with the mutation for fragile X syndrome may help uncover the mechanism behind the debilitating disorder
Last week, Hwang filed a complaint with the Seoul prosecutor's office claiming that someone had switched his stem cell lines with ones from MizMedi.
Isolation of amniotic stem cell lines with potential for therapy.
In this study, published in Stem Cell Reports, the researchers used both murine and human pluripotent stem cell lines with airway secretory lineage reporters, which enables their tracking, purification and profiling.

Not exact matches

One way to enhance eggs, developed by the company OvaScience, involves supplementing an egg with mitochondria taken from stem cells found in the lining of a woman's uterus.
In all likelihood, soon after he is sworn in, federal dollars will start flowing toward research on new embryonic stem - cell lines, bringing with it new battles to fight.
Not surprisingly, President Obama received high marks from the journal, largely because his response to the question of whether he would lift Bush's ban on the federal funding of new embryonic stem - cell lines is in line with the view of most in the scientific community.
Advocates of embryonic stem cell research were thought to be in a long line of pioneers fighting the restraints of religious doctrine to push forward with scientific research.
He was referring to Intelligent Nutrients, his line of health and beauty products that meets strict NOP organic standards and focuses on sourcing ingredients in a way that supports the earth, while pushing the envelope with stem - cell science to produce maximum - efficacy products.
About three - fourths of the stem cell lines were found to be unsuitable for research, and many if not all the lines were contaminated with mouse feeder cells.
Studying mice with injuries to the lining of the stomach, the researchers blocked the animals» ability to call on stem cells for help in the stomach.
Collins and others argue not just for a permanent removal of the injunction to resume research with confidence, but also for an extension of the number of embryonic stem cell lines available to federally funded researchers.
The team produced 11 stem cell lines from 11 men, women, and children with conditions such as diabetes, spinal cord injury, and inherited immune deficiency.
«We can work with any embryonic stem cell line from any source and are not restricted to working with the very small number of federally approved lines as is the case for researchers in the United States,» says Minger.
In one promising approach, cellular reprogramming, stem cells can be generated by fusing adult skin cells with embryonic stem cells from existing cell lines.
In May 2005, Hwang and his colleagues reported that it had produced 11 new human embryonic stem (ES) cell lines that carried the genetic signature of patients with diabetes, spinal cord injury, or a genetic blood disorder (Science, 20 May, p. 1096).
Furthermore, they have found that neural stems cells can be culled from the patient's bone marrow, thus circumventing ethical and political obstacles to neural stem cell therapy as well as problems with immune rejection that sometimes arise when researchers must employ embryonic stem cell lines.
While American stem cell researchers were celebrating the final NIH stem cell guidelines, questions remain, particularly whether the National Institutes of Health will approve existing lines in time for use with stimulus funds.
While he has been working with federally - approved human ES lines, he notes that those lines could be considered illegal until they get vetted by the stem cell working group NIH plans to create.
Still it is a significant improvement over former President George W. Bush's rules that allowed federal support for work with only 21 stem cell lines already created from surplus embryos at fertility clinics.
On the other hand, the problem is, you know, with embryonic stem cells, they haven't been able to get stem cell lines from livestock animals that can proliferate in that way, without just sort of veering up in their own direction and turning into, instead of muscle, turning into brain tissue or bone tissue or something else.
The biggest question seems to be whether NIH can approve lines fast enough that they can be used with stem cell grants submitted to NIH for the money allocated under the U.S. economic stimulus plan.
The final guidelines on research with human embryonic stem cells issued on Monday by the National Institutes of Health set out criteria for determining which ES cell lines can be used in federally funded experiments and give NIH discretion to approve old lines that don't meet stringent modern ethical requirements.
The bill was put forth to loosen the restrictions Bush placed on human embryonic stem cell research on August 9, 2001, when he banned federal funding for work with any stem cell line created after that date.
Researchers remove these mechanically and, with some luck, can nurture them into an embryonic stem cell line that lives in perpetuity in the laboratory.
Badylak says his stem cell stimulator is currently being applied, with great success, to heal injured hearts, thoracic wounds, and the outer lining of the brain.
One of the most popular models is the immunodeficient nonobese diabetic severe combined immunodeficiency (NOD scid) gamma (NSG) transgenic mouse line, which can be endowed with a humanized immune system using CD34 + hematopoietic stem cells.
In a statement put on the Web this morning, NIH reported that all 64 lines «show characteristics of stem cell morphology» and have undergone several population doublings, and most of them have demonstrated all the protein markers «known to be associated with human embryonic stem cells
If there was one embryonic stem cell, and it differentiated into five distinct specialized cells, and then these specialized cells were reprogrammed into five distinct induced stem cell sets — then at least one of these lines would be similar to an embryonic cell with 95 % confidence.
Hajishengallis, Chavakis and their colleagues identified the protein on hematopoetic stem cells with which Del - 1 interacts, the ß3 integrin, perhaps pointing to a target for therapeutic interventions down the line.
The nose is lined with sensory tissue, the olfactory epithelium, that contains various types of cells, all of which arise from olfactory stem cells (green).
His group began with 242 eggs, but after removing the eggs» nuclei and swapping in those of somatic cells, the investigators produced only 30 blastocysts (week - old embryos), from which they coaxed just one stem cell line into being.
The university recruited him with one of the first awards for established investigators from the Cancer Prevention and Research Institute of Texas (CPRIT), a $ 3 billion, 10 - year cancer research fund along the lines of California's stem cell initiative.
In people with SCID, the stem cells that would become T cells — one of the immune system's main lines of defense against infection — lack a crucial protein receptor that tells them to start reproducing.
Later, during a chance discussion with European colleagues, stem cell researcher George Daley of Children's Hospital Boston and the Harvard Stem Cell Institute learned that they had received samples of the cell line before the work was retracstem cell researcher George Daley of Children's Hospital Boston and the Harvard Stem Cell Institute learned that they had received samples of the cell line before the work was retraccell researcher George Daley of Children's Hospital Boston and the Harvard Stem Cell Institute learned that they had received samples of the cell line before the work was retracStem Cell Institute learned that they had received samples of the cell line before the work was retracCell Institute learned that they had received samples of the cell line before the work was retraccell line before the work was retracted.
Attempting to find middle ground in the contentious debate over human embryonic stem cells, President George W. Bush announced 9 August that the National Institutes of Health (NIH) will be allowed to fund work with embryonic stem (ES) cell lines — but only those lines that have already been derived.
Last week the National Institutes of Health (NIH) cancelled its planned meeting of the panel that is supposed to determine whether a given stem cell line was derived in accordance with NIH's ethical guidelines (ScienceNOW, 3 April).
With so much work needed in studying the nature of stem cells and using them to study disease processes, therapies based on ES cells seem very far down the line, noted Lorenz Studer of Memorial Sloan - Kettering Cancer Center in New York, who pointed out that so far there have only been two published papers on therapeutic cloning, both of them in mice.
The vessels are lined with endothelial cells, which secrete chemical signals that help stem cell survive.
Pediatric stem cell transplant and cancer patients often are discharged from the hospital with an external central venous line for medications that parents or other caregivers must clean and flush daily to avoid potentially life - threatening infections.
They tested 120 neural stem cell lines in the lab for stability and robustness and in animals for the capacity to engraft with minimal immune rejection.
A Phase 3 Open - Label Randomized Study of Quizartinib (AC220) Monotherapy Versus Salvage Chemotherapy in Subjects with FLT3 - ITD Positive Acute Myeloid Leukemia (AML) Refractory To or Relapsed After First - line Treatment With or Without Hematopoietic Stem Cell Transplantation (HSCT) Consolidawith FLT3 - ITD Positive Acute Myeloid Leukemia (AML) Refractory To or Relapsed After First - line Treatment With or Without Hematopoietic Stem Cell Transplantation (HSCT) ConsolidaWith or Without Hematopoietic Stem Cell Transplantation (HSCT) Consolidation
This makes a certain kind of sense, since the stem cells in the paternal germ line undergo continuous cell division throughout a man's life, whereas a woman is born with all of the eggs she'll ever have.
• Subject is refractory to or relapsed after first - line AML therapy (with or without hematopoietic stem cell transplant (HSCT)-RRB-.
The goal of this protocol (written in French) is to describe the steps and quality controls to prepare new stable murine embryonic stem cells lines: ① either from wild type mouse embryos to introduce a mutation by genetic targeting or homologous recombination to get a genetically modified mouse line ② or from genetically modified mouse embryos with two aims:
Establishment of a human embryonic germ cell line and comparison with mouse and human embryonic stem cells.
Establishment of an induced pluripotent stem cell (iPSC) line from a patient with Clozapine - responder Schizophrenia.
To do so, they started with a human embryonic stem cell line, which they chemically nudged to become cells that form what's known as the primitive streak on the hollow ball of cells of the early embryo.
NeuroStemcell is focused on the identification and systematic comparison of progenitor cell lines with the most favourable characteristics for mesDA and striatal GABAergic neuronal differentiation, generated either directly from human embryonic stem (ES) cells, from Neural Stem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals modstem (ES) cells, from Neural Stem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals modStem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals modStem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals models.
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