Finally, he opened the door to funding research involving
stem cell lines created by producing human embryos by somatic cell nuclear transfer or other means specifically for research in which they are killed.
The bill was put forth to loosen the restrictions Bush placed on human embryonic stem cell research on August 9, 2001, when he banned federal funding for work with
any stem cell line created after that date.
Not exact matches
Although he never banned this research outright, President Bush limited federal funding for research to the embryonic
stem cell lines that existed before August 2001, thus drawing a
line at destroying human embryos
created after that date.
That includes not only procedures in which embryonic -
stem -
cell lines are
created, but also those that use previously derived
cell lines.
To solve this, West proposed «therapeutic cloning» — taking the nucleus out of a patient's
cell, transferring it into an egg
cell to
create a cloned embryo, then using that embryo to derive patient - matched
stem -
cell lines.
In September Harvard University scientists reported using existing
stem cell lines — not eggs — to
create more
stem cells.
Hamilton announced the newest organ - on - chip innovation, which recreates an intestinal
lining using patient - derived
stem cells,
created through a partnership between Emulate and Cedars - Sinai Board of Governors Regenerative Medicine Institute.
Ongoing attempts to
create human
stem cell lines using SCNT have yet to achieve success.
Since 2004, several groups have reported
creating stem cell lines through parthenogenesis.
McCain would ban scientists from using donor eggs to
create disease - specific
stem cell lines or chimeric animals to see how human
stem cells behave during development.
While he has been working with federally - approved human ES
lines, he notes that those
lines could be considered illegal until they get vetted by the
stem cell working group NIH plans to
create.
Still it is a significant improvement over former President George W. Bush's rules that allowed federal support for work with only 21
stem cell lines already
created from surplus embryos at fertility clinics.
And so, you know, again theoretically, you could take one
stem cell line and
create tens of thousands of tons of food.
«The beautiful thing,» Lanza says, «is that if you have an embryonic
stem cell line that is O negative, because it's immortal you could
create an unlimited amount of universal blood that would match virtually everybody, so you wouldn't have to worry about matching blood types.»
If the president's philosophy — to restrict federal funding to research on
cell lines created prior to August 9, 2001 — lacks a principled moral basis that amplifies the view that the governmental obstacles imposed on
stem cell research, and the delays they have caused, themselves represent an ethical problem.
Last January, the House of Representatives voted, 253 to 174, to pass a bill, H.R. 3, that would allow researchers to use leftover embryos from in vitro fertilization (IVF) clinics to
create new
lines of embryonic
stem cells, and in April, the Senate passed its version of the bill.
In the face of these setbacks, many scientists have focused on new methods of
creating stem cell lines without destroying embryos.
Mindful of public sensitivities, Daley opted to pursue experiments using what he considers the least controversial human materials to
create new nonpresidential
stem cell lines — poor quality embryos and oocytes that, in his words, «otherwise would have been disposed of as medical waste.»
In May 2006, Eggan's lab received approval from Harvard to seek healthy human eggs from female donors, a first step toward using research cloning to
create new
stem cell lines.
These human
cells were ineligible for federal research funds because they had been
created after President Bush's August 9, 2001, announcement freezing the number of government - approved
stem cell lines.
By May 2005 they had used cloning techniques to
create 11
stem cell lines, each one the perfect genetic match of a different patient, another first.
For now, the new
stem cell lines UC Berkeley researchers have
created will help scientists understand the first molecular decisions made in the early embryo.
According to a new analysis, the
cell line they
created represented the first example of parthenogenetic human embryonic
stem (ES)
cells.
Though Hwang Woo - suk, a South Korean scientist claimed to have
created the first human embryonic clone and derived a
stem -
cell line from it in 2004 his work was later shown to be fraudulent.
During the next five years, KOMP2 will transform the knockout mouse embryonic
stem (ES)
cells into adult mice for 2,500
lines of well - characterized knockout mice strains, and IMPC will
create about 2,500 additional knockout mouse strains.
June 21, 2007: Bush vetoes another DeGette - sponsored bill that would allow research on all
stem -
cell lines using
cells created for in - vitro fertilization and scheduled to be discarded.
KOMP2 and IMPC researchers will begin by
creating lines of knockout mice from embryonic
stem cells produced by KOMP.
What Collins does not say, however, is that the new NIH guidelines also allow for federal funds to be used in studying new human embryonic
stem cell lines that are
created (by private entities, of course) beyond the 700 currently in existence.
The new NIH guidelines do not permit the use of federal funds for
creating new human embryonic
stem cell lines.
In partnership with several international programs, the initial five - year phase of KOMP will reach its goal of
creating knockout mouse embryonic
stem cell lines for each of the approximately 21,000 protein - coding genes in the mouse genome this year.
Reprogramming adult
cells to function like embryonic
stem cells is one way researchers hope to
create patient - specific
cell lines to regenerate tissue or to study specific diseases in the laboratory.
The team that generated the insulin - producing embryonic
stem cell line, e.g., had a success rate of under six percent, using 71 eggs to produce four
stem cell lines from the embryos they
created and destroyed.
One of those teams
created a cloned embryo from the somatic
cells of a diabetic patient; this embryo was then destroyed in order to generate an insulin - producing embryonic
stem cell line.
The use of higher resolution techniques, such as array CGH and, soon, whole genome sequencing, will enhance the ability of researchers to examine
stem cell lines to determine which are best — least likely to result in diseases and other problems — to use in
creating therapies for use in humans.
He claimed that the rules violated the Dickey - Wicker amendment because embryos must be destroyed in the process of
creating embryonic
stem cell lines.
On March 9, 2009, President Obama lifted the ban that had previously restricted the use of federal funds for embryonic
stem cell research on
cell lines that had been
created after August 9, 2001.
Stice's neural
cell kits
created from human embryonic
stem cell lines last up to six months.
He could have left the funding of research involving
cell lines created by the destruction of human embryos in place, and led the charge to promote ethically unproblematic non-embryo-destructive forms of
stem cell science.
The legislation would lift Bush's restriction that limits federal research on embryonic
stem -
cell lines to those
created before August 2001.
In essence, the signers were trying to get the President to change his mind about
stem cell lines used for research so that Congress does not have to
create a legislative solution.
Here we used genome - saturated mutagenesis to
create a biobank of over 100,000 individual haploid mouse embryonic
stem (mES)
cell lines targeting 16,970 genes with genetically barcoded, conditional and reversible mutations.
Cells from these embryos can be used to
create pluripotent
stem cell «
lines» —
cell cultures that can be grown indefinitely in the laboratory.
In addition, three California - based ALS research labs have joined forces to form the Neuro Collaborative, which will
create induced pluripotent
stem (iPS)
cell lines from ALS patients that can be used to screen for new drugs and will be shared with the other groups.