Sentences with phrase «stem cell lines derived»

WARF distributes stem cell lines derived by James Thompson, a researcher at the University of Wisconsin, Madison.

Neural stem cell lines derived from human fetal brain tissue achieved the same feats, the researchers report in the October issue of Nature Neuroscience.

A White House spokesperson said last night that stem cell lines derived after 9 August 2001 will not be eligible for NIH funding.

He ruled that work on existing embryonic stem cell lines derived outside federally funded labs did not violate a ban on the destruction of embryos.

In February 2004 Hwang and his research group reported the first embryonic stem cell line derived from a cloned human embryo.

ScienceDaily «A human stem cell line derived from embryos that were identified by preimplantation genetic diagnosis (PGD) to carry the mutation for fragile X syndrome has...

Not exact matches

That includes not only procedures in which embryonic - stem - cell lines are created, but also those that use previously derived cell lines.

To solve this, West proposed «therapeutic cloning» — taking the nucleus out of a patient's cell, transferring it into an egg cell to create a cloned embryo, then using that embryo to derive patient - matched stem - cell lines.

In addition, where cells derived from embryonic stem cells are great at proliferating — a potentially critical feature if one wants to grow sufficient numbers of cells for clinical use — ones from the iPS lines were much feebler.

Another problem is that in its July 2009 Guidelines on Human Stem Cell Research, NIH spelled out specific requirements about embryo donation for newly derived lines, says Pilar Ossorio, a legal scholar who studies research ethics at the University of Wisconsin Law School.

Hamilton announced the newest organ - on - chip innovation, which recreates an intestinal lining using patient - derived stem cells, created through a partnership between Emulate and Cedars - Sinai Board of Governors Regenerative Medicine Institute.

In an advance touted as a way around current political logjams, scientists have said they can derive human embryonic stem (ES) cell lines without destroying an embryo.

Researchers working to understand how to manipulate this powerful tool get their supply from stem cell lines, groups of stem cells derived from animal or human tissue that can reproduce themselves indefinitely.

In 2008 a group of medical researchers led by Robert Lanza at Advanced Cell Technology in Worcester, Massachusetts, reported another leap: They discovered a way to avoid destroying the embryo by deriving an entire stem cell line from a single embryonic cCell Technology in Worcester, Massachusetts, reported another leap: They discovered a way to avoid destroying the embryo by deriving an entire stem cell line from a single embryonic ccell line from a single embryonic cellcell.

«Basically it comes [down] to how many eggs you would need to derive one embryonic stem cell line.»

Two weeks later, the researchers found the brain - derived cells in the regenerating muscle tissue — suggesting that neural stem cell lines might be candidates for treating certain muscle diseases.

Using cutting edge «disease in a dish» technologies, the researchers are now following up the leads discovered in blood cell lines in neurons induced from stem cells derived from the blood of PMDD patients — in hopes of gaining a more direct window into the ESC / E (Z) complex's role in the brain.

Attempting to find middle ground in the contentious debate over human embryonic stem cells, President George W. Bush announced 9 August that the National Institutes of Health (NIH) will be allowed to fund work with embryonic stem (ES) cell lines — but only those lines that have already been derived.

Last week the National Institutes of Health (NIH) cancelled its planned meeting of the panel that is supposed to determine whether a given stem cell line was derived in accordance with NIH's ethical guidelines (ScienceNOW, 3 April).

Cibelli and Daley both say that parthenote - derived cell lines could have an important place in stem cell research.

In the original agreement, WARF gave Geron exclusive rights to develop diagnostic and treatment products in six types of stem cell - derived cell lines: pancreatic, heart muscle, nerve, blood, bone, and liver.

«The use of nonhuman oocytes for SCNT is currently the only ethically justifiable option given the large numbers of eggs required to derive cloned human stem cell lines,» he said.

Though Hwang Woo - suk, a South Korean scientist claimed to have created the first human embryonic clone and derived a stem - cell line from it in 2004 his work was later shown to be fraudulent.

Twenty - seven human embryonic stem cell (hESC) lines are ethically derived and should be approved for use in research funded by the US linkurl: National Institutes of Health; http://www.nih.gov/ (NIH), a committee advising the NIH director linkurl: recommended today (December 4).

His executive order allowed funding on embryonic stem - cell lines derived from embryos that had already been destroyed, but excluded funding of research using stem cells from embryos destroyed after August 9, 2001 (the date of his announced policy).

Only a few laboratories in the world are attempting this technique in human stem cell research and, thus far, no human stem cell lines have been derived using this method.

In effect, the new guidelines provide an incentive to private research entities to obtain so - called «leftover» embryos from fertility clinics and derive stem cell lines from them in order to obtain NIH research dollars to study the derived lines.

NeuroStemcell is focused on the identification and systematic comparison of progenitor cell lines with the most favourable characteristics for mesDA and striatal GABAergic neuronal differentiation, generated either directly from human embryonic stem (ES) cells, from Neural Stem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals modstem (ES) cells, from Neural Stem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals modStem (NS) cells derived from ES cells or fetal brain, from induced Pluripotent Stem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals modStem (iPS) cells or from in vitro short - term expanded neural progenitors from ventral midbrain grown as neurospheres (VMN, Ventral Midbrain Neurospheres) 4, and perform rigorous and systematic testing of the most prominent candidate cells in appropriate animals models.

«Finally, to assess the potential fate of mtDNA under condition when the cells can replicate extensively (longer than allowed by UK law), they derived human embryonic stem cell (hESC) lines from five ePNT blastocysts.

Using pre-implantation genetic diagnosis derived human embryonic stem cell lines (hES) or human induced pluripotent stem cells carrying the causal mutation for neuro - muscular diseases, our objective is double: identify new physiopathogical mechanisms and develop new therapeutic strategies.

Further phenotypic characterization revealed that LKB1 is required for the differentiation and maintenance of two NCC - derivatives, Schwann cells and the ENS. Using a model of neural crest stem cell line, we demonstrated that Lkb1 is key for neural crest - derived glial commitment.

Eliminating these constraints, hepatocytes differentiated from human induced pluripotent stem (hiPS) cells provide an unlimited supply of functional hepatocytes from each parental cell line, which can be derived noninvasively from a diseased or healthy person.

When the studies of mitochondrial carryover were done in embryonic stem cells derived from ePNT blastocysts (to allow for more cell divisions during which instability could manifest), some stem cell lines displayed instability and an increase in mitochondrial DNA carryover with time.

The AST - OPC1 stem cell lines were derived from an embryo that was originally meant for an in vitro fertilization procedure in the late 1990's.

Such an immunological exemption could alleviate many concerns about using cells for therapy that don't exactly match the recipient's immune system - such as existing embryonic stem cell lines that are not directly derived from the recipient.

The majority of gene - targeting experiments in mice are performed in 129Sv - derived embryonic stem (ES) cell lines, which are generally considered to be more reliable at colonizing the germ line than ES cells derived from other strains.

Labs that derive new human embryonic stem cell lines are few, partly because they can not get financial support from federal sources.

Also, pESC lines, that carry isogenic genome information from the oocyte donors, can be derived and may represent a potential alternative source of stem cells for basic scientific studies as well as novel therapeutic application.

Obama called upon the National Institutes of Health to set up rigorous guidelines to ensure that new stem cells lines were derived by ethical practices.

The UC06 (HSF6) human ES cell line (P62) was obtained from the National Stem Cell Bank (NSCB), and the adipose derived mesenchymal stem cell (AD - MSC) line was generously obtained from Dr. Jeffrey Gimble from the Penington Biomedical Research Institcell line (P62) was obtained from the National Stem Cell Bank (NSCB), and the adipose derived mesenchymal stem cell (AD - MSC) line was generously obtained from Dr. Jeffrey Gimble from the Penington Biomedical Research InstitStem Cell Bank (NSCB), and the adipose derived mesenchymal stem cell (AD - MSC) line was generously obtained from Dr. Jeffrey Gimble from the Penington Biomedical Research InstitCell Bank (NSCB), and the adipose derived mesenchymal stem cell (AD - MSC) line was generously obtained from Dr. Jeffrey Gimble from the Penington Biomedical Research Institstem cell (AD - MSC) line was generously obtained from Dr. Jeffrey Gimble from the Penington Biomedical Research Institcell (AD - MSC) line was generously obtained from Dr. Jeffrey Gimble from the Penington Biomedical Research Institute.

«Over a thousand lines have been derived since August 9, 2001, many with attributes beneficial to medical research,» says Daley, whose own lab has derived 18 new stem cell lines.

Thus, all research on lines of human embryonic stem cells as the cells of various phenotypes derived from these lines should aim to lexploration mechanisms or the development and validation of therapeutic applicable to serious diseases.

On August 23, 2010, Judge Royce Lamberth of the United States District Court for the District of Columbia issued a preliminary injunction against the National Institutes of Health (NIH) guidelines allowing federal dollars to fund projects in which embryos were destroyed to derive new stem cell lines.

Embryonic stem (ES) cells are karyotypically normal, embryo - derived cell lines that are pluripotent, i.e. capable of generating all the cell types of the future organism, but not the extra-embryonic lineages.

In this way embryo - derived stem cell lines and ES cell differentiation may be providing access to potential «transition states,» required for lineage specification in vivo.

However, some consider human embryonic stem cell research controversial because, in some cases, the new stem cell lines are derived frozen human embryos that have been donated for research.

The 19 hES cell lines derived in Strasbourg and banked at I - Stem are registered in the European Registry (hESCREG).

I - Stem's biobank contains a total of 38 hES cell lines covering 14 monogenic diseases: 19 were imported from foreign laboratories and 19 were derived in France (Tropel et al, 2010).

A glomerulus - on - a-chip lined by human stem cell - derived kidney cells could help model patient - specific kidney diseases and guide therapeutic discovery

Various cell types have been examined for use in RPE cell replacement including immortalized cell lines, such as the human RPE cell line, ARPE19 [2], sheets of adult RPE [3], foetal RPE [4], RPE derived from human embryonic stem cells (HESC - RPE)[5]--[10] and many non-RPE cells lines [11]--[15].