Sentences with phrase «stem cell lines from»

DBA Cord Blood Registry (CBR) are collaborating to customize the creation of high - quality stem cell lines from umbilical cord blood tissue...

Whereas the derivation of stem cell lines from human embryos is subject to specific regulation by the Human Fertilisation and Embryology Authority (HFEA), UK law does not distinguish between fetal tissue and other tissue from living patients.

The team that generated the insulin - producing embryonic stem cell line, e.g., had a success rate of under six percent, using 71 eggs to produce four stem cell lines from the embryos they created and destroyed.

In effect, the new guidelines provide an incentive to private research entities to obtain so - called «leftover» embryos from fertility clinics and derive stem cell lines from them in order to obtain NIH research dollars to study the derived lines.

Australian researchers have so far generated over 50 embryonic stem cell lines from surplus embryos, and three research groups have been licensed to attempt somatic cell nuclear transfer.

On the other hand, the problem is, you know, with embryonic stem cells, they haven't been able to get stem cell lines from livestock animals that can proliferate in that way, without just sort of veering up in their own direction and turning into, instead of muscle, turning into brain tissue or bone tissue or something else.

At the University of Washington, Hannele Ruohola - Baker, professor of biochemistry and associate director of the Institute for Stem Cell and Regenerative Medicine, Julie Mathieu, acting instructor and Henrik Sperber, graduate student, withdraw embryonic stem cell lines from liquid nitrogen storage.

Dr. Jochen Maurer and his research group were able to cultivate several cancer stem cell lines from triple receptor - negative breast cancer that are excellent representations of the original tumors they isolated from the patients.

The team produced 11 stem cell lines from 11 men, women, and children with conditions such as diabetes, spinal cord injury, and inherited immune deficiency.

In 2007, however, scientists at International Stem Cell, a California - based biotech firm, reported the first successful creation of human stem cell lines from unfertilized eggs.

Subsequent efforts have averaged one stem cell line from 16.8 embryos.

«We can work with any embryonic stem cell line from any source and are not restricted to working with the very small number of federally approved lines as is the case for researchers in the United States,» says Minger.

In 2008 a group of medical researchers led by Robert Lanza at Advanced Cell Technology in Worcester, Massachusetts, reported another leap: They discovered a way to avoid destroying the embryo by deriving an entire stem cell line from a single embryonic cell.

Paper on creation of stem cell line from human blastocyst contains fabricated data, university committee concludes

Prior to the advent of iPSCs in 2007 the only method researchers may have had to produce a genetically matched stem cell line from a patient's own cells was Somatic Cell Nuclear Transfer (SCNT), i.e., cloning.

In addition, Dr. Reinholdt's laboratory developed a novel protocol for derivation of embryonic stem cell line from a variety of strains that were previously deemed recalcitrant after years of failed attempts by the scientific community.

Not exact matches

One way to enhance eggs, developed by the company OvaScience, involves supplementing an egg with mitochondria taken from stem cells found in the lining of a woman's uterus.

Not surprisingly, President Obama received high marks from the journal, largely because his response to the question of whether he would lift Bush's ban on the federal funding of new embryonic stem - cell lines is in line with the view of most in the scientific community.

The National Institutes of Health (NIH) has allowed a contract for the dissemination of embryonic stem cell lines approved for US government funding to lapse, shuttering a key stem cell bank, and doubling the price researchers pay for samples of some human embryonic stem cell (hESC) line... from $ 500 per vial of frozen cells to $ 1,000.

As well as allowing the use of stem cells grown from established cell lines, the technology could enable the creation of improved human tissue models for drug testing and potentially even purpose - built replacement organs.

As the heart starts pumping a primitive blood - like fluid around the body of an embryo, the change in pressure from the flowing liquid is the cue for cells lining the aorta to change first into blood stem cells, then into all blood - cell types in the body.

In addition, where cells derived from embryonic stem cells are great at proliferating — a potentially critical feature if one wants to grow sufficient numbers of cells for clinical use — ones from the iPS lines were much feebler.

This is a breast cancer stem cell line 1 (BCSC1) from the newly established cell model.

He noted that even the Obama administration's 75 approved stem cell lines (increased from the Bush administration's 21) are not enough for robust research in the field.

Wayne Hellstrom of Tulane University in New Orleans, Louisiana, and colleagues, extracted stem cells from fat and placed them onto layers of tissue taken from the lining of pig intestine.

Hwang claimed his stem cells did not result from parthenogenesis, but George Daley, head of the study, showed that the genome of Hwang's cell line has a genetic signature that indicates it sprang from a parthenogenetic embryo.

In one promising approach, cellular reprogramming, stem cells can be generated by fusing adult skin cells with embryonic stem cells from existing cell lines.

To see whether cancer stem cell renewal involves a chain of events similar to that used by embryonic stem cells, and whether the process was affected by oxygen levels, Semenza and graduate student Chuanzhao Zhang focused their studies on two human breast cancer cell lines that responded to low oxygen by ramping up production of the protein ALKBH5, which removes methyl groups from mRNAs.

McCain would ban scientists from using donor eggs to create disease - specific stem cell lines or chimeric animals to see how human stem cells behave during development.

Furthermore, they have found that neural stems cells can be culled from the patient's bone marrow, thus circumventing ethical and political obstacles to neural stem cell therapy as well as problems with immune rejection that sometimes arise when researchers must employ embryonic stem cell lines.

In a paper published online yesterday in Stem Cells, the researchers report that they succeeded in generating pluripotent human ES cell lines — i.e., cells that can develop into many different kinds of cells — from one of the 13 late - arrested embCells, the researchers report that they succeeded in generating pluripotent human ES cell lines — i.e., cells that can develop into many different kinds of cells — from one of the 13 late - arrested embcells that can develop into many different kinds of cells — from one of the 13 late - arrested embcells — from one of the 13 late - arrested embryos.

«Physical forces are certainly a factor in getting the lung lining to be fully functional,» says Anne Bishop at Imperial College London, who has made alveolar cells from mouse stem cells using growth factors alone.

The researchers have isolated the sesquiterpene lactone damsin from the plant and studied its effect on cancer stem cells in three different breast cancer cell lines.

Researchers working to understand how to manipulate this powerful tool get their supply from stem cell lines, groups of stem cells derived from animal or human tissue that can reproduce themselves indefinitely.

Still it is a significant improvement over former President George W. Bush's rules that allowed federal support for work with only 21 stem cell lines already created from surplus embryos at fertility clinics.

Last January, the House of Representatives voted, 253 to 174, to pass a bill, H.R. 3, that would allow researchers to use leftover embryos from in vitro fertilization (IVF) clinics to create new lines of embryonic stem cells, and in April, the Senate passed its version of the bill.

In May 2006, Eggan's lab received approval from Harvard to seek healthy human eggs from female donors, a first step toward using research cloning to create new stem cell lines.

They used the gene editing technology CRISPR to engineer a series of human embryonic stem cell lines, which were identical apart from the number of DNA repeats that occurred at the ends of their HTT genes.

In one study, geneticist Joseph Ecker at the Salk Institute in California took various stem cell lines reprogrammed from skin, fat, and other tissues and examined each line's genome for dna methylation, chemical marks that alter how genes are expressed.

Alternative cell lines, such as induced pluripotent stem cells generated from patient skin cells, offer a more accurate window on human biology, he says.

The challenge, he says, will be figuring out how to force the transition from progenitors to stem cells, which spontaneously occurred in about one third of testicular cell lines.

Using genetic analyses, the researchers showed that a commonly used cell line which was established in Uppsala, Sweden, almost fifty years ago does not originate from the patient it is claimed to stem from.

Scientists have already reported progress in growing precursor cells for eggs and sperm from both iPS and embryonic stem cell lines.

Researchers compared induced pluripotent stem cells lines reprogrammed from different adult cell types that have been previously differentiated from embryonic stem cells.

Furthermore, stem - cell lines from mice begin to lose their ability to produce many types of cells after as few as 20 generations, and researchers assume the same will prove true for stem cells from humans.

This Korean researcher racked up a series of important advances in embryonic stem cell technology, including the first lines of cells from patients

The nose is lined with sensory tissue, the olfactory epithelium, that contains various types of cells, all of which arise from olfactory stem cells (green).

In February 2004 Hwang and his research group reported the first embryonic stem cell line derived from a cloned human embryo.

They then went on to demonstrate that the stem cell lines originated from the skin cell donors.

His group began with 242 eggs, but after removing the eggs» nuclei and swapping in those of somatic cells, the investigators produced only 30 blastocysts (week - old embryos), from which they coaxed just one stem cell line into being.