Sentences with phrase «stem cell lines using»

That bill, based on one from Rep. Diana DeGette, D - Colo., would have allowed federal dollars to flow toward research on stem cell lines using embryos left over from in vitro fertilization, slated for disposal and donated by the parents.

Others were disappointed that the White House had effectively prohibited the creation of new stem cell lines using federal funding.

Ongoing attempts to create human stem cell lines using SCNT have yet to achieve success.

In essence, the signers were trying to get the President to change his mind about stem cell lines used for research so that Congress does not have to create a legislative solution.

Not exact matches

In August of last year, President Bush approved the use of federal funds to support research on a limited number of existing human embryonic stem cell lines.

As well as allowing the use of stem cells grown from established cell lines, the technology could enable the creation of improved human tissue models for drug testing and potentially even purpose - built replacement organs.

That includes not only procedures in which embryonic - stem - cell lines are created, but also those that use previously derived cell lines.

To solve this, West proposed «therapeutic cloning» — taking the nucleus out of a patient's cell, transferring it into an egg cell to create a cloned embryo, then using that embryo to derive patient - matched stem - cell lines.

In addition, where cells derived from embryonic stem cells are great at proliferating — a potentially critical feature if one wants to grow sufficient numbers of cells for clinical use — ones from the iPS lines were much feebler.

In September Harvard University scientists reported using existing stem cell lines — not eggs — to create more stem cells.

Hamilton announced the newest organ - on - chip innovation, which recreates an intestinal lining using patient - derived stem cells, created through a partnership between Emulate and Cedars - Sinai Board of Governors Regenerative Medicine Institute.

A stem cell core facility at CHOP, directed by study co-author Deborah French under the auspices of the hospital's Center for Cellular and Molecular Therapeutics, generated the iPSCs lines used in these studies.

To see whether cancer stem cell renewal involves a chain of events similar to that used by embryonic stem cells, and whether the process was affected by oxygen levels, Semenza and graduate student Chuanzhao Zhang focused their studies on two human breast cancer cell lines that responded to low oxygen by ramping up production of the protein ALKBH5, which removes methyl groups from mRNAs.

The laboratory process, described in the journal Scientific Reports, entails genetically modifying a line of human embryonic stem cells to become fluorescent upon their differentiation to retinal ganglion cells, and then using that cell line for development of new differentiation methods and characterization of the resulting cells.

McCain would ban scientists from using donor eggs to create disease - specific stem cell lines or chimeric animals to see how human stem cells behave during development.

In its comment on the draft policy, the the International Society for Stem Cell Research asks NIH to define some «core principles» covering what is ethically acceptable rather than set explicit rules that might exclude «lines that have been in routine use for the past ten years.»

«Physical forces are certainly a factor in getting the lung lining to be fully functional,» says Anne Bishop at Imperial College London, who has made alveolar cells from mouse stem cells using growth factors alone.

During the last decade, some researchers have claimed that primordial follicles in adult mouse ovaries turn over and that females use adult germ - line stem cells to constantly resupply the follicle pool and sustain ovulation.

While American stem cell researchers were celebrating the final NIH stem cell guidelines, questions remain, particularly whether the National Institutes of Health will approve existing lines in time for use with stimulus funds.

The team used five types of antibiotics — including one used to treat acne (doxycycline)-- on cell lines of eight different types of tumour and found that four of them eradicated the cancer stem cells in every test.

The biggest question seems to be whether NIH can approve lines fast enough that they can be used with stem cell grants submitted to NIH for the money allocated under the U.S. economic stimulus plan.

Stem cell advocates have been expressing serious worry that ethical requirements spelled out in the draft guidelines — in particular, informed consent procedures for embryo donors — will rule out the use of many existing human embryonic stem cell lines, including the 21 lines approved under the Bush AdministratStem cell advocates have been expressing serious worry that ethical requirements spelled out in the draft guidelines — in particular, informed consent procedures for embryo donors — will rule out the use of many existing human embryonic stem cell lines, including the 21 lines approved under the Bush Administratstem cell lines, including the 21 lines approved under the Bush Administration.

The final guidelines on research with human embryonic stem cells issued on Monday by the National Institutes of Health set out criteria for determining which ES cell lines can be used in federally funded experiments and give NIH discretion to approve old lines that don't meet stringent modern ethical requirements.

Last January, the House of Representatives voted, 253 to 174, to pass a bill, H.R. 3, that would allow researchers to use leftover embryos from in vitro fertilization (IVF) clinics to create new lines of embryonic stem cells, and in April, the Senate passed its version of the bill.

Mindful of public sensitivities, Daley opted to pursue experiments using what he considers the least controversial human materials to create new nonpresidential stem cell lines — poor quality embryos and oocytes that, in his words, «otherwise would have been disposed of as medical waste.»

In May 2006, Eggan's lab received approval from Harvard to seek healthy human eggs from female donors, a first step toward using research cloning to create new stem cell lines.

One of the most popular models is the immunodeficient nonobese diabetic severe combined immunodeficiency (NOD scid) gamma (NSG) transgenic mouse line, which can be endowed with a humanized immune system using CD34 + hematopoietic stem cells.

They used the gene editing technology CRISPR to engineer a series of human embryonic stem cell lines, which were identical apart from the number of DNA repeats that occurred at the ends of their HTT genes.

Using this method, they tracked the tendency of the X and the Y chromosome copies to move to the daughter germ line stem cell or to the gonialblast.

Using genetic analyses, the researchers showed that a commonly used cell line which was established in Uppsala, Sweden, almost fifty years ago does not originate from the patient it is claimed to stem from.

There are many hundreds, if not thousands, of different stem cell lines in use around the world.

Many researchers are already using stem cell lines in drug development, and to further understanding of often - complex diseases.

In August of last year, President George W. Bush announced that scientists who received public research money could use only the human embryonic stem - cell lines that already exist — a decision that dismayed many researchers.

By May 2005 they had used cloning techniques to create 11 stem cell lines, each one the perfect genetic match of a different patient, another first.

The 2015 regulations state that hospitals planning to carry out stem - cell clinical work must use government - certified ES - cell lines and pass hospital - review procedures.

The only stem cell research he would permit, Bush said, was research using existing embryonic lines as well as so - called adult stem cells, which occur in anyone of any age.

Using cutting edge «disease in a dish» technologies, the researchers are now following up the leads discovered in blood cell lines in neurons induced from stem cells derived from the blood of PMDD patients — in hopes of gaining a more direct window into the ESC / E (Z) complex's role in the brain.

With so much work needed in studying the nature of stem cells and using them to study disease processes, therapies based on ES cells seem very far down the line, noted Lorenz Studer of Memorial Sloan - Kettering Cancer Center in New York, who pointed out that so far there have only been two published papers on therapeutic cloning, both of them in mice.

«The use of nonhuman oocytes for SCNT is currently the only ethically justifiable option given the large numbers of eggs required to derive cloned human stem cell lines,» he said.

L: We use adult stem cells, and we use the human embryonic cell lines that the government has already approved.

The group urged the creation of two central databases: One on stem cell lines in use worldwide and one on intellectual property rights so scientists can readily access information.

Twenty - seven human embryonic stem cell (hESC) lines are ethically derived and should be approved for use in research funded by the US linkurl: National Institutes of Health; http://www.nih.gov/ (NIH), a committee advising the NIH director linkurl: recommended today (December 4).

His executive order allowed funding on embryonic stem - cell lines derived from embryos that had already been destroyed, but excluded funding of research using stem cells from embryos destroyed after August 9, 2001 (the date of his announced policy).

Only a few laboratories in the world are attempting this technique in human stem cell research and, thus far, no human stem cell lines have been derived using this method.

June 21, 2007: Bush vetoes another DeGette - sponsored bill that would allow research on all stem - cell lines using cells created for in - vitro fertilization and scheduled to be discarded.

What Collins does not say, however, is that the new NIH guidelines also allow for federal funds to be used in studying new human embryonic stem cell lines that are created (by private entities, of course) beyond the 700 currently in existence.

The new NIH guidelines do not permit the use of federal funds for creating new human embryonic stem cell lines.

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Using pre-implantation genetic diagnosis derived human embryonic stem cell lines (hES) or human induced pluripotent stem cells carrying the causal mutation for neuro - muscular diseases, our objective is double: identify new physiopathogical mechanisms and develop new therapeutic strategies.

Further phenotypic characterization revealed that LKB1 is required for the differentiation and maintenance of two NCC - derivatives, Schwann cells and the ENS. Using a model of neural crest stem cell line, we demonstrated that Lkb1 is key for neural crest - derived glial commitment.