Sentences with phrase «stem cell origin»
Unlike other fetal - derived stem cell origin, the amniotic fluid contains cells that arise from the developing fetus, at ratios and from origins that vary throughout pregnancy.
https://discovery.lifemapsc.com/ Not exact matches
In fact, the latest research in epigenetics, stem cells, and the developmental origins of health and disease is unlocking a whole new line of understanding of what breastmilk contains and its role in development.
The fourth theme addresses the ethical, legal, social, and policy issues related to the origins and use of stem cells.
«Genetic origins of myelodysplastic syndrome discovered using stem cells.»
Blood formation was the first process for which scientists formulated and proved the theory that stem cells are the common origin that gives rise to various types of mature cells.
Further dissecting the MDS stem cells at the molecular level could provide insights into the origins and development of MDS and other blood cancers.
Last May in Nature Neuroscience, his lab and a team at Columbia University reported that embryonic stem cells could be used to shed light on the origins of amyotrophic lateral sclerosis (ALS), the progressive neurodegenerative disease in which motor neurons in the brain die.
Because biologists like Daley are convinced that embryonic stem cells — the most generic, versatile type — may not only lead to dramatically different new treatments but can also uniquely illuminate the origins of disease in a way adult stem cells never will.
Conventional wisdom has long held that adult stem cells are only capable of forming their tissue of origin.
The MDS stem cells were rare, sat at the top of a hierarchy of MDS cells, could sustain themselves, replenish the other MDS cells, and were the origin of all stable DNA changes and mutations that drove the progression of the disease.
«New tools to study the origin of embryonic stem cells.»
The study had its origins in Anguera's postdoctoral research, which focused on X inactivation in pluripotent stem cells.
Recent studies highlighted significant differences between these two types of stem cells, although only a limited number of cell lines of different origins were analyzed.
Potential scientific questions from this research relate to the origin and function of stem cell clones and to whether they could be used to predict future outcomes.
Experiments conducted by lead author Fatima Syed - Picard, Ph.D., also of Pitt's Department of Ophthalmology, and the team showed that stem cells of the dental pulp, obtained from routine human third molar, or wisdom tooth, extractions performed at Pitt's School of Dental Medicine, could be turned into corneal stromal cells called keratocytes, which have the same embryonic origin.
Harvard Stem Cell Institute scientists at Brigham and Women's Hospital have found the cellular origin of the tissue scarring caused by organ damage associated with diabetes, lung disease, high blood pressure, kidney disease, and other conditions.
Derivation of pluripotent stem cells, either of embryonic origin or following genetic reprogramming, has opened the path for an alternative source for epidermal cell therapy as these cells are both immortal and pluripotent, theoretically capable of providing any requested number of cells of any desired phenotype.
We will have major players give state of the art talks in sessions including Avian Behavior, Avian Physiology, Avian Stem Cell & Transgenesis - related Techniques, Developmental Biology, Genetic / Genomic Analysis and the Origin and Evolution of Birds, etc..
Showing that stem cells or transient amplifying cells may exist in the periphery might explain the origin of HCECs and indicate a source for these cells in wound repair.
Researchers using ethically uncontroversial induced pluripotent stem cells (iPSCs) have achieved what appears to be a major breakthrough in understanding the origin and development of Down syndrome, according to a new study recently published in Nature Communications.
Matson JP, Dumitru R, Coryell P, et al., Rapid DNA replication origin licensing protects stem cell pluripotency.
Disease - specific human pluripotent stem cells, from embryonic origin or derived from reprogramming somatic cells, offer the unique opportunity to have access to a large spectrum of disease - specific cell models.
The actual cell of origin is different in each type of tumor, and does not have to be atumor stem cell.
Review of «Rapid DNA replication origin licensing protects stem cell pluripotency» from eLife by Stuart P. Atkinson
iPS cells are virtually identical to human embryonic stem cells (also called hESCs), which this column has discussed previously, except for their origins.
Unlike embryonic stem cells, which are developmental blank slates that can generate virtually all types of cells found in adult humans, adult stem cells are thought to possess limited potential to transform into cells found in their tissues of origin.
We developed and implemented such a nomenclature for the European human pluripotent stem cell registry (hPSCreg), which needs to: 1) unambiguously identify a registered cell line; 2) allow tracing of subclones of a particular line; and 3) enable the assignment of different lines to a specific donor origin.
Virtually identical to human embryonic stem cells (hESCs) except for their origin of isolation, the recently created induced pluripotent stem cells (iPSCs)(Yu et al., 2007; Takahashi et al., 2007) hold much potential for use in regenerative therapies.
The specific vocation of I - Stem is to explore all the therapeutic potential of human pluripotent stem cells for applications in patients affected by rare diseases of genetic oriStem is to explore all the therapeutic potential of human pluripotent stem cells for applications in patients affected by rare diseases of genetic oristem cells for applications in patients affected by rare diseases of genetic origin.
Applying these paradigms on various neural differentiation schemes of human pluripotent stem cells allows us to identify and isolate new types of neural stem and progenitor cells, to characterize their cellular properties and molecular foundations, to expose their progenitor origin and track their imminent potential, to reveal their in vivo counterparts and learn about their regenerative potential.
New research from the University of North Carolina establishes a link between rapid origin licensing and the maintenance of stem cell pluripotency
Dr. Péault, a professor in the Department of Pediatrics, Cell Biology and Physiology at the University of Pittsburgh School of Medicine, recognized the importance of determining the origin of these muscle - derived stem cells.
25) Barker N., Ridgway R.A., van Es J.H., van de Wetering M., Begthel H., van den Born M., Danenberg E., Clarke A.R., Sansom O.J., Clevers H. Crypt Stem Cells as the Cells - of - Origin of Intestinal Cancer Nature 457:608 - 611 (2009)
51) Drost, J., van Boxtel, R., Blokzijl, F., Mizutani, T., Sasaki, N., Sasselli, V., de Ligt, J., Behjati, S., Grolleman, J.E., van Wezel, T., Nik - Zainal, S., Kuiper, R.P., Cuppen, E., and Clevers, H. Use of CRISPR - modified human stem cell organoids to study the origin of mutational signatures in cancer.
Dr. Péault is internationally recognized principally for his work on the prospective identification and characterization of human hematopoietic (blood) stem cells, of which his laboratory has also deciphered the ultimate origin during embryonic life.
«Use of CRISPR - modified stem cell organoids to study the origin of mutational signatures in cancer»
Created in 2005 through a collaboration between Inserm — National Institute of Health and Medical Research — and AFM - Telethon — French Association against Myopathies — I - Stem is the largest French laboratory for research and development dedicated to human pluripotent stem cells, of embryonic origin or obtained by reprogramming gStem is the largest French laboratory for research and development dedicated to human pluripotent stem cells, of embryonic origin or obtained by reprogramming gstem cells, of embryonic origin or obtained by reprogramming gene.
This abnormality helps drive malignancy at the point of origin, and facilitates cancer stem cells to renew over the long term.
Hence, the FLI focuses on the origin of the aging - induced increases in molecular damage aiming to elucidate how it contributes to impairments in stem cell function and the evolution of organ dysfunction and diseases in aging.