Sentences with phrase «stem cell proliferation»

The findings demonstrate that gold nanoparticles that are modified in different ways have varying effects on stem cell proliferation and differentiation.

This new understanding now allows them to better predict the conditions that lead to normal stem cell proliferation.

They then used human stem cells derived from bone marrow that would normally become bone cells to test the effects of the nanoparticles on stem cell proliferation and differentiation.

Data analysis using Baysian self - learning algorithm to narrow target genes suspected to be involved in stem cell proliferation in the stem cell niche of the gonad arm.

Titled, «Aromatic - turmerone induces neural stem cell proliferation in vitro and in vivo,» German researchers evaluated the effects of this turmeric - derived compound on neural stem cells (NSCs)-- the subgroup of brain cells capable of continuous self - renewal required for brain repair.

In initial work with cell cultures in Petri dishes, the researchers methodically ruled out the possibility that HIV / gp120 would be inducing the death of stem cells and determined instead that HIV / gp120 was acting by inhibiting stem cell proliferation.

«We have only scratched the surface of the role of AIM2 in controlling stem cell proliferation and the maintenance of a healthy gut microbiota,» Kanneganti said.

«Ideally, we would change the chromatin state before we start overexpressing NEUROG1 and prevent unwanted stem cell proliferation,» he said.

Numb therefore stabilizes p53 and allows this tumor suppressor protein to limit stem cell proliferation.

«Scientists describe a function for autophagy in germline stem cell proliferation.»

Scientists from the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden recently discovered a new mechanism governing brain stem cell proliferation.

The nanoparticles with the negative biomolecules on their surface promoted stem cell proliferation but suppressed «matrix mineralization»: the process that leads to the deposition of minerals into the bone's scaffolding, which makes bones strong.

Under experimental conditions, they were able to neutralize the p38 MAPK pathway and restore stem cell proliferation.

Lipton and colleagues now report that the p38 MAPK pathway is also the mechanism underlying decreased stem cell proliferation in the brain associated with HIV / AIDS.

The new knowledge and target candidate genes resulted from such unbiased study are ultimately important for researchers to understand the fundamental nature of stem cell proliferation and differentiation.»

Conversely, malfunction of AIM2 unleashes abnormal stem cell proliferation.

Notch signaling is essential for radial glia stem cell proliferation and a determinant of neuronal number in the mammalian cortex.

We want to understand how neural stem cell proliferation is tightly controlled, both spatially and temporally, to allow for the efficient formation of the highly organized neocortex.

The positively charged and neutral nanoparticles mildly inhibited stem cell proliferation but had no effect on their differentiation into bone cells.

Scientists study the germline of the roundworm Caenorhabditis elegans to identify the mechanisms that control stem cell proliferation and homeostasis, as well as to advance our molecular understanding of homologous signaling pathways humans.

Changes in chromatin may help reduce unwanted stem cell proliferation and can be achieved by adding drugs to experimental cultures in Petri dishes, Kwan said.

As an example, he cited his previous research on baked purple potatoes that have compounds that help suppress chronic intestinal inflammation elevated from a high - calorie diet and stem cell proliferation, which are linked to both colitis and colon cancer.

«We're looking at the genes and gene networks involved in stem cell proliferation, meristem development and flowering and branching,» said Van Eck, «with the end goal being that maybe genes that we identify in tomato, which is strictly being used as a model, might help us understand what can be done to increase yield in other crops.»

Drs. Stuart Lipton, Marcus Kaul, Shu - ichi Okamoto and their colleagues uncovered a novel molecular mechanism that inhibits stem cell proliferation and that could possibly be triggered in other neurodegenerative diseases as well.

The vasculature can influence neural stem cell proliferation and differentiation by providing a local source of signaling molecules secreted from endothelial cells (1) as well as by delivering systemic regulatory factors (2).

This effect was also observed in a live animal model, showing that rats injected with ar - tumerone into their brains experienced increases in neural stem cell proliferation and the creation of newly formed healthy brain cells.